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Microfluidics, Physics & Chemistry of
Gordon Research Conference

Challenges, Advances and New Technologies for Diagnostics

Dates

June 9-14, 2013

Location

Renaissance Tuscany Il Ciocco
Lucca (Barga), Italy

Organizers

Chairs:
James P. Landers & Paul Yager

Vice Chairs:
Shelley L. Anna & Jonathan D. Posner

Meeting Description

The Gordon Research Conference (GRC) on the Physics and Chemistry of Microfluidics continues to present the latest developments on both the fundamental aspects of fluid flow in micro- and nanoscale systems, as well as the application of microfluidic analytical systems to solving real-world problems. With a novel focus on paper microfluidics and clinical diagnostics (both bench-to-bedside and global health), discussions will include platform technologies for global health, novel approaches to passive flow control, challenges in commercialization of microfluidic systems for real-world applications, analytical systems driven by centrifugal force, microscale acoustic cell sorting and next generation sequencing. As microfluidics continues to expand in fundamental understanding and application to more complicated systems, this conference brings together the thought leaders in unique subfields of microfluidic development that will ultimately form the components and substrates of next-generation systems. Amidst the beauty of Tuscany, in-depth discussions probe the veracity of unpublished data presented by leading scientists and engineers pushing the envelope of development in microfluidic systems that advance biology, biomedical science and clinical diagnostics. With participants spanning the spectrum from academia to government and industry, a unique flavor evolves from the interaction of participants with dissimilar backgrounds, but focused on the common goal of facilitating a continued maturation of microfluidic technologies for application in the real world.

Related Meeting

This GRC was held in conjunction with the "Microfluidics, Physics & Chemistry of" Gordon Research Seminar (GRS). Refer to the associated GRS program page for more information.

Contributors

Meeting Program

SUNDAY
4:00 pm - 8:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmFluidic Control
Discussion Leader: Dino DiCarlo (University of California-Los Angeles)
7:40 pm - 8:20 pmStephen Quake (Stanford)
"Microfluidics: Beyond Biology"
8:20 pm - 8:35 pmDiscussion
8:35 pm - 9:15 pmMatthew Begley (University of California - Santa Barbara)
"Frequency-based Flow Control in Microfluidics using Passive Deformable Features"
9:15 pm - 9:30 pmDiscussion
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmPaper Microfluidics
Discussion Leader: Sabeth Verpoorte (Groningen University)
9:00 am - 9:35 amBarry Lutz (University of Washington)
"A Tour of Physical Principles in Paper Microfluidics: The Ancient, The Old, and The New"
9:35 am - 9:55 amDiscussion
9:55 amGroup Photo / Coffee Break
10:25 am - 11:00 amDavid Moore (GE Global Research)
"Towards Precision Paper-based Fluidics: Advanced Diagnostic Components & Reagents"
11:00 am - 11:20 amDiscussion
11:20 am - 11:55 amChuck Henry (Colorado State University)
"Assessing Exposure to Environmental Pollutants Using Paper-Based Analytical Devices"
11:55 am - 12:15 pmDiscussion
12:15 pm - 12:30 pmSnapshots: Paper Microfluidics
  • Debjani Paul (Indian Institute of Technology Bombay)
    "Thread and Paper-based Devices for Sensing and Diagnostic Applications"
  • Emilia Nery (UNICAMP, Brazil)
    "Development of a Paper Based Analytical Device for Simultaneous Detection of Cholesterol, Glucose and Uric Acid"
  • David Wood (University of Minnesota)
    "Detection of Synthetic Urinary Biomarkers using a Lateral Flow Assay"
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session
5:30 pm - 7:30 pmPaper Microfluidics
Discussion Leader: Marya Lieberman (University of Notre Dame)
5:30 pm - 6:05 pmCharles Mace (Diagnostics for All)
"A Patterned-paper Device for Measurement of Immunity Status"
6:05 pm - 6:25 pmDiscussion
6:25 pm - 7:00 pmDavid Juncker (McGill University)
"Microfluidics on Threads"
7:00 pm - 7:20 pmDiscussion
7:20 pm - 7:30 pmSnapshots: Bead-based Microfluidics
  • Polly Fordyce (University of California San Francisco)
    "A Microfluidic Platform for Programmable Peptide Synthesis"
  • Stéphanie Descroix (Institut Curie, France)
    "A Microfluidic Fluidized Bed for Bioanalytical Applications"
8:00 pmDinner
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmMicrofluidic Acoustics
Discussion Leader: Joel Voldman (Massachusetts Institute of Technology)
9:00 am - 9:35 amHenrik Bruus (Technical University of Denmark)
"Theory of Streaming and Radiation Forces in Microchannel Acoustophoresis"
9:35 am - 9:55 amDiscussion
9:55 amCoffee Break
10:25 am - 11:00 amSteven Graves (University of New Mexico)
"Microfluidic Acoustic Flow Cytometry: A Pathway to Point-of-Care and High-Speed Parallel Cellular Diagnostics"
11:00 am - 11:20 amDiscussion
11:20 am - 11:55 amThomas Laurell (Lund University)
"Challenges and Opportunities for Acoustophoresis in Clinical Applications"
11:55 am - 12:15 pmDiscussion
12:15 pm - 12:30 pmSnapshots: Rare and Single Cells
  • Justin Besant (University of Toronto)
    "A Velocity Valley Chip for Rapid Capture of Nanoparticle-Bound Circulating Tumor Cells"
  • Rohit Karnik (Massachusetts Institute of Technology)
    "High-throughput Capture and Release of Cells Using Multivalent DNA Networks in a Microfluidic Device"
  • Venkat Chokkalingam (Radboud University, Netherlands)
    "Single Cell Analysis of Cytokine Production"
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session
5:30 pm - 7:30 pmCentrifugally-driven Microfluidics
Discussion Leader: Roland Zengerle (University of Freiburg)
5:30 pm - 6:05 pmYoon-Kyoung Cho (Ulsan National Institute of Science and Technology)
"Centrifugal Microfluidics"
6:05 pm - 6:25 pmDiscussion
6:25 pm - 7:00 pmMarc Madou (University of California - Irvine)
"Electrochemistry on a Rotating Fluidic Platform"
7:00 pm - 7:20 pmDiscussion
7:20 pm - 7:30 pmSnapshots: Centrifugally-driven Microfluidics
  • Sune Andreasen (Technical University of Denmark)
    "Real-time Electrochemical Detection on a Spinning Disc"
  • Anna Line Brogger (Technical University of Denmark)
    "High-throughput Label-free Recognition of Prognostic Biomarker suPAR"
8:00 pmDinner
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmDiagnostics
Discussion Leader: Amy Herr (University of California - Berkeley)
9:00 am - 9:35 amRosanna Peeling (London School of Hygiene & Tropical Medicine)
"Diagnostics to Improve Global Health: Unmet Needs and Opportunities"
9:35 am - 9:55 amDiscussion
9:55 amCoffee Break
10:25 am - 11:00 amBernhard Weigl (PATH)
"Low-cost, Instrument Free Microfluidic Diagnostics for Global Health"
11:00 am - 11:20 amDiscussion
11:20 am - 11:55 amSam Sia (Columbia University)
"Toward Making Real-World Impact with Point-of-Care Diagnostics"
11:55 am - 12:15 pmDiscussion
12:15 pm - 12:30 pmSnapshots: Diagnostics
  • Winnie Svendsen (DTU Nanotech)
    "Sample Handling Issues in Microfluidic Diagnostics"
  • Ashleigh Theberge (University of Wisconsin - Madison)
    "Enabling Companion Diagnostic Platforms for Cancer Treatment"
  • Toshihiro Kamei (AIST, Japan)
    "Towards a Fully Integrated Fluorescence Detector for Point-of-Care Microfluidic Diagnostics"
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session
5:30 pm - 7:30 pmDiagnostics
Discussion Leader: Abe Lee (University of California - Irvine)
5:30 pm - 6:05 pmCarl Meinhart (University of California - Santa Barbara)
"Free-Surface Microfluidics and SERS for High Perfomance Sample Capture and Analysis"
6:05 pm - 6:25 pmDiscussion
6:25 pm - 7:00 pmDavid Erickson (Cornell University)
"Smartphone-based Molecular Diagnostics"
7:00 pm - 7:20 pmDiscussion
7:20 pm - 7:30 pmSnapshots: Bead-based Microfluidics
  • Sindy Tang (Stanford University)
    "Droplet Microfluidics for Diagnostics Applications"
  • Myriam Cubizolles (CEA-LETI, France)
    "Development of a Point-of-Care System to Follow Up Patients under Oral Anticoagulant Therapies"
7:30 pm - 8:00 pmBusiness Meeting
Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair
8:00 pmDinner
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmCommercialization of Microfluidic Technology
Discussion Leader: Jean-Louis Viovy (Curie Institute)
9:00 am - 9:35 amJoan Bienvenue (University of Virginia)
"Commercialization of Integrated DNA Analysis Systems for Forensic and Biometric Application"
9:35 am - 9:55 amDiscussion
9:55 amCoffee Break
10:25 am - 11:00 amJason Hayes (miniFAB)
"5 Tips for Commercialization of Lab-on-a-Chip"
11:00 am - 11:20 amDiscussion
11:20 am - 11:55 amAlbert van den Berg (University of Twente)
"From Lab-on-a-Chip Research to Commercial Application"
11:55 am - 12:15 pmDiscussion
12:15 pm - 12:30 pmSnapshots: Commercialization
  • Anne Le Nel (Fluigent, France)
    "Pressure Actuation & Flow-rate Control, Merging the Best of 2 Worlds"
  • Sally Anderson (Sharp Laboratories of Europe, UK)
    "Microfluidics on CG-Silicon - Commercialisation Opportunities"
  • William M. Behnke-Parks (Wave 80 Biosciences)
    "Next-generation Diagnostics for Global Health"
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session
5:30 pm - 7:30 pmNext Generation Sequencing
Discussion Leader: Jan Eijkel (University of Twente)
5:30 pm - 6:10 pmMichael Ramsey (University of North Carolina - Chapel Hill)
"Manipulation and Characterization of Single DNA Molecules using Nanofluidic Structures"
6:10 pm - 6:30 pmDiscussion
6:30 pm - 7:10 pmJuan Hernandez-Ortiz (Universidad Nacional de Colombia)
"Genomic-DNA manipulation through Nano-confinement, Electrostatics and Hydrodynamics towards Cost-effective and High-throughput Devices"
7:10 pm - 7:30 pmDiscussion
8:00 pmDinner
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDeparture

Funding for this conference was made possible (in part) by R13EB016992-01 from the National Institute of Biomedical Imaging and Bioengineering. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
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