Gordon Research Conferences
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Conference Program
 
Carbohydrates
June 16-21, 2013
Mount Snow Resort
West Dover, VT

Application Deadline
The application deadline for this meeting was May 19, 2013. You may still submit an application. However, it will only be considered by the Conference Chair if more seats become available due to cancellations.

The science of carbohydrates has been studied for well over one hundred years, but it is only in the last few that the myriad roles played by cellular sugars in normal development and disease have been fully appreciated. This importance of carbohydrates is succinctly illustrated in the recent commissioned report by the National Academy of Sciences that outlines a roadmap for the future of glycoscience research and means to reach some of those goals. The 2013 Gordon Research Conference on Carbohydrates will bring together some of the most important players in transformative glycoscience, and serve as a forum for discussions on progress in those areas of glycoscience that are most in need of improvement: Glycan synthesis, analysis, detection, structure and informatics. The meeting will highlight the work of both established and younger glycoscientists through a nearly equal number of invited and short talks, including rapid "poster" talks to direct the audience to work presented at each of the poster sessions. Included will be a session entitled "Lessons from the Consortium for Functional Glycomics" that will bring together group leaders form the various core laboratories that comprised the consortium and discuss ways forward for the future of the technology that evolved from that experiment. The goal of this meeting will be to bring together both the primary players and those up and coming in the field to consider the most critical aspects of glycoscience and as a result make informed suggestions as to the way forward for the entire field.


Contributors

SUNDAY
2:00 pm - 9:00 pmArrival and Check-in (Office Closed 6:00 pm - 7:00 pm)
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmChemical Glycobiology
Discussion Leader: Jeff Gildersleeve (National Cancer Institute at Frederick)
7:40 pm - 8:05 pmAmit Basu (Brown University)
"Chemical Glycobiology of Pollen Tube Extension"
8:05 pm - 8:15 pmDiscussion
8:15 pm - 8:40 pmDavid Jakeman (Dalhousie U)
"Carbohydrate phosphonates, multi-functional enzyme probes"
8:40 pm - 8:50 pmDiscussion
8:50 pm - 9:15 pmDavid Vocadlo (Simon Fraser U)
"New chemical tools for studying glycosylation in cells"
9:15 pm - 9:25 pmDiscussion
9:25 pm - 9:30 pmTBA (Poster Highlight talk)
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmLessons from the CFG (Consortium for Functional Glycomics)
Discussion Leader: Joe Barchi (National Cancer Institute at Frederick)
9:00 am - 9:20 amPamela Marino (NIGMS)
9:20 am - 9:25 amDiscussion
9:25 am - 9:50 amJames Paulson (Scripps Research Institute)
"Decoding the glycome: A central paradigm of the CFG"
9:50 am - 10:00 amDiscussion
10:00 am - 10:25 amGroup Photo / Coffee Break
10:25 am - 10:50 amAnne Dell (Imperial College)
"Glycosylation of mouse and human immune cells: insights emerging from glycomics analysis"
10:50 am - 11:00 amDiscussion
11:00 am - 11:25 amDavid Smith (Emory U.)
"Application of Glycan Microarrays to Deciphering the Structure and Function of the Human Glycome"
11:25 am - 11:35 amDiscussion
11:35 am - 12:00 pmRahul Raman (MIT)
"Informatics for Glycomics at the CFG"
12:00 pm - 12:10 pmDiscussion
12:10 pm - 12:25 pmTBA (Poster Talk)
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmCarbohydrate Synthesis and Biosynthesis
Discussion Leader: George O'Doherty (Northeastern University)
7:30 pm - 7:55 pmHung-wen (Ben) Liu (University of Texas)
"Exploiting sulfur carrier proteins from primary metabolism for 2-thiosugar biosynthesis"
7:55 pm - 8:05 pmDiscussion
8:05 pm - 8:30 pmJaquelyn Gervay-Hague (University of California, Davis)
"Recent Studies on Glycolipid Profiling"
8:30 pm - 8:40 pmDiscussion
8:40 pm - 8:50 pmTBA (Poster Talk)
8:50 pm - 8:55 pmDiscussion
8:55 pm - 9:20 pmLinda Hsieh-Wilson (Cal Tech)
"Using Chemistry to Discover Carbohydrate Mechanisms in Biology and Disease"
9:20 pm - 9:30 pmDiscussion
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmCarbohydrate Immunology and Immunotherapy
Discussion Leader: TBA
9:00 am - 9:25 amPeter Andreana (University of Toledo)
"PS A1 as a Covalent Adjuvant in Immune Stimulation"
9:25 am - 9:35 amDiscussion
9:35 am - 9:45 amTBA (Poster Talk)
9:45 am - 9:50 amDiscussion
9:50 am - 10:15 amKate Rittenhouse-Olson (University of Buffalo)
"Unique immunization strategies for Thomsen Friedenreich Antigen"
10:15 am - 10:25 amDiscussion
10:25 am - 10:55 amCoffee Break
10:55 am - 11:05 amTBA (Poster Talk)
11:05 am - 11:10 amDiscussion
11:10 am - 11:35 amHorst Kunz (University of Mainz)
"Synthetic Antitumor Vaccines - an Interplay of Carbohydrate and Peptide Antigen Structures"
11:35 am - 11:45 amDiscussion
11:45 am - 11:55 amTBA (Poster Highlight Talks)
11:55 am - 12:20 pmLai-Xi Wang (University of Maryland)
"Synthetic Carbohydrate Antigens for HIV Vaccine Design"
12:20 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmGlycans and Natural Products
Discussion Leader: TBA
7:30 pm - 7:55 pmJurgen Rohr (University of Kentucky)
"Enzymatic Total Syntheses of TDP-deoxysugars and Their Use for Studying Glycosyltransfer Reactions of Antitumor Antibiotic Biosyntheses"
7:55 pm - 8:05 pmDiscussion
8:05 pm - 8:30 pmRodrigo Andrade (Temple University)
"Total Synthesis and Biological Evaluation of Desmethyl Macrolide Antibiotics"
8:30 pm - 8:40 pmDiscussion
8:40 pm - 8:50 pmTBA (Poster Talk)
8:50 pm - 8:55 pmDiscussion
8:55 pm - 9:20 pmJon Thorson (University of Kentucky)
"New Strategies for Natural Product Discovery and Diversification"
9:20 pm - 9:30 pmDiscussion
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmMolecular Recognition and Structure
Discussion Leader: TBA
9:00 am - 9:25 amRobert Woods (University of Georgia)
"Computational screening of virtual glycan arrays: a new tool for specificity prediction and validation"
9:25 am - 9:35 amDiscussion
9:35 am - 9:45 amTBA (Poster Talk)
9:45 am - 9:50 amDiscussion
9:50 am - 10:15 amDev Arya (Clemson University)
"Shape Recognition of Nucleic Acids by Carbohydrates"
10:15 am - 10:25 amDiscussion
10:25 am - 10:55 amCoffee Break
10:55 am - 11:05 amTBA (Poster Talk)
11:05 am - 11:10 amDiscussion
11:10 am - 11:35 amChang-Chun Lin (University of Calgary)
"Targeting Clostridium Difficile Toxins: Challenges and Recent Developments"
11:35 am - 11:45 amDiscussion
11:45 am - 11:55 amTBA (Poster Talk)
11:55 am - 12:00 pmDiscussion
12:00 pm - 12:10 pmTBA (Poster Talk)
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:25 pmTBA (Poster Talk)
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmGlycosylation and Anomeric Chemistry
Discussion Leader: TBA
7:30 pm - 7:55 pmScott Rychnovsky (University of California Irvine)
"Reactivity next to heteroatoms: anomeric effects beyond carbohydrates"
7:55 pm - 8:05 pmDiscussion
8:05 pm - 8:30 pmToshiki Nokami (Tottori University)
"Reactivity next to heteroatoms: anomeric effects beyond carbohydrates"
8:30 pm - 8:40 pmDiscussion
8:40 pm - 8:50 pmTBA (Poster Talk)
8:50 pm - 8:55 pmDiscussion
8:55 pm - 9:20 pmKeith Woerpel (New York University)
"Electronic Effects and the Stereochemical Courses of Reactions of Oxocarbenium Ions"
9:20 pm - 9:30 pmDiscussion
THURSDAY
7:30 am - 8:30 amBreakfast
8:30 am - 9:00 amBusiness Meeting
Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair
9:00 am - 12:30 pmEnzymes in Glycan Synthesis
Discussion Leader: TBA
9:00 am - 9:25 amKelley Moremen (University of Georgia)
"Production and use of mammalian glycosylation enzymes for enzymatic and structural studies"
9:25 am - 9:35 amDiscussion
9:35 am - 9:45 amTBA (Poster Talk)
9:45 am - 9:50 amDiscussion
9:50 am - 10:15 amXi Chen (University of California Davis)
"Chemoenzymatic synthesis of carbohydrates and glycoconjugates"
10:15 am - 10:25 amDiscussion
10:25 am - 10:55 amCoffee Break
10:55 am - 11:05 amTBA (Poster Talk)
11:05 am - 11:10 amDiscussion
11:10 am - 11:35 amRobert Linhardt (Renssalear Polytechnic University)
"Chemoenzymatic synthesis of heparins"
11:35 am - 11:45 amDiscussion
11:45 am - 11:55 amTBA (Poster Talk)
11:55 am - 12:00 pmDiscussion
12:00 pm - 12:10 pmTBA (Poster Talk)
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:25 pmTBA (Poster Talk)
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmNanomaterials, Sensors and Arrays
Discussion Leader: TBA
7:30 pm - 7:55 pmTheresa Reineke (University of Minnesota)
"Sugar-coated nanocomplexes: designed block copolymers for therapeutic delivery"
7:55 pm - 8:05 pmDiscussion
8:05 pm - 8:30 pmXuewei Liu (Nanyang Technological University)
"Glycosciences: From Synthetic Methods to Glycobiology"
8:30 pm - 8:40 pmDiscussion
8:40 pm - 8:50 pmTBA (Poster Talk)
8:50 pm - 8:55 pmDiscussion
8:55 pm - 9:20 pmNicola Pohl (Indiana University)
"Challenges in Carbohydrate Library Synthesis"
9:20 pm - 9:30 pmDiscussion
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDeparture

Last Updated: May 23, 2013
 
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