Gordon Research Conferences
PI_Conferences PI_Conferences_Past
Conference Program
 
Biology of Acute Respiratory Infection
Host-Pathogen Interactions in the Lung
March 11-16, 2012
Ventura Beach Marriott
Ventura, CA

Acute respiratory infections such as pneumonia and influenza are an enormous public health problem, and trends suggest that the burden of disease due to viral, bacterial and fungal respiratory infection is likely to get worse rather than better in the coming years. The 2012 Gordon Research Conference (GRC) on Biology of Acute Respiratory Infections will focus attention on host-pathogen interactions including innate immunity, pathophysiology of disease, pathogenesis & virulence of the organisms and clinical disease & interventions. Perspectives to be considered include microbiology, immunology and physiology. Speakers have been chosen to give a broad, up-to -date overview of this rapidly evolving and multi-disciplinary field. The consistent aim of the GRC on Biology of Acute Respiratory Infections has been to bring together an outstanding and diverse group of experts from basic and applied science and clinical research from across the globe to foster communication among individuals and groups studying this common and important problem from distinct vantage points, to develop and encourage creative and multidisciplinary approaches to discovery. Elucidating the biology of respiratory infections will facilitate the development of innovative, effective prevention and treatment strategies for acute respiratory infections.

The chairs have set up a blog to provide information about the speakers scheduled for the 2012 Biology of Acute Respiratory Infection GRC. Click here for details.


Contributors

SUNDAY
4:00 pm - 8:00 pmArrival and Check-in (Office Closed 6:00 pm - 7:45 pm)
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmOverview: Host-Pathogen interactions in the lung
Discussion Leader: Joseph Mizgerd (Boston University School of Medicine)
7:40 pm - 8:25 pmBali Pulendran (Emory Vaccine Center)
"Dendritic Cell biology in the host response to pneumonia"
8:25 pm - 8:35 pm Discussion
8:35 pm - 9:20 pmSteven Holland (NIAID)
"Defects in innate immunity and pneumonia"
9:20 pm - 9:30 pm Discussion
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmEpithelial cell signaling and immunity in lung infection
Discussion Leader: Theodore Standiford (University of Michigan)
9:00 am - 9:45 amPeter Openshaw (Imperial College London)
"How RSV causes disease"
9:45 am - 10:00 amDiscussion
10:00 am - 10:30 amGroup Photo / Coffee Break
10:30 am - 11:00 amNicholas Lukacs (University of Michigan)
"Respiratory syncytial virus-induced pathogenesis and regulation of pulmonary immune responses"
11:00 am - 11:10 amDiscussion
11:10 am - 11:40 amSteven Varga (University of Iowa)
"Regulation of the RSV-specific CD8 T cell response"
11:40 am - 11:50 amDiscussion
11:50 am - 12:20 pmJeffrey Whitsett (Cincinnati Children's Hospital)
"Regulation of innate immunity by the respiratory epithelium"
12:20 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session I (last names A-K)
6:00 pmDinner
7:30 pm - 9:30 pmBacterial infections: genomics/pathogenesis/epidemiology
Discussion Leader: Juliane Bubeck-Wardenburg (University of Chicago)
7:30 pm - 8:15 pmJuliane Bubeck-Wardenburg (University of Chicago)
"The contribution of alpha-hemolysin to S. aureus pathogenesis"
8:15 pm - 8:25 pmDiscussion
8:25 pm - 8:55 pmBinh An Diep (UCSF)
"Pathogenesis of S. aureus necrotizing pneumonia"
8:55 pm - 9:00 pmDiscussion
9:00 pm - 9:25 pmMin Li (Fudan University)
"The molecular basis of an MRSA epidemic wave in China"
9:25 pm - 9:30 pmDiscussion
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmInnate Immunity / Bacterial infection
Discussion Leader: Jane Deng (UCLA Medical Center)
9:00 am - 9:30 amAugustine Choi (Harvard Medical School)
"Crosstalk between autophagy and inflammasomes in innate immunity"
9:30 am - 9:40 amDiscussion
9:40 am - 10:10 amJerry Simecka (UNT Health Science Center)
"Immunopathology of Mycoplasma Pneumonia"
10:10 am - 10:20 amDiscussion
10:20 am - 10:40 amCoffee Break
10:40 am - 11:10 amEric Harvill (Penn State University)
"Immunopathogenesis of pertussis"
11:10 am - 11:15 amDiscussion
11:15 am - 11:45 amThomas Clark (CDC)
"Pertussis: Current Epidemiology and Implications for Vaccination Programs"
11:45 am - 11:50 amDiscussion
11:50 am - 12:05 pmShort Talk: Kenichi Shimada (Cedars-Sinai Medical Center)
"Activation of the NLRP3 Inflammasome by Oxidized Mitochondrial DNA during Apoptosis"
12:05 pm - 12:10 pmDiscussion
12:10 pm - 12:25 pmShort Talk: Vijay Sivaraman (University Of North Carolina)
"Characterization of Early Immune Responses During Primary Pneumonic Plague"
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session I (last names A-K)
6:00 pmDinner
7:30 pm - 9:30 pmImmunopathogenesis of fungal infection
Discussion Leader: Chad Steele (University of Alabama at Birmingham)
7:30 pm - 7:55 pmGeorge Deepe (University of Cincinnati College of Medicine)
"Chemokine-Cytokine Nexus and Fungal Immunity in the Lung"
7:55 pm - 8:00 pmDiscussion
8:00 pm - 8:25 pmStuart Levitz (University of Massachusetts Medical School)
"Plasmacytoid dendritic cells in fungal host defenses"
8:25 pm - 8:30 pmDiscussion
8:30 pm - 8:55 pmTobias Hohl (Fred Hutchinson Cancer Research Center)
"Host defense against respiratory fungal infection"
8:55 pm - 9:00 pmDiscussion
9:00 pm - 9:25 pmMarcel Wuethrich (University of Wisconsin)
"The induction of vaccine-induced anti-fungal T17 cells"
9:25 pm - 9:30 pmDiscussion
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmInflammasome/Autophagy/Influenza
Discussion Leader: Jim Crowe (Vanderbilt University Medical Center)
9:00 am - 9:30 amAlan Hauser (Northwestern University)
"An rhs gene of Pseudomonas aeruginosa enhances virulence and activates the inflammasome"
9:30 am - 9:35 amDiscussion
9:35 am - 10:05 amIrving Coy Allen (University of North Carolina at Chapel Hill)
"The role of NLRs during acute respiratory infection"
10:05 am - 10:15 amDiscussion
10:15 am - 10:30 amCoffee Break
10:30 am - 11:00 amAdolfo Garcia-Sastre (Mount Sinai School of Medicine)
"Induction and evasion of interferon responses by influenza viruses"
11:00 am - 11:05 amDiscussion
11:05 am - 11:35 amDaniel Perez (University of Maryland)
"Is there room for the influenza 'transmisome'?"
11:35 am - 11:40 amDiscussion
11:40 am - 12:10 pmJasmine Perez (Mount Sinai School of Medicine)
"The biology of Influenza A Virus-Generated Small RNAs"
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:25 pmShort Talk: Sarah Vaughan (Lovelace Respiratory Research Institute)
"Attenuated Dendritic Cell Function and Lack of Protection in BALB/c Mice Following HPAI Vaccination"
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session II (last names L-Z)
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair
7:30 pm - 9:30 pmImmune cell recruitment and signaling in bacterial infection
Discussion Leader: Anuradha Ray (University of Pittsburgh)
7:30 pm - 8:00 pmJay Kolls (LSU)
"Mucosal Immune requirements for prevention of infection with multi-drug resistant Klebsiella pneumoniae"
8:00 pm - 8:10 pmDiscussion
8:10 pm - 8:40 pmPaul Kubes (University of Calgary)
"Mechanisms of PMN recruitment"
8:40 pm - 8:50 pmDiscussion
8:50 pm - 9:20 pmTheodore Standiford (University of Michigan)
"Response of the lung to sepsis"
9:20 pm - 9:30 pmDiscussion
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmVaccines and Respiratory Viruses
Discussion Leader: Joan Durbin (NYU Langone Medical Center)
9:00 am - 9:30 amHana Golding (FDA)
"Expansion of antibody repertoires and affinity maturation following infection or vaccination with influenza viruses"
9:30 am - 9:40 amDiscussion
9:40 am - 10:10 amUrsula Buchholz (NIAID)
"Host response to pneumovirus infection"
10:10 am - 10:20 amDiscussion
10:20 am - 10:40 amCoffee Break
10:40 am - 11:10 amStephania Cormier (Louisiana State University Health Sciences Center)
"Why Timing of Initial RSV Infection is Important"
11:10 am - 11:15 amDiscussion
11:15 am - 11:45 amJames Crowe (Vanderbilt University Medical Center)
"Respiratory virus infection of polarized epithelial cells"
11:45 am - 11:55 amDiscussion
11:55 am - 12:25 pmPaul Planet (Columbia University)
"Evolution of the USA300 genome"
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session II (last names L-Z)
6:00 pmDinner
7:30 pm - 9:30 pmBacterial/Viral co-infection and the resolution of pneumonia
Discussion Leader: Ursula Buchholz (NIAID)
7:30 pm - 7:40 pmThomas Kuri (Karolinska Institute, MTC)
"Influenza virus selectively enhances IL-12p70 secretion by human dendritic cells infected with Streptococcus pneumonia"
7:40 pm - 7:45 pmDiscussion
7:45 pm - 8:15 pmSuzanne Dawid (University of Michigan)
"The role of bacterial competition in respiratory tract colonization by Streptococcus pneumoniae"
8:15 pm - 8:25 pmDiscussion
8:25 pm - 8:35 pmPrabir Ray (University Of Pittsburgh)
"Lung Interstitial MDSC-like Cells In Resolution of Tissue Inflammation After Bacterial Pneumonia"
8:35 pm - 8:40 pmDiscussion
8:45 pm - 9:15 pmBruce Levy (Harvard Medical School)
"Lipoxins and resolvins promote the resolution of bacterial pneumonia and ALI"
9:15 pm - 9:25 pmDiscussion
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDeparture

Funding for this conference was made possible [in part] by 1R13AI098123-01 from the National Institute of Allergy and Infectious Diseases. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

 
© 2013 Gordon Research Conferences. All Rights Reserved. Search | Contact | Terms of Use | Privacy Policy | Follow us: Facebook Twitter