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Conference Program
 
Cardiac Regulatory Mechanisms
Gordon-Merck Research Seminar
June 9-10, 2012
Colby-Sawyer College
New London, NH
Chair:
Mark J. Kohr

Associate Chair:
Shirin Doroudgar

Related Meeting Information
The Cardiac Regulatory Mechanisms Gordon-Merck Research Seminar was held in conjunction with the Cardiac Regulatory Mechanisms Gordon Research Conference. Please refer to the Cardiac Regulatory Mechanisms GRC web page for more information.

The Gordon Research Seminar on Cardiac Regulatory Mechanisms is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The 2012 Cardiac Regulatory Mechanisms Gordon Research Seminar will encompass many different themes, and will include sessions on "New Frontiers in Excitation-Contraction Coupling" and "Hypertrophy, Failure and Cardioprotection". This forum will facilitate interaction between graduate students, post-doctoral fellows and other scientists, and will foster scientific collaboration. Participants will gain valuable presentation experience and feedback in a collegial atmosphere, and this experience will prepare them to actively participate in the ensuing Cardiac Regulatory Mechanisms Gordon Research Conference. Participants will also gain important insight from the keynote address by Dr. Jeffery Molkentin and a Scientific Writing Workshop, which includes a grant writing panel discussion with Dr. Howard Rockman and Dr. Barbara Casadei and a talk by the Editor-in-Chief of the Journal of Molecular and Cellular Cardiology, Dr. David Eisner. Overall, the 2012 Cardiac Regulatory Mechanisms Gordon Research Seminar will provide graduate students and post-doctoral fellows with an invaluable learning experience that will help to further their careers in research.


Contributors

SATURDAY
1:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Address
Discussion Leader: Shirin Doroudgar (San Diego State University)
3:45 pm - 4:15 pmJeffery D. Molkentin (Howard Hughes Medical Institute)
"Calcium and the regulation of cardiac hypertrophy"
4:15 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session I
6:00 pmDinner
7:30 pm - 9:30 pmNew Frontiers in Excitation-Contraction Coupling
Discussion Leader: Elizabeth Bode (University of Manchester) and Viktoriia Kyrychenko (UMDNJ-NJMS)
7:30 pm - 7:46 pmJerry Curran (The Ohio State University)
"The role of EHD proteins in cardiac excitability and disease"
7:46 pm - 7:54 pmDiscussion
7:54 pm - 8:10 pmPrakash Subramanyam (Columbia University)
"Engineering the composition of L-type (CaV1.2) channels in heart cells using split intein-mediated protein trans-splicing"
8:10 pm - 8:18 pmDiscussion
8:18 pm - 8:34 pmNeha Abrol (Loyola University Chicago)
"The Role of lethal phospholamban R9C mutation in SERCA dysfunction"
8:34 pm - 8:42 pmDiscussion
8:42 pm - 8:58 pmJessica Clarke (University of Manchester)
"The role of Ca buffering and ICa,L in the age associated decrease in Ca transient amplitude in atrial myocytes"
8:58 pm - 9:06 pmDiscussion
9:06 pm - 9:22 pmLars Kaestner (Saarland University)
"Functional and morphological preservation of adult ventricular myocytes in culture"
9:22 pm - 9:30 pmDiscussion
SUNDAY
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amHypertrophy, Heart Failure and Cardioprotection
Discussion Leaders: Cosmo Damiano Del Voscovo (University of Lausanne) and Premi Shekar (University of Kentucky)
9:00 am - 9:16 amFaye Drawnel (Babraham Institute)
"IP3-induced calcium release engages a pro-hypertrophic autoamplifying loop that relieves miR-133a mediated suppression of IP3RII calcium channels"
9:16 am - 9:24 amDiscussion
9:24 am - 9:40 amJason Yang (University of Virginia)
"PKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to β-Adrenergic signaling"
9:40 am - 9:48 amDiscussion
9:48 am - 10:04 amFu Siong Ng (Washington University in St. Louis)
"Accelerated ischemia-induced electrophysiological changes and slower recovery following reperfusion in failing human myocardium"
10:04 am - 10:12 amDiscussion
10:12 am - 10:28 amSwathi Appachi (National Heart Lung and Blood Institute)
"Non-nuclear estrogen receptor activation is protective in cardiac ischemia-reperfusion injury in mice"
10:28 am - 10:36 amDiscussion
10:36 am - 10:52 amMirko Volkers (San Diego State University)
"Cardioprotection by Optimizing mTOR activity"
10:52 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session II
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:45 pmScientific Writing Workshop: Grant Writing & Manuscript Preparation
Discussion Leader: Mark Kohr (Johns Hopkins University)
Grant Writing Panel Discussion: United States and Europe
1:30 pm - 1:40 pmHoward Rockman (Duke University)
"How to write grants that lead to great papers: An Editor's perspective"
1:40 pm - 1:50 pmBarbara Casadei (Oxford University)
"How to write a grant that gets funded"
1:50 pm - 2:10 pmDiscussion
Manuscript Preparation in the Cardiovascular Sciences
2:10 pm - 2:30 pmDavid Eisner (University of Manchester)
"Fraud and impact factors: two ways to mess up science"
2:30 pm - 2:45 pmDiscussion
2:45 pm - 3:00 pmEvaluation Period
Fill out GRS Evaluation Forms
3:00 pmGordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm.

 
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