Gordon Research Conferences
Meeting Details

Myelin (GRS)
Gordon Research Seminar

Myelin Development and Disease


March 22-23, 2014


Ventura Beach Marriott
Ventura, CA


Brad Zuchero

Associate Chair:
Linde Kegel

Meeting Description

The Gordon Research Seminar on Myelin is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The aim of this meeting is to bring together young scientists to explore the mechanisms driving myelination in the central and peripheral nervous systems, and why this fails in demyelinating disease. The meeting will feature a mentorship component, and scientific sessions will highlight current thinking on the development and cell biology of myelinating glia, myelin disease, and remyelination.

Related Meeting

This GRS was held in conjunction with the "Myelin" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.


Meeting Program

2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session
Discussion Leader: Andrew Jarjour (University of Edinburgh, UK)
3:45 pm - 4:15 pmKlaus-Armin Nave (Max Planck Institute, Göttingen, Germany)
"Novel Roles of Myelinating Glial Cells in Axonal Energy Metabolism"
4:15 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session I
6:00 pmDinner
7:30 pm - 9:30 pmOligodendrocyte and Progenitor Dynamics and Plasticity
Discussion Leaders: Kelly Monk (Washington University, St. Louis, USA) and Michelle Monje (Stanford University, USA)
7:30 pm - 7:50 pmEthan Hughes (Johns Hopkins University, USA)
"Oligodendrocyte Dynamics in Cortical Gray Matter"
7:50 pm - 8:00 pmDiscussion
8:00 pm - 8:20 pmErin Gibson (Stanford University, USA)
"Adaptive White Matter: Neuronal Activity Promotes Oligodendrogliogenesis and Myelination in the Mammalian Brain"
8:20 pm - 8:30 pmDiscussion
8:30 pm - 8:50 pmFrancesca Vigano (Ludwig-Maximilians University, Germany)
"New Insights into the Heterogeneity of Adult NG2-Glia"
8:50 pm - 9:00 pmDiscussion
9:00 pm - 9:20 pmCody Smith (University of Virginia, USA)
"CNS-Derived Glial Cells Restrict the Myelinating Glial Cells of the CNS/PNS Transition Zone to Their Domains"
9:20 pm - 9:30 pmDiscussion
7:30 am - 8:30 amBreakfast
9:00 am - 10:30 amCell Biological Mechanisms of Myelination
Discussion Leaders: Sharyl Fyffe-Maricich (University of Pittsburgh, USA) and Stacey Wahl (Rutgers University, USA)
9:00 am - 9:20 amYannick Poitelon (Hunter James Kelly Research Institute, University at Buffalo, USA)
"Spatial Mapping of Juxtacrine Axo-Glial Interactions Reveals Novel Molecules in Myelination"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amRuani Fernando (Institut des Neurosciences de Montpellier, INSERM, France)
"Myelin Sheath Extension in Schwann Cells is Linked to Limb Elongation via YAP"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amEmily Mathews (University of Colorado Anschutz Medical Campus, USA)
"The Cholesterol Biosynthetic Pathway is Required for Oligodendrocyte Migration, Axon Wrapping and Myelin Gene Expression"
10:20 am - 10:30 amDiscussion
10:30 am - 10:50 amSarah Petersen (Washington University, St. Louis, USA)
"The Adhesion GPCR Gpr126 Has Distinct, Domain-Dependent Functions in Schwann Cells During Radial Sorting and Myelination Governed by Interaction with Laminin-211"
10:50 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session II
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:45 pmNovel Approaches to Study Myelin Disease and Regeneration
Discussion Leaders: David Rowitch (University of California, San Francisco, USA) and Andrew Robinson (Northwestern University, USA)
1:30 pm - 1:45 pmAbbe Crawford (University of Cambridge, UK)
"Does the Developmental Heterogeneity of Oligodendrocyte Origin Influence Remyelination of the Adult Central Nervous System?"
1:45 pm - 1:55 pmDiscussion
1:55 pm - 2:10 pmFeng Mei (University of California, San Francisco, USA)
"Micropillar Arrays as a High-Throughput Screening Platform for Therapeutics in Multiple Sclerosis"
2:10 pm - 2:20 pmDiscussion
2:20 pm - 2:35 pmRobert Fledrich (Max Planck Institute, Göttingen, Germany)
"Soluble Neuregulin1 Targets Schwann Cell Dysdifferentiation in Rodent Models of Charcot-Marie-Tooth Disease 1A (CMT1A)"
2:35 pm - 2:45 pmDiscussion
2:45 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes

Research reported in this publication was supported by the National Institute Of Neurological Disorders And Stroke of the National Institutes of Health under Award Number 13NS086113. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
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