Gordon Research Conferences
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Conference Program
 
Collagen
In the Context of Matrix, Cells and Regenerative Medicine
July 14-19, 2013
Colby-Sawyer College
New London, NH
Chair:
Karl Kadler

Vice Chair:
Collin M. Stultz

Application Deadline
Applications for this meeting must be submitted by June 16, 2013. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.
Related Meeting Information
The Collagen Gordon Research Conference will be held in conjunction with the Collagen Gordon Research Seminar. Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Please refer to the Collagen GRS web page for more information.

Program Overview

Collagen is the most abundant macromolecule of the extracellular matrix and the principal determinant of tissue strength. Understanding how cells synthesize, organize, regulate and interact with collagen-rich matrices is therefore central to biological processes such as development, tissue homeostasis, ageing, disease, injury and repair. The Collagen Gordon Research Conference (GRC) is the premiere meeting in the collagen research field and provides a collegial atmosphere for scientists from academia, medicine and industry to discuss all aspects of collagen-matrix research. The 2013 Gordon Research Conference on ‘Collagen’ will emphasize the broad scope of collagen research. The Program will include sessions on Emerging Technologies, Collagen Biosynthesis and Assembly, Interactions, Receptors and Signaling, Developmental Mechanisms, Genetic Mechanisms, Collagen Regulation, Stem Cells, Repair and Regenerative Medicine, and Mechanobiology.

The sessions will be chaired by leaders in the field who will assist the Organizing Committee in putting together a program to encourage participation from leading investigators, young research fellows, students and post-docs. Some poster presentations will be selected for short talks. Poster presentations and informal gatherings in the afternoon and evenings will encourage scientists to discuss and debate collagen-ECM research. The conference will begin on Sunday evening with a session focused on discussing the emerging technologies in collagen and cell-matrix research. The conference will conclude on Thursday evening with a session focused on identifying the future direction of collagen-matrix research.

Gordon Research Seminar

The 2011 Collagen GRC was associated with the first ever Collagen Gordon Research Seminar (GRS), which featured talks exclusively from graduate students and postdoctoral fellows. The GRS was voted by the participants to be a major success and will be repeated in 2013. The 2013 Collagen GRS will be a 2-day symposium, opened by a keynote talk by Professor Leena Bruckner-Tuderman, that will provide a venue for young scientists to present and discuss their current work, learn from one another, and establish collaborative networks. Graduate students and postdoctoral fellows are strongly encouraged to attend both the GRS and GRC. Three speakers from the GRS will be selected to give platform presentations in the main GRC meeting.


Contributors

SUNDAY
2:00 pm - 9:00 pmArrival and Check-in (Office Closed 6:00 pm - 7:00 pm)
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff and Chair Karl Kadler (University of Manchester)
7:40 pm - 9:30 pmEmerging Technologies in Cell-Matrix Research
7:40 pm - 8:00 pmDiscussion Leader: John Bateman (Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Australia)
"Introductory Remarks"
8:00 pm - 8:10 pmDiscussion
8:10 pm - 8:30 pmMartin Humphries (University of Manchester, UK)
"What's in an adhesion complex, and how does it work?"
8:30 pm - 8:40 pmDiscussion
8:40 pm - 9:00 pmMelinda Duer (University of Cambridge, UK)
"Heavy mice and lighter things: using NMR spectroscopy to elucidate molecular structures in tissues"
9:00 pm - 9:10 pmDiscussion
9:10 pm - 9:25 pmTBA (Selected from Submitted Abstracts or GRS)
9:25 pm - 9:30 pmDiscussion
9:30 pm - 10:30 pmReception
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmCollagen Biosynthesis, Structure and Assembly
9:00 am - 9:20 amDiscussion Leader: David Hulmes (Institute for the Biology and Chemistry of Proteins, Lyon, France)
"Introductory Remarks"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amDavid Eyre (University of Washington, Seattle)
"Prolyl 3-hydroxylation, molecular assembly and cross-linking"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amMichael Rape (University of California, Berkeley)
"Ubiquitin-dependent regulation of collagen secretion"
10:20 am - 10:30 amDiscussion
10:30 am - 10:55 amCoffee Break
10:55 am - 11:15 amTak Mak (University of Toronto, Canada)
"Regulation of collagen synthesis by onco-metabolite 2-hydroxyglutarate"
11:15 am - 11:25 amDiscussion
11:25 am - 11:45 amMaria Antonietta De Matteis (Telethon Institute of Genetics and Medicine, Napes, Italy)
"Role of TRAPP complex in procollagen trafficking"
11:45 am - 11:55 amDiscussion
11:55 am - 12:10 pmTBA (Selected from Submitted Abstracts or GRS)
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:25 pmTBA (Selected from Submitted Abstracts or GRS)
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmCollagen-Protein Interactions and Signaling
7:30 pm - 7:50 pmDiscussion Leader: Hilary Ashe (University of Manchester, UK)
"Introductory Remarks"
7:50 pm - 8:00 pmDiscussion
8:00 pm - 8:20 pmAmy Bradshaw (Medical University of South Carolina)
"Procollagen processing in hearts and periodontal ligament - collagen-binding proteins that affect fibril assembly and deposition"
8:20 pm - 8:30 pmDiscussion
8:30 pm - 8:50 pmJohanna Myllyharju (University of Oulu, Finland)
"Collagen prolyl 4-hydroxylases in skeletogenesis"
8:50 pm - 9:00 pmDiscussion
9:00 pm - 9:10 pmTBA (Selected from Submitted Abstracts or GRS)
9:10 pm - 9:15 pmDiscussion
9:15 pm - 9:25 pmTBA (Selected from Submitted Abstracts or GRS)
9:25 pm - 9:30 pmDiscussion
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmDevelopmental Biology of the Matrix
9:00 am - 9:20 amDiscussion Leader: Ronen Schweitzer (Shriners Research Center, Portland, OR)
"Introductory Remarks"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amElazar Zelzer (Weizmann Institute of Science, Israel)
"Building the bone-tendon attachment unit"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amDavid Birk (University of South Florida)
"Regulation of extracellular matrix assembly during development"
10:20 am - 10:30 amDiscussion
10:30 am - 10:55 amGroup Photo / Coffee Break
10:55 am - 11:15 amDelphine Duprez (Université Pierre et Marie Curie, Paris)
"Transcription and growth factors during tendon formation and repair"
11:15 am - 11:25 amDiscussion
11:25 am - 11:45 amAudrey McAlinden (Washington University, St. Louis)
"Mis-expression of embryonic Col2a1 isoforms affects cartilage matrix assembly and post-natal bone development"
11:45 am - 11:55 amDiscussion
11:55 am - 12:10 pmTBA (Selected from Submitted Abstracts or GRS)
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:25 pmTBA (Selected from Submitted Abstracts or GRS)
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmGenetic Mechanisms of Disease
7:30 pm - 7:50 pmDiscussion Leader: Leena Bruckner-Tuderman (Freiburg Institute for Advanced Studies)
"Introductory Remarks"
7:50 pm - 8:00 pmDiscussion
8:00 pm - 8:20 pmCristina Has (University of Freiburg, Germany)
"Focal adhesions and skin fragility disorders"
8:20 pm - 8:30 pmDiscussion
8:30 pm - 8:50 pmQing Jun Meng (University of Manchester, UK)
"Circadian rhythms of matrix-secreting cells"
8:50 pm - 9:00 pmDiscussion
9:00 pm - 9:10 pmTBA (Selected from Submitted Abstracts or GRS)
9:10 pm - 9:15 pmDiscussion
9:15 pm - 9:25 pmTBA (Selected from Submitted Abstracts or GRS)
9:25 pm - 9:30 pmDiscussion
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmCollagen Regulation and Dysregulation
9:00 am - 9:20 amDiscussion Leader: Sergey Leikin (National Institute of Child Health & Human Development, NIH)
"Introductory Remarks"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amPeter Byers (University of Washington, Seattle)
"Lessons learned: cis- and trans-acting effects on collagen production and structure identified from heritable disorders"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amKazuhiro Nagata (Kyoto Sangyo University, Japan)
"Regulation of collagen synthesis by Hsp47 and P4H in combination with specific inhibitors"
10:20 am - 10:30 amDiscussion
10:30 am - 10:55 amCoffee Break
10:55 am - 11:15 amJoan Marini (NICHD, NIH)
"Identification of a causative mutation for bone dysplasia"
11:15 am - 11:25 amDiscussion
11:25 am - 11:45 amGiorgio Galli (Boston Children's Hospital)
"Prdm5-dependent regulation of collagen genes transcription"
11:45 am - 11:55 amDiscussion
11:55 am - 12:10 pmTBA (Selected from Submitted Abstracts or GRS)
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:25 pmTBA (Selected from Submitted Abstracts or GRS)
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair
7:30 pm - 9:30 pmStem Cells, Repair and Regenerative Medicine
7:30 pm - 7:50 pmDiscussion Leader: Pamela G. Robey (NIDCR, NIH)
"Introductory Remarks"
7:50 pm - 8:00 pmDiscussion
8:00 pm - 8:20 pmFiona Watt (King's College London, UK)
"Dermal remodelling mediated by epidermal signals"
8:20 pm - 8:30 pmDiscussion
8:30 pm - 8:50 pmMatthias Lutolf (Swiss Federal Institute of Technology Lausanne (EPFL))
"Deciphering stem cell-ECM interactions using artificial niches"
8:50 pm - 9:00 pmDiscussion
9:00 pm - 9:10 pmTBA (Selected from Submitted Abstracts or GRS)
9:10 pm - 9:15 pmDiscussion
9:15 pm - 9:25 pmTBA (Selected from Submitted Abstracts or GRS)
9:25 pm - 9:30 pmDiscussion
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmMatrix Mechanobiology
9:00 am - 9:20 amDiscussion Leader: Boris Hinz (University of Toronto)
"Introductory Remarks"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amJanine Erler (BRIC, University of Copenhagen)
"Lysyl oxidases in cancer progression"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amMichael Kjaer (Bispebjerg Hospital, Copenhagen)
"Mechanical loading and collagen turnover in tendon and skeletal muscle - how dynamic is it?"
10:20 am - 10:30 amDiscussion
10:30 am - 10:55 amCoffee Break
10:55 am - 11:15 amDennis Discher (University of Pennsylvania)
"From matrix to nucleus - Scaling results in polymer biophysics"
11:15 am - 11:25 amDiscussion
11:25 am - 11:45 amValerie Weaver (UC Berkeley/UCSF)
11:45 am - 11:55 amDiscussion
11:55 am - 12:10 pmTBA (Selected from Submitted Abstracts or GRS)
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:25 pmTBA (Selected from Submitted Abstracts or GRS)
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmFuture Directions of Collagen Matrix Research
7:30 pm - 7:50 pmDiscussion Leader: Collin Stultz (Harvard-MIT Division of Health Sciences and Technology)
"Introductory Remarks"
7:50 pm - 8:00 pmDiscussion
8:00 pm - 8:20 pmNatalia Nieto (Mount Sinai School of Medicine, NYC)
"Osteopontin, collagen and liver fibrosis"
8:20 pm - 8:30 pmDiscussion
8:30 pm - 8:50 pmMarkus Buehler (Massachusetts Institute of Technology)
"In silico mechanobiology of collagen: mutations, defects and mechanics"
8:50 pm - 9:00 pmDiscussion
9:00 pm - 9:10 pmTBA (Selected from Submitted Abstracts or GRS)
9:10 pm - 9:15 pmDiscussion
9:15 pm - 9:25 pmTBA (Selected from Submitted Abstracts or GRS)
9:25 pm - 9:30 pmDiscussion
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDeparture

Last Updated: February 28, 2013
 
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