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Conference Program
 
Mycotoxins & Phycotoxins
June 12-17, 2011
Colby College
Waterville, ME

Related Meeting Information
The Mycotoxins & Phycotoxins Gordon Research Conference was held in conjunction with the Mycotoxins & Phycotoxins Gordon-Merck Research Seminar. Please refer to the Mycotoxins & Phycotoxins GMRS web page for more information.

Fungi, algae and cyanobacteria are capable of producing an expansive array of toxic secondary metabolites that adversely affect the health of humans and animals. Mycotoxins and phycotoxins are found in food, water and air. The frequency and intensity of their occurrence is often impacted by environmental change and human activity. Given the ecological and societal importance of this field, numerous disciplines (e.g., analytical chemistry, toxicology, ecology, plant pathology, epidemiology, genomics/proteomics, meteorology, economics and risk assessment/hazard management) within the public and private sectors have been involved in addressing the myriad problems associated with the occurrence of these natural toxins.

The 15th Gordon Research Conference on Mycotoxins and Phycotoxins offers a unique international forum for academic, governmental and industrial scientists to exchange ideas, identify new research opportunities and initiate cross-disciplinary collaborations. Contemporary themes will be explored to facilitate the discussion of the “what, how, who, when, and why” of natural toxin events. Themes will include: 1) novel toxins and toxicities, 2) molecular mechanisms of toxicity and detoxification, 3) public health effects/disease epidemiology, 4) societal and economic impacts, 5) genetic and environmental control of toxigenesis, 6) physiological and ecological roles of toxins, 7) detection and predictive modeling and 8) risk assessment and abatement.

A primary goal of this unique gathering is to create a critical mass and atmosphere for creative thinking necessary to advance knowledge of the complex environmental and societal problems presented by naturally occurring toxigenic microbes and their toxins. Special consideration will be given to strategies to improve interactions of junior and senior scientists during the conference. In keeping with the ethos of Gordon Research Conferences, while information will be disseminated by speaker presentations, vigorous discussion will be the key focus. Designated discussion leaders, recognized for their skills in each particular area, will guide the audience-based discussions. Poster sessions will provide an opportunity for lively and informal discussion, in counterpoint to the more formal oral sessions.

In addition, the Gordon Research Seminar (GRS) will convene immediately preceding the GRC (11-12 June 2011). Organized and conducted by graduate students and postdocs, the GRS will provide an opportunity for junior scientists to present their work in a formal, oral format, in front of their peers. These students will participate in the subsequent Mycotoxins and Phycotoxins GRC providing an unmatched opportunity to promote interactions between future researchers and established ones.


Contributors

SUNDAY
2:00 pm - 9:00 pmArrival and Check-in (Office Closed 6:00 pm - 7:00 pm)
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmA Common Roadmap for Biotoxin Research
Discussion Leaders: Vera Trainer (NOAA Seattle) and Jim Pestka (Michigan State)
7:40 pm - 8:20 pmGary Payne (North Carolina State University)
"Genetic processes regulating secondary metabolite biosynthesis"
8:20 pm - 8:35 pmDiscussion
8:35 pm - 9:15 pmCharles Trick (University of Western Ontario, Canada)
"But they said it was a toxin!"
9:15 pm - 9:30 pmDiscussion
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmExposure Assessment
Discussion Leaders: Lora Fleming (European Centre for Environment and Human Health, UK) and Sara Henry (USFDA-CFSAN, U.S.)
9:00 am - 9:30 amIan Stewart (Queensland Health Forensic and Scientific Services, Brisbane, Australia)
"Overview of the cyanotoxins from the human health/exposure perspective"
9:30 am - 9:45 amDiscussion
9:45 am - 10:15 amPaul Turner (School of Public Health, University of Maryland, College Park)
"Development, validation and effects of dietary intervention on a deoxynivalenol exposure biomarker"
10:15 am - 10:30 amDiscussion
10:30 am - 11:00 amGroup Photo / Coffee Break
11:00 am - 11:30 amKate Sullivan (University of Alaska Southeast, Ketchikan)
"Epidemiology of paralytic shellfish poisoning in Alaska"
11:30 am - 11:45 amDiscussion
11:45 am - 12:15 pmLiana van der Westhuizen (PROMEC-MRC, South Africa)
"Biomarkers of fumonisin exposure and the impact of intervention among South African subsistence farmers"
12:15 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmNew Insights from Taxonomic and Ecological Studies
Discussion Leaders: Mark Wells (University of Maine) and Donald Wicklow (USDA-ARS, Peoria)
7:30 pm - 7:50 pmJohn Pitt (CSIRO, Australia)
"Good mycotoxicology requires good taxonomy: recent taxonomic developments and some consequences"
7:50 pm - 8:00 pmDiscussion
8:00 pm - 8:20 pmGustaaf Hallegraeff (University of Tasmania, Australia)
"Harmful algal blooms: ship ballast water translocations and climate driven range extensions"
8:20 pm - 8:30 pmDiscussion
8:30 pm - 8:50 pmIgnazio Carbone (North Carolina State U.)
"Toxigenesis in the aspergilli"
8:50 pm - 9:00 pmDiscussion
9:00 pm - 9:20 pmRobert Bidigare (University of Hawaii)
"Ciguatoxin and BMAA bioaccumulation in marine food webs"
9:20 pm - 9:30 pmDiscussion
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmMechanisms of Action
Discussion Leaders: Kathleen Rein (Florida International University) and Isabelle Oswald (INRA, France)
9:00 am - 9:30 amCathy Walsh (Mote Marine Lab)
"Effects of brevetoxins on cellular pathways in immune cells"
9:30 am - 9:45 amDiscussion
9:45 am - 10:15 amBrenna Flannery (Michigan State University)
"Mechanism(s) of trichothecene-induced anorexia and growth suppression"
10:15 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:30 amJames Ryan (NOAA Charleston)
"Transcriptional profiling of mammalian model organisms upon exposure to marine toxins"
11:30 am - 11:45 amDiscussion
11:45 am - 12:15 pmGenevieve Bondy (Health Canada)
"Effects of chronic dietary mycotoxin exposure on the p53+/- mouse"
12:15 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmAnalytical Advances
Discussion Leaders: Chris Elliott (Queen's University Belfast) and Rudi Krska (BOKU, Austria)
7:30 pm - 7:55 pmCraig Woolsey (Virginia Tech)
"Environmental sampling with autonomous UAVs and underwater gliders"
7:55 pm - 8:10 pmDiscussion
8:10 pm - 8:35 pmChristopher O. Miles (Norwegian Veterinary Institute)
"Novel techniques to the discovery, structural identification, and detection of biotoxins"
8:35 pm - 8:50 pmDiscussion
8:50 pm - 9:15 pmKatrina Campbell (Queen's University)
"Evolving to the optoelectronic mouse for multi-toxin analysis"
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmNovel Bioactivities, Functional Genomics, and Pathologies
Discussion Leaders: Micaela Parker (University of Washington) and Roger Coulumbe (Utah State U.)
9:00 am - 9:30 amWilliam Gerwick (Scripps)
"Novel toxins and therapeutic leads from the natural products of marine cyanobacteria"
9:30 am - 9:45 amDiscussion
9:45 am - 10:15 amHans-Ulrich Humpf (Universitaet Muenster)
"New fumonisin metabolites: The in-vivo formation of N-acyl-fumonisin B1 by the ceramide synthase and influence on the sphingolipid metabolism"
10:15 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:30 amDebashish Bhattacharya (Rutgers University)
"Genomics of red-tide causing dinoflagellates"
11:30 am - 11:45 amDiscussion
11:45 am - 12:15 pmJ. David Miller (Carleton U)
"Low molecular weight fungal metabolites and non-atopic asthma"
12:15 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair
7:30 pm - 9:30 pmThe Changing World: Outstanding GRS Presenters / Impacts of Climate Change
Discussion Leaders: Kevin Sellner (Chesapeake Research Consortium) and Wayne Bryden (U. Queensland, Australia)
7:30 pm - 7:40 pmShort Talk: Best junior scientist GRS speaker - Mycotoxins - TBA
7:40 pm - 7:50 pmDiscussion
7:50 pm - 8:00 pmShort talk: Best junior scientist GRS speaker - Phycotoxins - TBA
8:00 pm - 8:10 pmDiscussion
8:10 pm - 8:35 pmStephanie Moore (NOAA Seattle)
"Impact of climate on harmful algal blooms and prediction of toxic marine events"
8:35 pm - 8:50 pmDiscussion
8:50 pm - 9:15 pmNaresh Magan (Cranfield University)
"Impact of climate change on mycotoxin incidence"
9:15 pm - 9:30 pmDiscussion
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmStrategies for Prevention and Control
Discussion Leaders: Allen Place (University of Maryland) and Barbara Blackwell (Agriculture Canada)
9:00 am - 9:30 amJulia Kubanek (Georgia Institute of Technology School of Biology)
"Mitigation of red tide brevetoxins by competing phytoplankton"
9:30 am - 9:45 amDiscussion
9:45 am - 10:15 amChristina Cowger (USDA/North Carolina State)
"Integrated approach of USDA Wheat & Barley Scab Initiative for managing Fusarium vomitoxin"
10:15 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:30 amIchiro Imai (Hokkaido University)
"Biocontrol of harmful algae using competitors and killers"
11:30 am - 11:45 amDiscussion
11:45 am - 12:15 pmPeter Cotty (USDA/U. Arizona)
"Control of aflatoxin biosynthesis in the field using competing strains of non-toxigenic Aspergillus species"
12:15 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmBiotoxin Research - The Future
Discussion Leaders: Julie Dyble-Bressie (NOAA Great Lakes Lab) and Kenneth Voss (USDA-Athens)
7:30 pm - 8:10 pmKeynote Address: Daniel Baden (Director of the Center for Marine Science) and William R. Kenan Jr. (Distinguished Professor of Marine Sciences at University of North Carolina at Wilmington)
"The Future of Biotoxin Research: Vision or Hallucination."
8:10 pm - 8:30 pmDiscussion
8:30 pm - 8:40 pmSpeaker 1 Hot Topic
8:45 pm - 8:50 pmDiscussion
8:55 pm - 9:05 pmSpeaker 2 Hot Topic
9:05 pm - 9:10 pmDiscussion
9:10 pm - 9:20 pmSpeaker 3 Hot Topic
9:20 pm - 9:25 pmDiscussion
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDeparture

 
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