The Gordon Research Seminar on Endothelial Cell Phenotypes in Health & Disease is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.
The focus of this meeting is the biology of vascular and lymphatic endothelial cells during normal and pathological conditions. In addition to angiogenesis, inflammation, and permeability, the Seminar will feature a wide-range of topics including signaling, gas/lipid regulation, stem cells, and translational applications in the vasculature.
|1:30 pm - 4:30 pm||Arrival and Check-in|
|3:00 pm - 3:15 pm||Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair|
|3:15 pm - 4:00 pm||Keynote Session|
|Discussion Leader: S. Ananth Karumanchi (Beth Israel Deaconess Medical Center)|
|3:15 pm - 3:45 pm ||Victoria Bautch (University of North Carolina at Chapel Hill)
"BMP and Blood Vessels: Tip Cells Revisited"
|3:45 pm - 4:00 pm ||Discussion|
|4:00 pm - 5:30 pm||Poster Session I|
|5:30 pm - 7:30 pm||Angiogenesis and Endothelial Signalling|
|Discussion Leader: Christiana Ruhrberg (University College London)|
|5:30 pm - 5:45 pm ||Ana Bastos de Carvalho (University of Kentucky)|
"IgG1 Antibodies Suppress Angiogenesis via Fc Gamma Receptor I and c-Cbl Activation"
|5:45 pm - 5:50 pm ||Discussion|
|5:50 pm - 6:05 pm ||Jennifer Esser (Freiburg University)|
"BMP4-Regulated MicroRNAs Are in Control of Endothelial Cell Function in Angiogenesis"
|6:05 pm - 6:10 pm ||Discussion|
|6:10 pm - 6:25 pm ||Anjali Kusumbe (Max Planck Institute for Molecular Biomedicine)|
"Coupling of Angiogenesis and Osteogenesis by a Specific Vessel Subtype in Bone"
|6:25 pm - 6:30 pm ||Discussion|
|6:30 pm - 6:45 pm ||Marcella Faria (Butantan Institute)|
"The SVMP Bothropasin by Means of Its Disintegrin-Like/Cysteine-Rich Domain Can Modulate Endothelial Cell Proliferation, Migration, and Adhesion to Collagen I in an Integrin alpha2beta-Dependent Manner"
|6:45 pm - 6:50 pm ||Discussion|
|6:50 pm - 7:05 pm ||Claudio Raimondi (University College London)|
"Imatinib Inhibits VEGF-Independent Angiogenesis by Targeting NRP1-Dependent ABL1 Activation in Endothelial Cells"
|7:05 pm - 7:10 pm ||Discussion|
|7:10 pm - 7:25 pm ||Bradley Gelfand (University of Kentucky)|
"Dual, Opposing Roles for Dicer in Angiogenesis"
|7:25 pm - 7:30 pm ||Discussion|
|7:30 am - 8:30 am||Breakfast|
|9:00 am - 11:00 am||Stem Cells, Tumor Vasculature, and Translational Applications|
|Discussion Leader: Victoria Bautch (University of North Carolina at Chapel Hill)|
|9:00 am - 9:15 am ||Sunder Sims-Lucas (Children's Hospital of Pittsburgh)|
"Kidney Derived Endothelial Progenitors Play a Critical Role During Development and Kidney Injury"
|9:15 am - 9:20 am ||Discussion|
|9:20 am - 9:35 am ||Lin Xiao (University of North Carolina at Chapel Hill)|
"Tumor Endothelial Cells with Distinct Patterns of TGFβ-Driven Mesenchymal Differentiation"
|9:35 am - 9:40 am ||Discussion|
|9:40 am - 9:55 am ||Olivia Lenoir (INSERM)|
"Endothelial Autophagy During Microvascular Complications of Diabetes"
|9:55 am - 10:00 am ||Discussion|
|10:00 am - 10:15 am ||Priscilla Williams (University of California, Davis)|
"Investigating the Role of Sphingosine-1-Phosphate and Hypoxia on Mature and Progenitor Endothelial Cells"
|10:15 am - 10:20 am ||Discussion|
|10:20 am - 10:35 am ||Christopher Moxon (University of Liverpool)|
"Endothelial Protein C Receptors and Cerebral Malaria"
|10:35 am - 10:40 am ||Discussion|
|10:40 am - 10:55 am ||Veronica Steri (University of East Anglia)|
"Elucidating the Role of Endothelial β3-Integrin in Tumour Metastasis"
|10:55 am - 11:00 am ||Discussion|
|11:00 am - 12:30 pm||Poster Session II|
|Coffee will be served in the poster area from 11:00 am - 11:30 am|
|1:30 pm - 2:30 pm||Inflammation, Gas/Lipid Regulation and Vascular Permeability|
|Discussion Leader: Zoltan Arany (Beth Israel Deaconess Medical Center)|
|1:30 pm - 1:45 pm ||Andrea Liebl (University Medical Center, Erlangen)|
"SPARCL1 Is Up-Regulated in Tumor Endothelial Cells Isolated from Th1-Like Colorectal Carcinomas and Contributes to Immune Angiostasis"
|1:45 pm - 1:50 pm ||Discussion|
|1:50 pm - 2:05 pm ||Peter Westenskow (The Scripps Research Institute)|
"Cone Photoreceptors Generate the Fatty Acid Amide Erucamide for Maintenance of the Ocular Vasculature"
|2:05 pm - 2:10 pm ||Discussion|
|2:10 pm - 2:25 pm ||Lisa Haep (University Medical Center, Erlangen)|
"Plasticity of Endothelial Cell Phenotypes in Inflammatory Bowel Disease-Associated Angiogenesis"
|2:25 pm - 2:30 pm ||Discussion|
|2:30 pm - 3:00 pm||Evaluation Period|
|Fill in GRS Evaluation Forms|
|3:00 pm||Seminar Concludes|