The Gordon Research Seminar on Phagocytes is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.
This meeting will cover a broad range of aspects of phagocytes functions, especially how phagocytic cells such as monocytes, macrophages, and neutrophils play essential roles during host defense, inflammation, infection, and homeostasis. Learning more about host interaction with invasive pathogens will provide insight into their regulation at the cell and molecular level.
|1:00 pm - 5:00 pm||Arrival and Check-in|
|3:30 pm - 3:45 pm||Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair|
|3:45 pm - 4:30 pm||Chemotaxis of Inflammatory Cells|
|Discussion Leader: Marco A.O. Magalhaes (Albert Einstein College of Medicine, NY, USA)|
|3:45 pm - 4:00 pm||Athanassios Dovas (Albert Einstein College of Medicine, NY, USA)|
"Phospho-dependent interaction between WASp and Intersectin-2L regulates macrophage chemotaxis"
|4:00 pm - 4:05 pm||Discussion|
|4:05 pm - 4:20 pm||Robert Pick (Ludwig-Maximilians-Universitat München, Germany)|
"Adhesion strengthening, spreading and crawling of neutrophils critically depend on coronin 1A"
|4:20 pm - 4:25 pm||Discussion|
|4:25 pm - 4:30 pm||General Discussion|
|4:30 pm - 6:00 pm||Poster Session I|
|7:30 pm - 9:30 pm||Host-Pathogen Interactions|
|Discussion Leader: Michelle Lennartz (Albany Medical College, NY, USA) and Amber T. Kaplan (Cedars-Sinai Medical Center, CA, USA)|
|7:30 pm - 7:50 pm||Kan Chen (Brigham and Women's Hospital, MA, USA)|
"A role for FcgammaRIIIB in neutrophil recruitment and clearance of intravascular immune complexes: Implications for autoimmune disease"
|7:50 pm - 8:00 pm||Discussion|
|8:00 pm - 8:20 pm||Michael J. Davis (University of Michigan, MI, USA)|
"Inducible lysosome renitence inhibits Listeria infection in macrophages"
|8:20 pm - 8:30 pm||Discussion|
|8:30 pm - 8:50 pm||Matthew Long (University of Iowa, IA, USA)|
"Francisella tularensis mutants with defects in LPS O-antigen and capsule biosynthesis exhibit pleiotropic virulence defects and induce rapid macrophage death"
|8:50 pm - 9:00 pm||Discussion|
|9:00 pm - 9:20 pm||Fabio Munari (Venetian Institute of Molecular Medicine, Italy)|
"Macrophages and neutrophils as major source of APRIL and BLyS in Helicobacter pylori sustained pathologies."
|9:20 pm - 9:30 pm||Discussion|
|7:30 am - 8:30 am||Breakfast|
|9:00 am - 11:00 am||Phagosome Maturation|
|Discussion Leader: Becky A. Diebold (Emory University, GA, USA) and Shashank Shekhar (University of Twente, Netherlands)|
|9:00 am - 9:20 am||Paula Nunes (University of Geneva, Switzerland)|
"STIM1-mediated recruitment of ER membranes to nascent phagosomes."
|9:20 am - 9:30 am||Discussion|
|9:30 am - 9:50 am||Helen Sarantis (Hospital for Sick Children, Canada)|
"A role for Rab5 in bacterial entry into host cells"
|9:50 am - 10:00 am||Discussion|
|10:00 am - 10:20 am||Christine Becker (Massachusetts General Hospital, MA, USA)|
"A lysosomal resident GTPase that interacts with caspase-1 and is important for regulating trafficking in the innate immune system"
|10:20 am - 10:30 am||Discussion|
|10:30 am - 10:50 am||Michal Bohdanowicz (Hospital for Sick Children, Canada)|
"APPL1 recruits two phosphoinositide 5-phosphatases that reduce Akt activation during phagocytosis."
|10:50 am - 11:00 am||Discussion|
|11:00 am - 12:30 pm||Poster Session II|
|Coffee will be served in the poster area from 11:00 am - 11:30 am|
|1:30 pm - 2:30 pm||Mentorship Session|
|Discussion Leader: Lee-Ann Allen (University of Iowa, IA, USA)|
|1:30 pm - 2:30 pm||Sergio Grinstein (Hospital for Sick Children, Canada)|
"The Big Transition: From Ph.D. to Career"
|2:30 pm - 3:00 pm||Evaluation Period|
|Fill out GRS Evaluation Forms|
|3:00 pm||Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm.|