| SATURDAY |
| 2:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Keynote Lecture |
| 3:45 pm - 4:15 pm | Steve Crowley (Duke University, Durham)
"The role of the renin angiotensin system on inflammation and immune response: the bad family with some good relatives" |
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Angiotensin in development, immunity and inflammation |
| Discussion Leaders: Robert Regenhardt (University of Florida, Gainesville) and David Harrison (University of Vanderbilt, Nashville) |
| 7:30 pm - 7:50 pm | Arndt Manzel (Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany)
"Role of the RAS in autoimmune inflammation of the CNS" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Jose Gomez (Duke University, Durham)
"Contribution of kidney mesenchymal stem cells to renin producing cells" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Gregory Shen (Cedar-Sinai Medical Center, Los Angeles)
"Angiotensin converting enzyme shapes the MHC class I peptide repertoire" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:10 pm | Ulrike Maschke (Max Delbrück Center, Berlin, Germany)
"Deletion of (Pro)renin receptor impairs T cell development" |
| 9:10 pm - 9:15 pm | Discussion |
| 9:15 pm - 9:25 pm | Amee George (University of Queensland, St. Lucia, Australia)
"Investigating the mechanism of AngII-mediated EGFR transactivation using a functional genomics (RNA interference) screening approach"
|
| 9:25 pm - 9:30 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Angiotensin: Is there still a need for studying blood pressure regulation? |
| Discussion Leaders: Kirsty Pringle (University of Newcastle, Australia) and Dominik Müller (Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany) |
| 9:00 am - 9:20 am | Matthew A Sparks (Duke University, Durham)
"Impact of vascular smooth muscle cell specific AT1a receptors on blood pressure regulation" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Kelly Putnam (University of Kentucky, Lexington)
"Role of adipocyte-derived angiotensinogen in obesity-induced hypertension and in Ang II-induced vascular diseases" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Rasna Sabharwal (University of Iowa, Iowa City)
"Methionine sulfoxide reductase-A protects against angiotensin II-induced autonomic and cardiac dysfunction, and aortic aneurysms" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 10:40 am | Alexandros Nikolaou (Vrije University Brussel, Belgium)
"IVDE77: A novel novel synthetic Ang IV-analogue for the insulin-regulated aminopeptidase" |
| 10:40 am - 10:45 am | Discussion |
| 10:45 am - 10:55 am | Zhiying Shan (University of Florida, Gainesville)
"Chronic blockade of the NTS AT1R decreases circulating endothelial progenitor-inflammatory cells ratio and exacerbates hypertension in the SHR"
|
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | The impact of angiotensin and its metabolites on target organ function and regeneration |
| Discussion Leaders: Qianchen, Yong (Texas A&M Health Science, Temple) and Lisa Cassis (University of Kentucky, Lexington) |
| 1:30 pm - 1:50 pm | Jusin L Grobe (University of Iowa, Iowa City)
"Control of metabolic rate by brain angiotensins" |
| 1:50 pm - 2:00 pm | Discussion |
| 2:00 pm - 2:10 pm | Wendy Batenburg (Erasmus University Rotterdam, Netherlands)
"The putative (pro)renin receptor blocker HRP(handle region peptide) upregulates endothelium-contractile factors in aliskiren-treated diabetic transgenic (mREN2)27 rats" |
| 2:10 pm - 2:15 pm | Discussion |
| 2:15 pm - 2:25 pm | Alison Bourne (Temple University School of Medicine, Philadelphia)
"Vascular selective ADAM17 silencing prevented medial hypertrophy and perivascular fibrosis induced by angiotensin II infusion" |
| 2:25 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
| 3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |