| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
| 6:00 pm | Dinner |
| 7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
| 7:40 pm - 9:30 pm | Circadian control of output, DNA repair (cancer) and physiology |
| Discussion Leader: Marina Antoch (Roswell Park) |
| 7:40 pm - 8:00 pm | Michael Brunner (Heidelberg) |
| 8:00 pm - 8:05 pm | Discussion |
| 8:05 pm - 8:25 pm | Aziz Sancar (UNC Chapel Hill) |
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Mukesh Jain (Case Western Reserve) |
| 8:50 pm - 8:55 pm | Discussion |
| 8:55 pm - 9:15 pm | TBA (Selected from GRS) |
| 9:15 pm - 9:20 pm | Discussion |
| 9:20 pm - 9:30 pm | General Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Systems vs. autonomous control of the clock |
| Discussion Leader: Hiroki Ueda (Riken) |
| 9:00 am - 9:20 am | Ravi Allada (Northwestern)
"Neural clocks in Drosophila" |
| 9:20 am - 9:25 am | Discussion |
| 9:25 am - 9:45 am | Erik Herzog (Wash. U)
"GABA and VIP: A Yin-yang couple for circadian synchrony" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am | Group Photo / Coffee Break |
| 10:20 am - 10:45 am | Sato Honma (Hokkaido Univ)
"The circadian system in the SCN; genes, development and environments" |
| 10:45 am - 10:50 am | Discussion |
| 10:50 am - 11:10 am | Maria Ceriani (Fundacion Instituto Leloir Buenos Aires)
"Circadian period integrates network information through activation of the BMP signaling pathway" |
| 11:10 am - 11:15 am | Discussion |
| 11:15 am - 11:35 am | Michael Hastings (MRC LMB Cambridge UK)
"Analysis and manipulation of cell-autonomous and network-level circadian pacemaking in the suprachiasmatic nucleus" |
| 11:35 am - 11:40 am | Discussion |
| 11:40 am - 12:00 pm | TBA (Selected from GRS) |
| 12:00 pm - 12:05 pm | Discussion |
| 12:05 pm - 12:20 pm | TBA (Hot Topic talk) |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Entrainment: light, temperature, food and other entraining molecules |
| Discussion Leader: Amita Sehgal (UPenn) |
| 7:30 pm - 7:50 pm | Ueli Schibler (Geneva)
"Identification of circadian signaling pathways by synthetic tandem repeat promoter (STAR-PROM) screening" |
| 7:50 pm - 7:55 pm | Discussion |
| 7:55 pm - 8:15 pm | Samer Hattar (Hopkins)
"From molecules to circuits to behavior: how light influences physiology" |
| 8:15 pm - 8:20 pm | Discussion |
| 8:20 pm - 8:40 pm | Joke Meijer (Leiden Univ Medical Center Holland)
"Light responsiveness and adaptive significance of the circadian system" |
| 8:40 pm - 8:45 pm | Discussion |
| 8:45 pm - 9:05 pm | Charlotte Helfrich-Förster (Universitaet Wuerzburg)
"Role of external and internal photoreceptors in timing Drosophila's daily activity" |
| 9:05 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:25 pm | TBA (Hot Topic talk) |
| 9:25 pm - 9:30 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Clock mechanisms: transcription, protein turnover, structure, and post-transcriptional mechanisms |
| Discussion Leader: Paul Hardin (Texas A&M) |
| 9:00 am - 9:20 am | Joseph Takahashi (UT Southwestern)
"Transcriptional architecture of the circadian clock in mammals" |
| 9:20 am - 9:25 am | Discussion |
| 9:25 am - 9:45 am | Charles Weitz (Harvard)
"Analysis of the PERIOD complex of the mammalian circadian clock" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:10 am | Jay Dunlap (Dartmouth)
"Genetic and molecular analysis of the Neurospora clock" |
| 10:10 am - 10:15 am | Discussion |
| 10:15 am | Coffee Break |
| 10:45 am - 11:05 am | Felix Naef (École Polytechnique Fédérale De Lausanne)
"Mechanisms of phase-specific circadian transcription in mouse liver" |
| 11:05 am - 11:10 am | Discussion |
| 11:10 am - 11:30 am | Achim Kramer (Charité Berlin)
"Posttranscriptional control of mammalian circadian rhythms" |
| 11:30 am - 11:35 am | Discussion |
| 11:35 am - 11:50 am | TBA (Hot Topic talk) |
| 11:50 am - 11:55 am | Discussion |
| 11:55 am - 12:10 pm | TBA (Hot Topic talk) |
| 12:10 pm - 12:15 pm | Discussion |
| 12:15 pm - 12:30 pm | General Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Non-transcriptional-translational oscillator mechanisms |
| Discussion Leader: Carl Johnson (Vanderbilt) |
| 7:30 pm - 7:55 pm | Akhilesh Reddy (Univ. Cambridge)
"Redox and metabolic oscillations in the clockwork" |
| 7:55 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:25 pm | Susan Golden (UC San Diego)
"Intrinsic input and output functions of the Kai oscillator of cyanobacteria" |
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:55 pm | Erin O'Shea (Harvard)
"Timekeeping with a Three-Protein Circadian Clock" |
| 8:55 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:25 pm | John O'Neill (Univ Cambridge)
"Circadian rhythms of haemoglobin auto-oxidation in vitro and in vivo" |
| 9:25 pm - 9:30 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Epigenetics and chromatin with an emphasis on aging |
| Discussion Leader: TBA |
| 9:00 am - 9:20 am | Paolo Sassone-Corsi (UC Irvine) and Steve Brown (Univ. Zurich)
"Neural networking and epigenetics within the suprachiasmatic nucleus" |
| 9:20 am - 9:25 am | Discussion |
| 9:25 am - 9:45 am | Jürgen Ripperger (Univ Fribourg Switzerland)
"Role of circadian transcription factors in aging"
|
| 9:45 am - 9:55 am | Discussion |
| 9:55 am - 10:10 am | Leonard Guarente (MIT)
"Aging-sensitive control of central circadian rhythm by SIRT1" |
| 10:10 am - 10:15 am | Discussion |
| 10:15 am | Coffee Break |
| 10:45 am - 11:05 am | Satchidananda Panda (Salk) |
| 11:05 am - 11:10 am | Discussion |
| 11:10 am - 11:30 am | Paloma Mas (Instituto de Biologia Molecular de Barcelona)
"Chromatin and the Arabidopsis circadian clock: a question of time" |
| 11:30 am - 11:35 am | Discussion |
| 11:35 am - 11:55 am | TBA (Selected from GRS) |
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:20 pm | TBA (Selected from GRS) |
| 12:20 pm - 12:25 pm | Discussion |
| 12:25 pm - 12:30 pm | General Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
| 7:30 pm - 9:30 pm | Plants including agriculturally or industrially interesting organisms |
| Discussion Leader: TBA |
| 7:30 pm - 7:50 pm | Andrew Millar (Univ. Edinburgh)
"Models and infrastructure for systems chronobiology" |
| 7:50 pm - 8:10 pm | Steve Kay (USC)
"Circadian networks in higher plants" |
| 8:10 pm - 8:15 pm | Combined Discussion |
| 8:15 pm - 8:35 pm | Takeshi Izawa (National Institute of Agrobiological Sciences)
"Clock and photoperiodism in rice and productivity" |
| 8:35 pm - 8:40 pm | Discussion |
| 8:40 pm - 9:00 pm | Alison Smith (John Innes Center)
"Timing starch consumption prevents starvation in Arabidopsis plants" |
| 9:00 pm - 9:05 pm | Discussion |
| 9:05 pm - 9:25 pm | Daniel Forger (Univ Michigan)
"Supermodels see the light of day: How high performance computing can help the next generation of circadian research"
|
| 9:25 pm - 9:30 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am - 9:00 am | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
| 9:00 am - 12:30 pm | Metabolic diseases II: metabolic syndrome, diabetes and aging |
| Discussion Leader: TBA |
| 9:00 am - 9:20 am | Carla Green (Univ of Texas Southwestern Medical Center)
"Circadian post-transcriptional control of metabolism" |
| 9:20 am - 9:25 am | Discussion |
| 9:25 am - 9:45 am | Joe Bass (Northwestern)
"Circadian Control of Bioenergetics and Fuel Selection in Mice" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:10 am | Gad Asher (Weizmann Institute of Science)
"A cross talk between metabolism and circadian rhythmicity" |
| 10:10 am - 10:15 am | Discussion |
| 10:15 am | Coffee Break |
| 10:45 am - 11:05 am | Masashi Yanagisawa (UT Southwestern Medical Center/HHMI and Univ of Tsukuba)
"Forward genetic analysis of sleep in ENU-mutagenized mice: Identification of pedigrees with heritable sleep/wake abnormalities" |
| 11:05 am - 11:10 am | Discussion |
| 11:10 am - 11:30 am | TBA (Hot Topic talk) |
| 11:30 am - 11:35 am | Discussion |
| 11:35 am - 11:55 am | TBA (Selected from GRS) |
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:20 pm | TBA (Selected from GRS) |
| 12:20 pm - 12:25 pm | Discussion |
| 12:25 pm - 12:30 pm | General Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Sleep |
| Discussion Leader: Mike Young (Rockefeller) |
| 7:30 pm - 7:45 pm | Mehdi Tafti (Lausanne) and Amita Sehgal (UPenn) |
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 8:10 pm | Paul Shaw (Washington Univ of St. Louis) |
| 8:10 pm - 8:15 pm | Discussion |
| 8:15 pm - 8:35 pm | Leslie Griffith (Brandeis Univ)
"Peptidergic regulation of sleep in Drosophila" |
| 8:35 pm - 8:40 pm | Discussion |
| 8:40 pm - 9:00 pm | Simon Archer (Surrey, UK)
"Sleep and circadian regulation of gene expression" |
| 9:00 pm - 9:05 pm | Discussion |
| 9:05 pm - 9:25 pm | Paul Franken (Univ Lausanne)
"Sleep homeostasis and circadian rhythms: shared molecular pathways?" |
| 9:25 pm - 9:30 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |