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Dendrites: Molecules, Structure & Function
May 19-24, 2013
Les Diablerets Conference Center
Les Diablerets, Switzerland
Chairs:
Rachel Wong & Steven Siegelbaum

Vice Chairs:
Jeffrey Magee & Hollis Cline
Related Meeting Information
The Dendrites: Molecules, Structure & Function Gordon Research Conference was held in conjunction with the Dendrites: Molecules, Structure & Function Gordon Research Seminar. Please refer to the Dendrites: Molecules, Structure & Function GRS web page for more information.

Dendrites play a central role in neuronal information processing by integrating thousands of synaptic inputs to generate a meaningful action potential output. Recent advances in molecular, electrophysiological and in vivo imaging techniques have led to a rapid enhancement in our understanding of the mechanisms that shape dendritic structure, function and connectivity. Such multifaceted approaches have further demonstrated the extent to which dendrite structure and function may undergo plastic changes that contribute to development, learning and neurodegenerative disease. This Gordon conference will bring together researchers whose latest findings help clarify how the molecular and cellular properties of dendrites enable them to perform complex computations important for sensory processing and higher cognitive function. The conference will be of interest to researchers and students in neuroscience, as well as to anyone interested in normal and abnormal brain function.

Contributors
SUNDAY
4:00 pm - 8:00 pmArrival and Check-in (Check-in Desk Closed 6:00 pm - 7:45 pm)
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmKeynote address
7:40 pm - 7:50 pm Introduction: Steven Siegelbaum (HHMI/Columbia Univ.) and Rachel Wong (Univ. Washington)
7:50 pm - 8:50 pm Bert Sakmann (Max-Planck Inst. Florida)
"In vivo and in silico single and shared input spine activation in different layers of rodent vibrissal cortex"
8:50 pm - 9:00 pm Discussion
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmTrafficking of channels, receptors and mRNA
Discussion Leader: Karen Zito (Univ. California Davis)
9:00 am - 9:30 am Casper Hoogenraad (Utrecht Univ.)
"Controlling neuronal transport - motor-adaptor proteins steer mitochondrial trafficking to dendrites"
9:30 am - 9:40 am Discussion
9:40 am - 10:10 am Linda Van Aelst (Cold Spring Harbor Lab)
"Rho-linked genes in neuronal development and disease"
10:10 am - 10:20 am Discussion
10:20 am Coffee Break
10:50 am - 11:05 am Nathalie Higgs (Univ. College London)
"Regulation of dendritic morphogenesis by Miro1-dependent mitochondrial transport"
11:05 am - 11:10 am Discussion
11:10 am - 11:25 am Robert Cudmore (Johns Hopkins Univ.)
"Imaging AMPA receptor trafficking and regulation in vivo"
11:25 am - 11:30 am Discussion
11:30 am - 12:15 pm Alexander M. Cruickshank Lecture: Erin Schuman (Max Planck Inst. Frankfurt)
"Translation in Dendrites"
12:15 pm - 12:30 pm Discussion
12:30 pmGroup Photo / Lunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session I
5:30 pm - 7:30 pmRegulation of dendritic and synaptic organization
Discussion Leader: Jackie Schiller (Technion Israel Inst. of Technology)
5:30 pm - 6:00 pm Yuji Ikegaya (Univ. Tokyo)
"Functional imaging of spatiotemporal patterns of dendritic activity"
6:00 pm - 6:10 pm Discussion
6:10 pm - 6:40 pm Adam Carter (New York Univ.)
"Subcellular synaptic connectivity"
6:40 pm - 6:50 pm Discussion
6:50 pm - 7:05 pm Kazuo Emoto (Osaka Bioscience Inst, Japan)
"The role of compartmentalized calcium signaling in dendrite development and remodeling"
7:05 pm - 7:10 pm Discussion
7:10 pm - 7:25 pm Amy Ghiretti (Brandeis Univ.)
"The activity-dependent GTPase Rem2 is a negative regulator of dendritic complexity"
7:25 pm - 7:30 pm Discussion
8:00 pmDinner
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmIon channels and the regulation of dendritic function
Discussion Leader: Jeff Magee (HHMI Janelia Farm)
9:00 am - 9:30 am Stefan Remy (DZNE, Bonn)
"Altered dendritic synaptic integration and input/output coupling in mouse models of Alzheimer's disease"
9:30 am - 9.40 am Discussion
9:40 am - 10:10 am Jackie Schiller (Technion Israel Inst. of Technology)
"Nonlinear dendritic processing in layer 4 spiny stellate neurons in vitro and in vivo"
10:10 am - 10:20 am Discussion
10:20 am Coffee Break
10:50 am - 11:20 am Dan Johnston (Univ. Texas Austin)
"Temporal synchrony in CA1 pyramidal neurons"
11:20 am - 11:30 am Discussion
11:30 am - 11:45 am Christine Grienberger (Technical Univ. Munich)
"Dendritic calcium spikes underlie complex burst firing in CA1 hippocampal neurons in vivo"
11:45 am - 11:50 am Discussion
11:50 am - 12:05 pm Alon Korngreen (Bar-Ilan Univ.)
"Experimentally guided modeling of dendritic calcium spikes in the apical dendrite of L5 pyramidal neurons"
12:05 pm - 12:10 pm Discussion
12:10 pm - 12:25 pm Dan Nicholson (Rush Univ. Med. Center)
"An age-related, progressive, and reversible HCN channelopathy in two mouse models of Alzheimer's disease"
12:25 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session I
5:30 pm - 7:30 pmDendritic spines as sites of plasticity and integration
Discussion Leader: Erin Schuman (Max Planck Inst. Frankfurt)
5:30 pm - 6:00 pm Ryohei Yasuda (Max Planck Inst. Florida)
"Imaging signal transduction in single dendritic spines"
6:00 pm - 6:10 pm Discussion
6:10 pm - 6:40 pm Rich Mooney (Duke Univ.)
"Song learning: from synapse to behavior"
6:40 pm - 6:50 pm Discussion
6:50 pm - 7:20 pm Judit Makara (Hungarian Academy of Science)
"Shaping of dendritic integration by K+ channels in CA3 pyramidal neurons"
7:20 pm - 7:30 pm Discussion
8:00 pmDinner
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmDendritic integration of inhibition
Discussion Leader: Holly Cline (Scripps Inst.)
9:00 am - 9:30 am Idan Segev (Hebrew Univ.)
"A new view on dendritic inhibition"
9:30 am - 9:40 am Discussion
9:40 am - 10:10 am Angus Silver (Univ. College London)
"Effect of in vivo-like background synaptic input on synaptic integration in L5 pyramidal cells"
10:10 am - 10:20 am Discussion
10:20 am Coffee Break
10:50 am - 11:20 am Matthew Larkum (Univ. Berlin)
"NMDA spikes in vivo"
11:20 am - 11:30 am Discussion
11:30 am - 12:00 pm Elly Nedivi (Massachusetts Inst. Technology)
"Structural dynamics of neocortical inhibitory circuits"
12:00 pm - 12:10 pm Discussion
12:10 pm - 12:25 pm Thomas Younts (Albert Einstein)
"CA1 pyramidal cell theta-burst firing triggers endocannabinoid-mediated long-term depression at both somatic and dendritic inhibitory synapses"
12:25 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session II
5:30 pm - 7:30 pmSignaling from nucleus to dendrites and back
Discussion Leader: Mike Ehlers (Pfizer)
5:30 pm - 6:00 pm Wolfgang Enard (Ludwig Maximilians Univ./ Max Planck Inst. Leipzig)
"Dendrite morphology and the evolution of speech"
6:00 pm - 6:10 pm Discussion
6:10 pm - 6:40 pm Hilmar Bading (Univ. Heidelberg)
"Regulation of neuronal structure by nuclear calcium signaling"
6:40 pm - 6:50 pm Discussion
6:50 pm - 7:20 pm Eric Huang (Univ. California San Francisco)
"RNA Binding Protein FUS and Dendrite Development: Implications in Neurodegenerative Diseases"
7:20 pm - 7:30 pm Discussion
7:30 pm - 8:00 pmBusiness Meeting
Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair
8:00 pmDinner
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmDendritic control of sensory processing
Discussion Leader: Dan Johnston (Univ. Texas Austin)
9:00 am - 9:30 am Florian Engert (Harvard Univ.)
"Visual processing in larval zebrafish"
9:30 am - 9:40 am Discussion
9:40 am - 10:10 am Randy Bruno (Columbia Univ.)
"Dendritic organization of thalamocortical synapses in the cortical input layers"
10:10 am - 10:20 am Discussion
10:20 am Coffee Break
10:50 am - 11:20 am Tomomi Shimogori (Riken Brain Sci Inst.)
"BTB/POZ domain containing Btbd3 mediates activity-dependent dendritic field patterning in the developing cerebral cortex"
11:20 am - 11:30 am Discussion
11:30 am - 11:45 am Lucy Palmer (University of Bern)
"The influence of NMDA spikes on action potential generation during sensory input"
11:45 am - 11:50 am Discussion
11:50 am - 12:05 pm Chay Kuo (Duke)
"Cysteine proteinase-1 controls context-dependent elaboration of two distinct dendritic trees from the same neuron"
12:05 pm - 12:10 pm Discussion
12:10 pm - 12:25 pm Simon Chen (UCSD)
"The Transcription Factor MEF2 is a Master Regulator of Visual Experience-Driven Functional and Structural Metaplasticity in the Developing Brain"
12:25 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session II
5:30 pm - 7:30 pmLearning, memory and dendritic plasticity
Discussion Leader: Greg Stuart (Australian National Univ.)
5:30 pm - 6:00 pm Yi Zuo (Univ. California Santa Cruz)
"Spatiotemporal changes of cortical synapses in formation of motor memory"
6:00 pm - 6:10 pm Discussion
6:10 pm - 6:40 pm Thomas Nevian (Univ. Bern)
"Neuropathic pain causes pathological changes of dendritic properties in pyramidal neurons of the anterior cingulate cortex"
6:40 pm - 6:50 pm Discussion
6:50 pm - 7:20 pm Attila Losonczy (Columbia Univ.)
"Dendritic inhibitory circuits supporting hippocampal episodic memory"
7:20 pm - 7:30 pm Discussion
8:00 pmDinner
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDeparture
Research reported in this publication was supported by the National Institute Of Neurological Disorders And Stroke of the National Institutes of Health under Award Number R13NS083184. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
Last Updated: May 15, 2013
 
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