The Gordon Research Seminar on Signaling by Adhesion Receptors is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.
The meeting will focus on the interface between cell signaling and cell adhesion receptors, drawing from diverse fields including cell and developmental biology, bioengineering, biophysics, biomedical research, and systems biology. This GRS will not only provide an outstanding opportunity for graduate students and post-docs to present their work, receive constructive feedback, network with each other and receive mentoring, but also prepare attendees for the subsequent GRC, enabling higher levels of student participation and leadership throughout the GRC.
|1:00 pm - 5:00 pm||Arrival and Check-in|
|3:30 pm - 3:45 pm||Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair|
|3:45 pm - 4:30 pm||At the site of integrin adhesions|
|3:45 pm - 4:15 pm||Cheng-Han Yu (National University of Singapore)
"Integrin activation triggers contractile movement and subsequent outward translocation of integrin-RGD clusters on supported membranes"
|4:15 pm - 4:30 pm||Discussion|
|4:30 pm - 6:00 pm||Poster Session I (Last names A-M)|
|7:30 pm - 9:30 pm||Adhesion receptor signaling in cell migration|
|Discussion Leaders: Martin Schwartz (Yale School of Medicine) and Rosa Ng (Harvard Medical School)|
|7:30 pm - 7:50 pm||Florian Sulzmaier (University of Hawaii Cancer Center)
"PEA-15 regulates glioblastoma cell migration through RSK2"
|7:50 pm - 8:00 pm||Discussion|
|8:00 pm - 8:20 pm||Leolene Jean (Vanderbilt University)
"Activation of Rac by Asef2 promotes myosin II-dependent contractility to inhibit cell migration on type I collagen"
|8:20 pm - 8:30 pm||Discussion|
|8:30 pm - 8:50 pm||Minggang Zhang (NIAID/NIH)
"Beta2 integrin LFA-1 triggers lytic granule polarization at natural killer cell synapses through ILK, gamma-parvin, and RhoGEF7"
|8:50 pm - 9:00 pm||Discussion|
|9:00 pm - 9:20 pm||Guillaume Jacquemet (University of Manchester)
"Filamin-A and IQGAP1 constrain Rac1 activity at sites of integrin activation via recruitment of RacGAP1"
|9:20 pm - 9:30 pm||Discussion|
|7:30 am - 8:30 am||Breakfast|
|9:00 am - 11:00 am||New approaches to cell adhesion complexes and signaling|
|Discussion Leaders: Martin Humphries (University of Manchester) and Kimberly Stroka (Johns Hopkins University)|
|9:00 am - 9:20 am||Adam Byron (University of Manchester)
"Proteomic analysis of integrin adhesion complexes reveals diverse cellular roles for adhesion signaling"
|9:20 am - 9:30 am||Discussion|
|9:30 am - 9:50 am||Benjamin Bangasser (University of Minnesota)
"Optimality in a motor-clutch cell traction model"
|9:50 am - 10:00 am||Discussion|
|10:00 am - 10:20 am||Michael Bachmann (Karlsruhe Institute of Technology)
"Development and maturation of nascent adhesions visualized with superresolution microscopy"
|10:20 am - 10:30 am||Discussion|
|10:30 am - 10:50 am||Cuc Bach (Children's Hospital at Westmead, Australia)
"The actin-associating protein Tm5NM1 inhibits protein trafficking to focal adhesions"
|10:50 am - 11:00 am||Discussion|
|11:00 am - 12:30 pm||Poster Session II (Last names N-Z)|
|Coffee will be served in the poster area from 11:00 am - 11:30 am|
|1:30 pm - 2:30 pm||Mentorship component: Navigating early career transitions|
|Discussion Leader: Valerie Weaver (University of California, San Francisco)|
|1:30 pm - 2:15 pm||Valerie Weaver (University of California, San Francisco)
|2:15 pm - 2:45 pm||Discussion|
|2:45 pm - 3:00 pm||Evaluation Period|
|Fill out GRS Evaluation Forms|
|3:00 pm||Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm.|
Funding for this conference was made possible [in part] by 1 R13 AI 100533 - 01 from the National Institute of Allergy and Infectious Diseases. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
Funding for this conference was made possible (in part) by 5R13CA133995-03 from the National Cancer Institute. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.