The Gordon Research Seminar on Molecular Pharmacology is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.
Young scientists and senior investigators (discussion leaders) who are at the forefront of their field will discuss 3 main aspects of GPCRs biology: i) Structural biology, ii) Cell signalling and trafficking, iii) Physiological and pathological process.
|1:30 pm - 4:30 pm||Arrival and Check-in|
|3:00 pm - 3:15 pm||Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair|
|3:15 pm - 4:00 pm||Keynote Lecture|
|Discussion Leaders: Jean Philippe Pin (IGF, CNRS-INSERM, France) and Elena Monica Borroni (Humanitas Clinical and Research, Italy)|
|3:15 pm - 3:45 pm||Michel Bouvier (Institut de Recherche en Immunologie et Cancérologie, Canada)
"Folding and Traficking of GPCR; Targets for Drug Discovery?"
|3:45 pm - 4:00 pm||Discussion|
|4:00 pm - 5:30 pm||Poster Session I|
|5:30 pm - 7:30 pm||From the Structure to GPCRs Function|
|Discussion Leaders: Ron Dror (D.E. Shaw Research, New York, NY USA) and Robert Lane (Monash Institute Of Pharmaceutical Sciences, Australia)|
|5:30 pm - 5:50 pm||Daniel Wacker (The Scripps Research Institute)
"Structural Basis of Hallucinogen Signaling through Serotonin and Opioid Receptors"
|5:50 pm - 6:00 pm||Discussion|
|6:00 pm - 6:20 pm||A.J. Venkatakrishnan (MRC Laboratory of Molecular Biology)
"Molecular signatures of G protein-coupled receptors"
|6:20 pm - 6:30 pm||Discussion|
|6:30 pm - 6:50 pm||Martin Ostermaier (Paul Scherrer Institute)
"Arrestin rhodopsin binding at single amino acid resolution"
|6:50 pm - 7:00 pm||Discussion|
|7:00 pm - 7:20 pm||Miriam Peeters (Leiden Academic Centre for Drug Research)
"A general, tethered inverse agonist model for adhesion 7TM receptor activation - based on selective expression in enteroendocrine cells"
|7:20 pm - 7:30 pm||Discussion|
|7:30 am - 8:30 am||Breakfast|
|9:00 am - 10:30 am||GPCRs in cell communication|
|Discussion Leaders: Martin Lhose (University of Wuerzburg, Germany) and Nicola Smith (Victor Chang Cardiac Research Institute, Australia)|
|9:00 am - 9:20 am||Abla Benleulmi (INSERM U1016)
"Identification of new melatonin receptor functions by protein interactome mining"
|9:20 am - 9:30 am||Discussion|
|9:30 am - 9:50 am||Sean Peterson (Duke University)
"The physiological and evolutionary significance of dopamine 2 receptor functional selectivity"
|9:50 am - 10:00 am||Discussion|
|10:00 am - 10:20 am||Aaron Overland (University of California, San Diego)
"GPCRs and Heterotrimeric G Proteins Directly Regulate Membrane Type-1 Matrix Metalloprotease"
|10:20 am - 10:30 am||Discussion|
|10:30 am - 11:00 am||GPCRs in vivo: Physiology and Diseases|
|Discussion Leaders: Brigitte Kieffer (IGBMC, Strasbourg, France) and Aaron Snead (University of California, USA)|
|10:30 am - 10:50 am||Amantha Thathiah (Catholic University of Leuven)
"Beta-arrestin 2 regulates GPCR function in Alzheimer's disease"
|10:50 am - 11:00 am||Discussion|
|11:00 am - 12:30 pm||Poster Session II|
|Coffee will be served in the poster area from 11:00 am - 11:30 am|
|1:30 pm - 2:30 pm||GPCRs in vivo: Physiology and Diseases (continued)|
|Discussion Leader: Brigitte Kieffer (IGBMC, Strasbourg, France)|
|1:30 pm - 1:50 pm||Camilla West (Imperial College London)
"Regulation of LH/CG receptor signaling in human endometrium and perturbations in recurrent pregnancy loss"
|1:50 pm - 2:00 pm||Discussion|
|2:00 pm - 2:20 pm||Stephanie Dusaban (University of California, San Diego)
"Phospholipase C-epsilon links G-protein coupled receptor activation to inflammatory responses in astrocytes and in models of CNS injury and disease"
|2:20 pm - 2:30 pm||Discussion|
|2:30 pm - 3:00 pm||Evaluation Period|
|Fill out GRS Evaluation Forms|
|3:00 pm||Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm.|
Funding for this conference was made possible (in part) by 1 R13 DA035525-01 from the National Institute on Drug Abuse. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
Last Updated: April 18, 2013