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RNA Editing (GRS)
Gordon Research Seminar

RNA and DNA Editing and Modification

Dates

January 5-6, 2013

Location

Hotel Galvez
Galveston, TX

Organizers

Chair:
Yiannis A. Savva

Associate Chair:
Claire E. Hamilton

Meeting Description

The Gordon Research Seminar on RNA Editing is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The focus of this meeting will be on the structural insights, target site recognition, catalysis, regulation, and functional interactions of diverse nucleic acid editing and modification mechanisms, as well as on the evolution, diversity, biological roles, and medical impacts of editing and modification.

Related Meeting

This GRS was held in conjunction with the "RNA Editing" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.

Contributors

Meeting Program

SATURDAY
2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session
Discussion Leader: Dewi Harjanto (Rockefeller University)
3:45 pm - 4:15 pmKeynote Speaker: Kazuko Nishikura (The Wistar Institute)
"RNA editor acts as RNA silencer"
4:15 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session I
6:00 pmDinner
7:30 pm - 9:30 pmBiological Roles of Editing and Modification
Discussion Leader: Isabel Vallecillo-Viejo (University Of Puerto Rico) and Rui Zhang (Stanford University)
7:30 pm - 7:50 pmYlva Ekdahl (Stockholm University)
"Editing of miRNAs may affect dendritic outgrowth during development by fine-tuning Pumilio 2 protein levels"
7:50 pm - 8:00 pmDiscussion
8:00 pm - 8:20 pmMeng How Tan (Stanford University)
"A Quantitative Atlas of RNA Editing Sites in Mammals"
8:20 pm - 8:30 pmDiscussion
8:30 pm - 8:50 pmMikaela Behm (Stockholm University)
"Regulation of A-to-I RNA editing during brain development and neuronal activation"
8:50 pm - 9:00 pmDiscussion
9:00 pm - 9:20 pmXiao Wang (The University Of Chicago)
"N6-methyladenosine-specific RNA-binding proteins in mRNA regulation"
9:20 pm - 9:30 pmDiscussion
SUNDAY
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amStructure, function and specificity of editing/modification systems
Discussion Leader: Dan Dominissini (Tel-Aviv University) and Bhalchandra Rao (Ohio State University)
9:00 am - 9:20 amEric Fritz (Rockefeller University)
"Genome-wide analyses demonstrate that AID is neither demethylates DNA nor edits RNA in activated B cells"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amWilliam Swinehart (Ohio State University)
"Inefficient substrate recognition of a multi-functional tRNA modification enzyme"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amMichael Guy (University Of Rochester)
"Conserved circuitry in eukaryotes for crucial Trm7 modifications of the tRNA anticodon loop"
10:20 am - 10:30 amDiscussion
10:30 am - 10:50 amYicheng Long (Ohio State University)
"Multiple functions of a family of 3'-to-5' polymerases in Dictyostelium discoideum"
10:50 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session II
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmBioinformatic and Evolutionary Analysis of Editing and Modification
Discussion Leader: Cai Chen (The Ohio State University) and Takuma Suematsu (University Of California, Irvine)
1:30 pm - 1:50 pmGokul Ramaswami (Stanford University)
"Identifying RNA Editing Sites Using RNA Sequencing Data Alone"
1:50 pm - 2:00 pmDiscussion
2:00 pm - 2:20 pmCintia Hongay (Clarkson University)
"The role of IME4 in metazoan development"
2:20 pm - 2:30 pmDiscussion
2:30 pm - 3:00 pmEvaluation Period
Fill out GRS Evaluation Forms
3:00 pmGordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm.
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