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Germinal Stem Cell Biology
July 14-19, 2013
The Chinese University of Hong Kong
Hong Kong, China
Chair:
Wai-Yee Chan

Vice Chair:
Yun-Fai Chris Lau
Application Deadline
Applications for this meeting must be submitted by June 16, 2013. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

The germline is unique in mammals as it is the only cell lineage that undergoes mitosis, meiosis, and differentiation. The lineage is comprised of an array of developmentally distinct stages from the germinal stem cell to the terminally differentiated sperm or oocyte. Elucidation of the biology of germline development as well as germinal stem cell maintenance or differentiation would be of great impact to both the biomedical as well as agricultural communities. For example, improvements in assisted reproduction (in humans) and cloning (in animals) technologies are dependent on advancing current in vitro systems towards more efficient oocyte development. Similarly, the development of methodologies to maintain germinal stem cell systems for male or female instances of spontaneous or drug/toxin-induced infertility in humans or, in the case of agricultural animals, for alternative modes of cryopreservation to maintain germplasm or to improve transgenic technologies for the enhancement of production traits and the generation of animal models with nutraceutical worth, are all important.

Contributors
SUNDAY
4:00 pm - 8:00 pmArrival and Check-in (Office Closed 6:00 pm - 7:45 pm)
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff and Chair Wai-Yee Chan (CUHK, China)
7:40 pm - 9:30 pmSex Determination, and Germ Cell Differentiation
Discussion Leader: Peter Koopman (University of Queensland, Australia)
7:40 pm - 8:05 pmBlanche Capel (Duke University, USA)
"Sex Determination - Testis and Ovary Development"
8:05 pm - 8:15 pmDiscussion
8:15 pm - 8:40 pmJosephine Bowles (University of Queensland, Australia)
"Sex Determination in Mammalian Germ Cells"
8:40 pm - 8:50 pmDiscussion
8:50 pm - 9:15 pmMartin Matzuk (Baylor College of Medicine, USA)
"Small molecule inhibitor of spermatogenesis"
9:15 pm - 9:30 pmDiscussion
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmFemale Germinal Stem Cells
9:00 am - 9:10 amDiscussion Leader: David F. Albertini (University of Kansas, USA)
9:10 am - 9:35 amJi Wu (Shanghai Jiao Tong University, China)
"Production of offspring from a germline stem cell line derived from neonatal ovaries"
9:35 am - 9:45 amDiscussion
9:45 am - 10:10 amEvelyn E. Telfer (University of Edinburgh, UK)
"Grow eggs to maturity in vitro"
10:10 am - 10:20 amDiscussion
10:20 am - 10:50 am Group Photo / Coffee Break
10:50 am - 11:15 amCarlos Simon (University of Valencia, Spain)
"Ovarian stem cells"
11:15 am - 11:25 amDiscussion
11:25 am - 11:50 amKehkooi Kee (Tsinghua University, China)
"Human female germ cell biology"
11:50 am - 12:00 pmDiscussion
12:00 pm - 12:10 pmTBA (speakers to be selected from submitted abstracts)
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:25 pmTBA (speakers to be selected from submitted abstracts)
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmMale Germinal Stem Cells
7:30 pm - 7:40 pmDiscussion Leader: Robin Lovell-Badge (MRC, UK)
7:40 pm - 8:05 pmMarie Claude Hofmann (MD Anderson Cancer Center, USA)
"Spermatogonial stem cell model"
8:05 pm - 8:15 pmDiscussion
8:15 pm - 8:40 pmKyle E. Orwig (University of Pittsburgh, USA)
"Preserving fertility with spermatogonial stem cells"
8:40 pm - 8:50 pmDiscussion
8:50 pm - 9:15 pmZuping He (Shanghai Jiao Tong University, China)
"Gene regulation and signaling pathways in the regulation of spermatogonial stem cells"
9:15 pm - 9:30 pmDiscussion
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmEpigenetic Programming
9:00 am - 9:10 amDiscussion Leader: Pei Duanqing (Guangzhou Institute of Biomedicine and Health, China)
9:10 am - 9:35 amMyriam Hemberger (Babraham Institute, UK)
"Genetic and epigenetic control of early cell lineage decisions"
9:35 am - 9:45 amDiscussion
9:45 am - 10:10 amYi Zhang (Harvard Medical School, USA)
"Epigenetic regulation in stem cell reprogramming - Hydroxymethylation"
10:10 am - 10:20 amDiscussion
10:20 am - 10:50 am Coffee Break
10:50 am - 11:15 amHiroyuki Sasaki (National Institute of Genetics, Japan)
"Epigenetic events in mammalian germ-cell development"
11:15 am - 11:25 amDiscussion
11:25 am - 11:50 amSatoshi Namekawa (University of Cincinnati, USA)
"Epigenetic dynamics of the sex chromosomes in the male germline"
11:50 am - 12:00 pmDiscussion
12:00 pm - 12:10 pmTBA (speakers to be selected from submitted abstracts)
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:25 pmTBA (speakers to be selected from submitted abstracts)
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmGermline Stem Cells - Transdifferentiation
7:30 pm - 7:40 pmDiscussion Leader: Paul S. Cooke (University of Florida, USA)
7:40 pm - 8:05 pmPaul S. Cooke (University of Florida, USA)
"Plasticity of spermatogonial stem cells"
8:05 pm - 8:15 pmDiscussion
8:15 pm - 8:40 pmPierre Fouchet (INSERM, France)
"Spermatogonia to germinal stem cell transdifferentiation"
8:40 pm - 8:50 pmDiscussion
8:50 pm - 9:15 pmYosef Buganim (Whitehead Institute, MIT, USA)
"Reprogramming of fibroblasts to embryonic Sertoli-like cells"
9:15 pm - 9:30 pmDiscussion
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmGerm Cell Development
9:00 am - 9:10 amDiscussion Leader: Haifan Lin (Yale University, USA)
9:10 am - 9:35 amTeruhiko Wakayama (RIKEN, Japan)
"Genomic reprogramming in mouse oocyte"
9:35 am - 9:45 amDiscussion
9:45 am - 10:10 amPaolo Sassone-Corsi (University of California, Irvine, USA)
"Molecular control of circadian rhythms and differentiation of male germ cells"
10:10 am - 10:20 amDiscussion
10:20 am - 10:50 am Coffee Break
10:50 am - 11:15 amTin Lap Lee (The Chinese University of Hong Kong, China)
"Long non-coding RNA in spermatogonial stem cell development"
11:15 am - 11:25 amDiscussion
11:25 am - 11:50 amMartine Culty (McGill University, Canada)
"Gonocyte differentiation"
11:50 am - 12:00 pmDiscussion
12:00 pm - 12:10 pmTBA (speakers to be selected from submitted abstracts)
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:25 pmTBA (speakers to be selected from submitted abstracts)
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair
7:30 pm - 9:30 pmClinical Aspects - Diagnosis and Therapeutic Strategies for Germ Cell Diseases
7:30 pm - 7:40 pmDiscussion Leader: Csilla Krausz (University of Florence, Italy)
7:40 pm - 8:05 pmDouglas Carrell (University of Utah, USA)
"Genetic Diagnostics in male infertility: from research to clinic"
8:05 pm - 8:15 pmDiscussion
8:15 pm - 8:40 pmZijiang Chen (Shandong University, China)
"Premature Ovarian Failure"
8:40 pm - 8:50 pmDiscussion
8:50 pm - 9:15 pmFrank Tuttelmann (University of Munster, Germany)
"Pharmacogenetics and personalized hormonal therapy: an update"
9:15 pm - 9:30 pmDiscussion
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmGerm Cell Tumors
9:00 am - 9:10 amDiscussion Leader: Peter Vogt (University of Heidelberg, Germany)
9:10 am - 9:35 amEwa Rajpert-De Meyst (University of Copenhagen, Denmark)
"Genotype and phenotype of carcinoma-in-situ cells"
9:35 am - 9:45 amDiscussion
9:45 am - 10:10 amLeendert Looijenga (Erasmus Medical Center, Netherlands)
"Pathogenesis of testicular germ cell tumors; possible role of the Y chromosome"
10:10 am - 10:20 amDiscussion
10:20 am - 10:50 am Coffee Break
10:50 am - 11:15 amRaju Chaganti (Memorial Sloan-Kettering Cancer Center, USA)
"microRNA metabolism in malignant germ cells and of epigenetic aspects"
11:15 am - 11:25 amDiscussion
11:25 am - 11:50 amHubert Schorle (Bonn Medical School, Germany)
"Cellular plasticity during the development of germ cell tumors - the role of the tumor microenvironment on the fate of CIS"
11:50 am - 12:00 pmDiscussion
12:00 pm - 12:10 pmTBA (Selected from submitted abstracts)
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:25 pmTBA (Selected from submitted abstracts)
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmApplication of Stem Cells in Animal Technology
4:00 pm - 4:10 pmDiscussion Leader: Le Ann Blomberg (USDA, USA)
4:10 pm - 4:35 pmRamiro Alberio (University of Nottingham, UK)
"Developmental mechanisms involved in the generation of pluripotent cells"
4:35 pm - 4:45 pmDiscussion
4:45 pm - 5:10 pmFanyi Zeng (Shanghai Jiao Tong University, China)
"Studying Stem Cell Biology Using In Utero Transplantation in Animal Models"
5:10 pm - 5:20 pmDiscussion
5:20 pm - 5:45 pmTBA
5:45 pm - 6:00 pmDiscussion
6:00 pmDinner
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDeparture
Last Updated: May 16, 2013
 
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