Gordon Research Conferences
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Conference Program
 
Environmental Endocrine Disruptors
An Integrated Perspective from Wildlife to Human Health
May 11-16, 2014
Renaissance Tuscany Il Ciocco Resort
Lucca (Barga), Italy

Related Meeting Information
The Environmental Endocrine Disruptors Gordon Research Conference was held in conjunction with the Environmental Endocrine Disruptors Gordon Research Seminar. Please refer to the Environmental Endocrine Disruptors GRS web page for more information.

The 2014 Gordon Research Conference on Environmental Endocrine Disruptors will take place May 11-16 in the beautiful resort of Ciocco in Tuscany, Italy. The conference will highlight recent advances in the field and focus on work that might shape the next decade of research, against the 2013-2014 backdrop of numerous authoritative reviews of the science and the knowledge gaps that hamper progress to better protect the public and wildlife. We will feature a range of topics that address these knowledge gaps, including new insights into endocrine systems from invertebrates to humans, new information on exposures with a focus on mixtures and exposure routes, mechanisms of endocrine function and dysfunction, wildlife human connections and the importance of critical windows of exposure. Imperatively, there will also be contributions about new innovations in chemical and biological screening for endocrine disruption. The Conference will bring together internationally renowned scientists who are at the forefront of their field. The Conference will also provide opportunities for junior scientists and graduate students to present their work in poster format and exchange ideas with leaders in the field. Some poster presenters will be selected for short talks. The collegial atmosphere that has traditionally characterized the GRC on Environmental Endocrine Disruptors will provide the perfect setting for intellectual development and collegial discussions in the afternoons and evenings to further research in this field. This year, a Gordon Research Seminar (GRS) will be held the day prior to the GRC, and we encourage applicants at the trainee level to apply to both meetings. The 2014 GRC will be a unique forum for learning about interdisciplinary, cutting-edge research in this area of growing importance.


Contributors

SUNDAY
4:00 pm - 8:00 pmArrival and Check-in (Check-in Desk Closed 6:00 pm - 7:45 pm)
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmKeynote Session: EDCs: What Does the Future Hold?
Discussion Leader: TBA
7:40 pm - 8:20 pmScott Gilbert (Swarthmore University and U. Helsinki)
"The New Normal: Developing in the Technoestrogenic Niche"
8:20 pm - 8:35 pmDiscussion
8:35 pm - 9:15 pmJohn Warner (Warner Babcock Institute for Green Chemistry)
"Green Chemistry Approaches to Endocrine Disruptor Free Products"
9:15 pm - 9:30 pmDiscussion
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmEndocrine Disrupting Chemicals and Female Reproductive Health
9:00 am - 9:05 amDiscussion Leader: John McLachlan (Tulane University)
"Introduction"
9:05 am - 9:35 amSue Fenton (NIEHS)
"Lifelong Impact on the Female Reproductive System in Mice Prenatally Exposed to Perfluorooctanoic Acid"
9:35 am - 9:45 amDiscussion
9:45 am - 10:05 amJessica LaRocca (Harvard University)
"Prenatal Endocrine Female Reproduction Disrupting Chemical Exposure Is Associated with Epigenetic Alterations in the Placenta"
10:05 am - 10:15 amDiscussion
10:15 amCoffee Break
10:30 am - 11:00 amAndreas Kortenkamp (Brunel University, London)
"Exposures to Xenoestrogens - Assessing the Magnitude of the Problem from a Mixture Perspective"
11:00 am - 11:10 amDiscussion
11:10 am - 11:40 amJohn Sumpter (Brunel University, London)
"The Exquisite Sensitivity of Fish Reproduction to Steroid Hormones in the Aquatic Environment Both Singularly and in Combination"
11:40 am - 11:50 amDiscussion
11:50 am - 12:20 pmCheryl Murphy (Michigan State University)
"Linking Upstream Neuroendocrine Disruption to the Hypothalamus-Pituitary-Gonadal Axis to Predict Adverse Effects on Fecundity Across Fish, Birds and Mammals"
12:20 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:30 pmFree Time
4:30 pm - 6:00 pmPoster Session
6:00 pm - 8:00 pmEDCs and Cancer
6:00 pm - 6:10 pmDiscussion Leader: Les Reinlib (NIEHS)
"Introduction"
6:10 pm - 6:40 pmAna Soto (Tufts University)
"Fetal Exposure to BPA and Adult Mammary Cancer"
6:40 pm - 6:50 pmDiscussion
6:50 pm - 7:20 pmSusan Teitelbaum (Mt. Sinai School of Medicine, NY)
"Exposures to EDC Mixtures During Critical Developmental Windows and Breast Cancer Outcomes"
7:20 pm - 7:30 pmDiscussion
7:30 pm - 7:50 pmJerome Hershman (UCLA School of Medicine)
"Environmental Toxins Cause Double Strand DNA Breaks in Thyroid Cells that Could Lead to Oncogenic Mutations Resulting in Thyroid Cancer"
7:50 pm - 8:00 pmDiscussion
8:00 pmDinner
TUESDAY
7:30 am - 8:30 amBreakfast
8:30 amGroup Photo
9:00 am - 12:30 pmMale Reproductive Health
9:00 am - 9:05 amDiscussion Leader: Andreas Kortenkamp (Brunel University)
"Introduction"
9:05 am - 9:35 amAlex Burdorf (Erasmus University, NL)
"Associations of Maternal Exposure to Mixtures of EDC with Cryptorchidism and Hypospadias in Offspring"
9:35 am - 9:45 amDiscussion
9:45 am - 10:05 amKarma Fussell (BASF SE)
"Testing Mixtures of Endocrine Disruptors In Vivo at Human-Relevant Exposure Levels"
10:05 am - 10:15 amDiscussion
10:15 amCoffee Break
10:30 am - 11:00 amDavid Møbjerg Kristensen (University of Copenhagen)
"Towards an Understanding of the Endocrine Disturbance by Mild Analgesics"
11:00 am - 11:10 amDiscussion
11:10 am - 11:40 amDonald Tillett (USGS)
"Mechanisms of Feminisation in Fish"
11:40 am - 11:50 amDiscussion
11:50 am - 12:20 pmElizabeth Hill (University of Sussex, UK)
"Effect-Directed Analyses with Human and Fish Tissue Material Reveals Totally New Chemical Exposures"
12:20 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:30 pmFree Time
4:30 pm - 6:00 pmPoster Session
6:00 pm - 8:00 pmDiscourse on the Value of Model Systems to Predict EDC Effects on the Perinatal Human
6:00 pm - 6:10 pmDiscussion Leader: Bruce Blumberg (U. C. Irvine, USA)
"Introduction"
6:10 pm - 6:40 pmBernard Jegou (INSERM, France)
"The Importance of Animal Models to Predict Human Effects in Mechanistic and Theoretical Studies"
6:40 pm - 6:50 pmDiscussion
6:50 pm - 7:20 pmSander van den Driesche (MRC Centre for Reproductive Health, Edinburgh UK)
"Species Differences in Susceptibility to Testosterone Inhibition"
7:20 pm - 7:30 pmDiscussion
7:30 pm - 7:50 pmRavinder Anand-Ivell (University of Nottingham, UK)
"A Large Case Male Reproduction Control Study of Human Pregnancy Links Amniotic Fluid INSL3 to Phthalate load, Smoking, and Cryptorchidism"
7:50 pm - 8:00 pmDiscussion
8:00 pmDinner
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmThyroid and Neurodevelopment
9:00 am - 9:05 amDiscussion Leader: Tom Zoeller (U. Mass)
"Introduction"
9:05 am - 9:35 amJean-Baptiste Fini (CNRS, France)
"How EDCs Affect Thyroid Signaling at the Whole Organism and Cellular Levels and the Development of Humanized Model Organism Bioassays"
9:35 am - 9:45 amDiscussion
9:45 am - 10:05 amSelected from GRS Posters: Stephanie Degroote (Sherbrooke University)
"Perinatal Exposure to a Mixture of Common Phthalates and Flame Retardants at Low Doses Leads to Autistic Traits in Lewis Rats"
10:05 am - 10:15 amDiscussion
10:15 amCoffee Break
10:30 am - 11:00 amDavid Sharlin (Minnesota State University)
"EDCs Thyroid Hormone Action and Auditory Development in Animal Models"
11:00 am - 11:10 amDiscussion
11:10 am - 11:40 amTomas Trnovec (Slovak Medical University, Slovakia)
"PCBs Thyroid Disruption and Hearing in Humans"
11:40 am - 11:50 amDiscussion
11:50 am - 12:20 pmSusan Schantz (Unversity of Illinois)
"Developmental PCB Exposure, Thyroid Disruption and Altered Sensitivity to Audiogenic and Kindling-Induced Seizures"
12:20 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:30 pmFree Time
4:30 pm - 6:00 pmPoster Session
6:00 pm - 8:00 pmThyroid Disruption in Wildlife
6:00 pm - 6:10 pmDiscussion Leader: Barbara Demeneix (Centre National de Recherche, Paris, France)
"Introduction"
6:10 pm - 6:40 pmCaren Helbing (U. Victoria, Canada)
"Chilling Insights into Thyroid Hormone Disruption in Frogs"
6:40 pm - 6:50 pmDiscussion
6:50 pm - 7:20 pmChristy Morrissey (University of Saskatchewan, Canada)
"Impairment of Migration Behaviour and Activity in Birds - Potential Role of EDCs Affecting Global Declines of Migratory Species"
7:20 pm - 7:30 pmDiscussion
7:30 pm - 7:50 pmSelected from GRS Presentations: Ann Petersen (University of Oregon)
"Gonads, Goiters, Genes and Genomes: An Integrative Approach to Understanding the Molecular Basis of Developmental Abnormalities Caused by Environmental Contaminants"
7:50 pm - 8:00 pmDiscussion
8:00 pmDinner
THURSDAY
7:30 am - 8:30 amBreakfast
8:30 am - 9:00 amBusiness Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pmEndocrine Disruption, Obesity and Metabolism
9:00 am - 9:05 amDiscussion Leader: Jerry Heindel (NIEHS, USA)
"Introduction"
9:05 am - 9:35 amJuliette Legler (VU University, Amsterdam)
"OBELIX: Developmental Exposure to Obesogens and Their Effects"
9:35 am - 9:45 amDiscussion
9:45 am - 10:05 amHeli Routti (Norwegian Polar Institute)
"Does Contaminant Exposure Interfere with Polar Bears' Ability to Sustain Climate Change?"
10:05 am - 10:15 amDiscussion
10:15 amCoffee Break
10:30 am - 11:00 amRichard Phipps (U. Rochester)
"Environmental Obesogens and Skewing of Fibroblasts Towards Fat Cells"
11:00 am - 11:10 amDiscussion
11:10 am - 11:40 amMike Ross (UCLA)
"Developmental Programming of Obesity by Maternal Nutrient and EDC Acting via Effects on Adipogenesis and Control of Appetite and Satiety"
11:40 am - 11:50 amDiscussion
11:50 am - 12:20 pmMichele La Merrill (University of California at Davis)
"Perinatal DDT Exposure Impairs Energy Expenditure and Metabolism in Adult Female Mice"
12:20 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:30 pmFree Time
4:30 pm - 6:00 pmPoster Session
6:00 pm - 8:00 pmEDCs and Immunity
6:00 pm - 6:10 pmDiscussion Leader: Brenda Eskenazi (Berkeley, USA)
"Introduction"
6:10 pm - 6:40 pmPaige Lawrence (U. Rochester)
"Early Life Exposures to EDCs Change the Programming of the Immune System via Epigenetic Mechanisms"
6:40 pm - 6:50 pmDiscussion
6:50 pm - 7:10 pmTine Hectors (University of California, Irvine)
"Old Chemicals, New Mechanism: The Steroid and Xenobiotic Receptor (SXR) as a Mechanistic Link Between Polychlorinated Biphenyls and Non-Hodgkin's Lymphoma?"
7:10 pm - 7:20 pmDiscussion
7:20 pm - 7:50 pmPhilippe Grandjean (U. Southern Denmark)
"Immune System Dysfunction in Children Exposed to Endocrine Disrupting Substances"
7:50 pm - 8:00 pmDiscussion
8:00 pmDinner
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDeparture

Last Updated: July 16, 2014
 
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