Gordon Research Conferences
PI_Conferences PI_Conferences_Past
Conference Program
 
 
 
QUICK SEARCH
GO
[ advanced search ]
 
 
 
Biocatalysis
July 8-13, 2012
Bryant University
Smithfield, RI
Chairs:
Stefan Lutz & Hans-Peter Meyer

Vice Chairs:
Joelle N. Pelletier & Oliver May
Related Meeting Information
The Biocatalysis Gordon Research Conference was held in conjunction with the Biocatalysis Gordon Research Seminar. Please refer to the Biocatalysis GRS web page for more information.

Biocatalysis encompasses the use of enzymes or whole cell systems for effecting the conversion of readily available, inexpensive starting materials to high value products. Enzymes are fully recyclable catalytic proteins that frequently display exquisite chemo-, enantio- and regioselectivity and operate under mild conditions of pH and temperature. These characteristics make them cost effective and sustainable catalysts for a wide range of chemical transformations. Modern tools of protein discovery, design and engineering aid the development of novel biocatalysts and their tailor-designed integration into industrial processes. Consequently, they find wide application in the production of pharmaceutical intermediates, novel materials and diagnostics,as well as fine, performance and agrochemicals. The Biocatalysis Gordon Conference highlights the best science, technologies and case studies responsible for the understanding, development and practical use of biocatalysts around the world.

Contributors
SUNDAY
2:00 pm - 9:00 pmArrival and Check-in (Office Closed 6:00 pm - 7:00 pm)
6:00 pmDinner
7:30 pm - 7:45 pmWelcome / Introductory Comments by GRC Site Staff and Chair's Welcome - Stefan Lutz (Emory, USA)
7:45 pm - 9:00 pmPAST, PRESENT AND FUTURE OF BIOCATALYSIS
Discussion Leader: Stefan Lutz (Emory, USA)
7:45 pm - 8:45 pmKeynote Address: Jay Keasling (UC Berkeley, USA)
"Opportunities and challenges for synthetic biology in biocatalysis"
8:45 pm - 9:00 pmDiscussion
MONDAY
7:30 am - 8:30 amBreakfast
8:30 amGroup Photo
9:00 am - 12:30 pmDESIGN AND ENGINEERING OF BIOCATALYSIS
Discussion Leader: Yashuhisa Asano (Toyama Pref. Univ., Japan)
9:00 am - 9:30 amUwe Bornscheuer (Univ. Greifswald, Germany)
"Protein engineering on the move: from directed evolution to in silico approaches"
9:30 am - 9:45 amDiscussion
9:45 am - 10:30 amPimchai Chaiyen (Mahidol University, Thailand)
"Biocatalysis by flavin-dependent enzymes"
10:30 am - 10:45 amDiscussion
10:45 am - 11:00 amCoffee Break
11:00 am - 11:30 amRomas Kazlauskas (Univ. Minnesota, USA)
"New catalytic activities in ancestral, stem-cell-like, enzymes"
11:30 am - 11:45 amDiscussion
11:45 am - 12:15 pmClarissa Czekster (Albert Einstein College of Med., USA)
"Dihydroneopterin aldolase from Mycobacterium tuberculosis catalyzes three distinct reactions"
12:15 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session I
6:00 pmDinner
7:30 pm - 9:30 pmDESIGN AND ENGINEERING OF PROCESSES
Discussion Leader: Oliver May (DSM, Germany)
7:30 pm - 8:00 pmJohn Woodley (Technical University of Denmark, Denmark)
"Process engineering for transaminase-catalyzed reactions"
8:00 pm - 8:15 pmDiscussion
8:15 pm - 8:45 pmToni Glieder (Austrian Centre of Industrial Biotechnol., Austria)
"New tools and concepts for human drug metabolite synthesis"
8:45 pm - 9:00 pmDiscussion
9:00 pm - 9:20 pmGjalt Huisman (Codexis Inc., USA)
"Multi-enzyme reactions for large scale oxidations"
9:20 pm - 9:30 pmDiscussion
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmCASCADE REACTIONS AND SYNTHETIC BIOLOGY
Discussion Leader: Joelle Pelletier (Univ. Montreal, Canada)
9:00 am - 9:30 amKristala Jones Prather (MIT, USA)
"Modularization of pathways to facilitate whole cell biocatalysis"
9:30 am - 9:45 amDiscussion
9:45 am - 10:30 amSven Panke (ETH Zurich, Switzerland)
"Optimizing in vitro multi-step pathways"
10:30 am - 10:45 amDiscussion
10:45 am - 11:00 amCoffee Break
11:00 am - 11:30 amClaudia Schmidt-Dannert (Univ. Minnesota, USA)
"Biosynthesis and designer microbes"
11:30 am - 11:45 amDiscussion
11:45 am - 12:15 pmSeung-Goo Lee (KRIBB, Rep. Korea)
"Development of genetic circuits for rapid and sensitive screening of various enzyme activities from metagenomic libraries"
12:15 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session II
6:00 pmDinner
7:30 pm - 9:30 pmROUND-TABLE: TRENDS IN APPLIED BIOCATALYSIS
Discussion Leader: Hans-Peter Meyer (Lonza)
7:30 pm - 7:45 pmIntroduction: Hans-Peter Meyer (Lonza, Switzerland)
7:45 pm - 9:15 pmRound Table: Jeffrey Moore (Merck, USA), Kai Baldenius (BASF, Germany), and Yoshihiko Hirose (Amano Enzyme, Japan)
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmBIOCATALYSTS IN SYNTHESIS
Discussion Leader: John Woodley (Technical Univ. of Denmark)
9:00 am - 9:30 amYashuhisa Asano (Toyama Prefectural Univ., Japan)
"Use of enzymes from microbial and plant 'Aldoxime-Nitrile Pathway' for organic synthesis"
9:30 am - 9:45 amDiscussion
9:45 am - 10:30 amDavid Berkowitz (Univ. Nebraska, USA)
"Leveraging New Chemistry-Enlisting Enzymes as Both Catalytic Agents & Reporters"
10:30 am - 10:45 amDiscussion
10:45 am - 11:00 amCoffee Break
11:00 am - 11:30 amSarah O'Connor (The John Innes Centre, UK)
"Elucidating monoterpene indole alkaloid biosynthesis"
11:30 am - 11:45 amDiscussion
11:45 am - 12:15 pmNick Turner (Univ. Manchester, UK)
"Design and Evolution of New Biocatalysts for Organic Synthesis"
12:15 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session I
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair
7:30 pm - 9:30 pmFUTURE CHALLENGES AND OPPORTUNITIES FOR BIOCATALYSIS
Discussion Leader: Uwe Bornscheuer (Univ. Greifswald,Germany)
7:30 pm - 8:00 pmVincent Rotello (Univ. Mass. Amherst, USA)
"Engineering the nanoparticle-protein interface"
8:00 pm - 8:15 pmDiscussion
8:15 pm - 8:45 pmEmily Balskus (Harvard Univ., USA)
"Development of microbially-generated reagents: transition metal catalysis in the presence of hydrogen producing bacteria"
8:45 pm - 9:00 pmDiscussion
9:00 pm - 9:20 pmJon Dordick (RPI, USA)
"Biocatalytic Nanocomposites: Painting a Bright Future"
9:20 pm - 9:30 pmDiscussion
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmINDUSTRIAL BIOCATALYSIS
Discussion Leader: Gjalt Huisman (Codexis, USA)
9:00 am - 9:30 amJeffrey Moore (Merck, USA)
"Biocatalysis at Merck - lessons from Sitagliptin and beyond"
9:30 am - 9:45 amDiscussion
9:45 am - 10:30 amYan Feng (Shanghai Jiao Tong University, China)
"The design of hyperthermophilic lipase chimeras by key motif-directed recombination"
10:30 am - 10:45 amDiscussion
10:45 am - 11:00 amCoffee Break
11:00 am - 11:30 amKai Baldenius (BASF, Germany)
"Moving biocatalysis research out of the chiral niche"
11:30 am - 11:45 amDiscussion
11:45 am - 12:15 pmLinda Thöny-Meyer (EMPA, Switzerland)
"Structural insights from random mutagenesis of Campylobacter jejuni oligosacchayl transferase PglB"
12:15 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session II
6:00 pmDinner
7:30 pm - 9:30 pmFUTURE CHALLENGES IN GREEN CHEMISTRY
Discussion Leader: Hans-Peter Meyer (Lonza, Switzerland)
7:45 pm - 8:30 pmJohn Warner (Founder/CTO Warner Babcock Institute Green Chem, USA)
"Biocatalysis and materials sciences: examples of green chemistry"
8:30 pm - 8:45 pmDiscussion
8:45 pm - 9:20 pmMichael Gonzales (Office of R&D, EPA, USA)
"The application and role of green chemistry in biocatalysis"
9:20 pm - 9:30 pmDiscussion
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDeparture
 
© 2013 Gordon Research Conferences. All Rights Reserved. Search | Contact | Terms of Use | Privacy Policy | Follow us: Facebook Twitter