| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
| 6:00 pm | Dinner |
| 7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
| 7:40 pm - 9:30 pm | Keynote Lectures |
| Discussion Leaders: Helen McNeill (Mount Sinai Hospital) and Brian Link (Medical College of Wisconsin)
|
| 7:40 pm - 8:20 pm | Larry Zipursky (University of California - Los Angeles)
"The Molecular Logic of Layer Specific Targeting in the Drosophila Visual System"
|
| 8:20 pm - 8:35 pm | Discussion |
| 8:35 pm - 9:15 pm | Joshua Sanes (Harvard University)
"Laminar and lateral specificity in the retina"
|
| 9:15 pm - 9:30 pm | Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Stem Cell and Proliferation |
| Discussion Leader: Tom Reh (University of Washington) |
| 9:00 am - 9:25 am | Derek van der Kooy (University of Toronto)
"Retinal stem cells"
|
| 9:25 am - 9:30 am | Discussion |
| 9:30 am - 9:55 am | Yoshiki Sasai (RIKEN)
"Self-organization of 3D retinal tissue from ES cells and its mechanism"
|
| 9:55 am - 10:00 am | Discussion |
| 10:00 am - 10:25 am | Muriel Perron (Institute of Neurobiology, University of Paris-Sud)
"The Hippo pathway as a novel player in the signalling network controlling retinal stem cell proliferation"
|
| 10:25 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 11:00 am - 11:25 am | Edward Levine (University of Utah)
"How homeodomain proteins regulate the progenitor program in the mouse retina"
|
| 11:25 am - 11:30 am | Discussion |
| 11:30 am - 11:52 am | Vincent Tropepe (University of Toronto)
"Ontogeny of the zebrafish CMZ and the regulation of life long retinal neurogenesis"
|
| 11:52 am - 12:00 pm | Discussion |
| 12:00 pm - 12:22 pm | Katia Del Rio-Tsonis (Miami University)
"C3a as a potent inducer of chick retina regeneration"
|
| 12:22 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Chromatin and Competence |
| Discussion Leader: Michael Dyer (St. Jude Children's Research Hospital) |
| 7:30 pm - 7:55 pm | Itsuki Ajioka (Tokyo Medical and Dental University)
"The role of chromatin remodeling factor for retinogenesis and retinoblastoma development"
|
| 7:55 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:25 pm | Jessica Treisman (Skirball Institute)
"Determinants of synaptic partner specificity for color-sensitive photoreceptors in Drosophila"
|
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:55 pm | Monica Vetter (University of Utah)
"Epigenetic Regulation of Retinal Neurogenesis"
|
| 8:55 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:25 pm | Jeffrey Gross (University of Texas - Austin)
"Epigenetic regulation of lens development"
|
| 9:25 pm - 9:30 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Glia and Non-Neural Tissue Development |
| Discussion Leaders: Edward Levine (University of Utah) and Tiffany Cook (Cincinnati Children's Hospital) |
| 9:00 am - 9:25 am | Christian Klambt (Universität Münster)
"Migration and cell fate decisions in the eye glia of Drosophila"
|
| 9:25 am - 9:30 am | Discussion |
| 9:30 am - 9:55 am | Iris Salecker (MRC National Institute for Medical Research)
"Epigenetic control of neuroepithelial specification and neurogenesis modes in the Drosophila visual system"
|
| 9:55 am - 10:00 am | Discussion |
| 10:00 am - 10:25 am | Seth Blackshaw (Johns Hopkins University)
"Control of glial specification and function by Lhx2"
|
| 10:25 am - 10:30 am | Discussion |
| 10:30 am | Group Photo / Coffee Break |
| 11:00 am - 11:25 am | Richard Lang (Cincinnati Children's Hospital)
"Light-dependent vascular development"
|
| 11:25 am - 11:30 am | Discussion |
| 11:30 am - 11:55 am | Philip Gage (University of Michigan)
"The homeodomain transcription factor PITX2 is required to establish correct cell lineages and angiogenic privilege in the developing cornea"
|
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:22 pm | David Beebe (Washington University)
"Adhesion to the ECM Between the Optic Vesicle and Lens Mediates Optic Cup Formation"
|
| 12:22 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Circuitry and Synapses |
| Discussion Leader: Pamela Raymond (University of Michigan) |
| 7:30 pm - 7:55 pm | Botond Roska (Friedrich Miescher Institute for Biomedical Research)
"Development of neuronal circuit asymmetry in the retina"
|
| 7:55 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:25 pm | Takahisa Furukawa (Osaka University)
"Molecular control of photoreceptor synapse development"
|
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:55 pm | Lisa Goodrich (Harvard University)
"Amacrine cell dendrite development and the emergence of plexiform layers"
|
| 8:55 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:22 pm | Tudor Badea (National Eye Institute, NIH)
"Role of Brn3 transcription factors in Retinal Ganglion Cell type specification"
|
| 9:22 pm - 9:30 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Morphogenesis and Trafficking, and Emerging Topics in Vision Research |
| Discussion Leader: Don Ready (Purdue University) |
| 9:00 am - 9:25 am | Nic Tapon (Cancer Research UK)
"Control of adherens junction remodeling during retinal development"
|
| 9:25 am - 9:30 am | Discussion |
| 9:30 am - 9:55 am | Ching-Hwa Sung (Weill Medical College of Cornell University)
"The dynamics of mammalian photoreceptor outer segment: genesis, renewal, and its interaction with RPE"
|
| 9:55 am - 10:00 am | Discussion |
| 10:00 am - 10:22 am | Robert Johnston (New York University)
"Controlling stochastic gene expression in the Drosophila retina"
|
| 10:22 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 11:00 am - 11:22 am | Michalis Agathocleous (UT Southwestern Medical Center)
"Metabolic differentiation in the embryonic retina"
|
| 11:22 am - 11:30 am | Discussion |
| 11:30 am - 11:55 am | Harald Junge (University Of Colorado at Boulder)
"Function of TSPAN12 in Norrin/Frizzled-4 signaling and retinal vascular development"
|
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:22 pm | Mark Emerson (Harvard University)
"A Cis-Regulatory Analysis Suggests Distinct Developmental Generation of Cone and Rod Vertebrate Photoreceptors"
|
| 12:22 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
| 7:30 pm - 9:30 pm | Evolution |
| Discussion Leader: Claude Desplan (New York University) |
| 7:30 pm - 7:55 pm | William Jeffery (University of Maryland)
"Regressive Eye Development and Evolution: A View From the Blind Cavefish"
|
| 7:55 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:25 pm | Andrew Tomlinson (Columbia University)
"Antagonistic Notch signaling in Drosophila R7 specification: An evolutionary perspective" |
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:55 pm | David Plachetzi (University Of California - Davis)
"The origins and evolution of the animal phototransduction cascade: new insights from the Cnidaria"
|
| 8:55 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:25 pm | Markus Friedrich (Wayne State University)
"Regressive Eye Development and Evolution: A View From a Cave Beetle"
|
| 9:25 pm - 9:30 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Signaling and Transcription |
| Discussion Leader: Michel Cayouette (IRCM) |
| 9:00 am - 9:25 am | Tom Reh (University of Washington)
"Developmental timing in retinogenesis is controlled by miRNAs and Notch"
|
| 9:25 am - 9:30 am | Discussion |
| 9:30 am - 9:55 am | David Lubensky (University of Michigan - Ann Arbor)
"Emergence of Geometric Order and Cell Identity in the Zebrafish Cone Photoreceptor Mosaic"
|
| 9:55 am - 10:00 am | Discussion |
| 10:00 am - 10:25 am | Erika Bach (New York University School of Medicine)
"The roles of STAT and its targets in Drosophila eye"
|
| 10:25 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 11:00 am - 11:25 am | Valerie Wallace (Ottawa Hospital Research Institute)
"Functional analysis of Hedgehog target genes in the retina"
|
| 11:25 am - 11:30 am | Discussion |
| 11:30 am - 11:55 am | Joseph Corbo (Washington University, St. Louis)
"The cis-regulatory logic of mammalian photoreceptors"
|
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:25 pm | Graeme Mardon (Baylor College of Medicine)
"The Retinal Determination Network and Notch Initiate Photoreceptor Differentiation by Repressing eyeless Expression in the Drosophila eye"
|
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Disease Mechanisms |
| Discussion Leader: Brian Link (Medical College of Wisconsin) |
| 7:30 pm - 7:55 pm | Brian Brooks (NIH)
"The Genetics of Uveal Coloboma"
|
| 7:55 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:22 pm | Sean McCurdy (Toronto Western Hospital)
"Pharmaceutical inactivation of E2f and Cdk activity blocks retinoblastoma initiation"
|
| 8:22 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:52 pm | Shobi Veleri (National Eye Institute, NIH)
"Cc2d2a is essential for cilia and photoreceptor development"
|
| 8:52 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:25 pm | Richard Maas (Harvard University)
"Post-transcriptional regulation of vertebrate lens development"
|
| 9:25 pm - 9:30 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |