Gordon Research Conferences
Meeting Details

Synaptic Transmission (GRS)
Gordon-Kenan Research Seminar

From Molecular Machines to Local Circuit Function


August 2-3, 2014


Waterville Valley
Waterville Valley, NH


Thomas J. Younts

Associate Chair:
James A. Daniel

Meeting Description

The inaugural Gordon Research Seminar (GRS) on Synaptic Transmission: From Molecular Machines to Local Circuit Function provided a unique opportunity for junior scientists to present and exchange new data and cutting-edge ideas. We united an outstanding, international group of young investigators from over 12 different countries working at the forefront of synaptic transmission!

The primary aims of our GRS were to: (1) provide a two-day forum for like-minded graduate students, post-docs, and other scientists to present state-of-the-art research findings during informal talks, scientific discussion sessions, and poster presentations; (2) launch long-term collaborations that will ultimately facilitate how the field understands synaptic transmission; (3) allow motivated young investigators to share and learn about information that may augment their research projects and those around them; (4) offer a low-pressure environment for exchange of knowledge and to promote intellectual and social dialogue with senior attendees at the GRS and associated GRC; (5) increase diversity and presence of under-represented minorities, in particular women, in basic and translational neuroscience research; (6) advance young scientists' careers and international networks while providing a venue for professional development; and (7) have fun!

The meeting featured a Keynote Lecture, eight Graduate Student/Post-doc Talks with ample discussion time, two Poster Sessions, a Neuroscience Social, and a Career Development Panel from three diverse and engaging scientists at different career and life stages. All attendees were expected to actively participate in the GRS either by giving an oral presentation, leading a discussion, asking questions during the talks, networking with colleagues, and/or presenting a poster.

The 2014 meeting was both personally and professionally rewarding for the scientists involved, providing an ideal platform to discuss the most exciting discoveries in the field. It is our hope that the GRS on Synaptic Transmission remains one of the top neuroscience meetings in the world for young investigators! Please thank the organizations listed below by visiting their web-site because their financial contributions helped ensure this very first GRS' success!

Related Meeting

This GRS was held in conjunction with the "Synaptic Transmission" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.


Meeting Program

1:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session
Discussion Leader: Kristen Harris (The University of Texas at Austin)
3:45 pm - 4:15 pmErik Jorgensen (Howard Hughes Medical Institute, University of Utah)
"Ultrafast Endocytosis at Synapses"
4:15 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session I (GRS Participants with Last Names A-M Present Their Posters)
6:00 pmDinner
7:30 pm - 9:30 pmMolecular and Cellular Mechanisms of Synaptic Transmission
Discussion Leaders: Mathew Klein (Albert Einstein College of Medicine) and Jennifer Deem (University of Washington)
7:30 pm - 7:50 pmAdina Buxbaum (Albert Einstein College of Medicine)
"Altered Single Beta-Actin mRNA Detection at Synapses During cLTP Reveals a Mechanism for Regulating Its Translation"
7:50 pm - 8:00 pmDiscussion
8:00 pm - 8:20 pmNatalia Luchkina (University of Helsinki, Finland)
"Long-Term Potentiation in Developing Hippocampus: Role of GluA4"
8:20 pm - 8:30 pmDiscussion
8:30 pm - 8:50 pmGyorgy Lur (Yale School of Medicine)
"Neuromodulation of Glutamatergic Transmission in Synaptic Microdomains"
8:50 pm - 9:00 pmDiscussion
9:00 pm - 9:20 pmBorislav Dejanovic (University of Cologne, Germany)
"Palmitoylation of Gephyrin Controls Receptor Clustering and Synaptic Plasticity of GABAergic Synapses"
9:20 pm - 9:30 pmDiscussion
9:30 pm - 12:00 amNeuroscience Social
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amSynaptic Transmission in Microcircuits
Discussion Leaders: Sarah Leinwand (University of California, San Diego) and Christopher Vaaga (Oregon Health and Science University)
9:00 am - 9:20 amFiona Muellner (Max Planck Institute of Neurobiology, Germany)
"Individual GABAergic Synapses Inhibit Dendritic Calcium Transients with High Temporal and Spatial Precision"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amLaura Knogler (Research Centre of the University of Montreal Hospital Centre, Canada)
"A Hybrid Electrical and Chemical Circuit in the Developing Spinal Cord Generates a Novel Transient Embryonic Motor Behavior"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amAbigail Gambrill (The Scripps Research Institute)
"Intertectal Inputs Modulate Developing Circuit Plasticity in the Xenopus Optic Tectum"
10:20 am - 10:30 amDiscussion
10:30 am - 10:50 amSrikanth Ramaswamy (Mind Brain Institute, Switzerland)
"In Silico Synaptic Transmission in a Reconstruction of a Neocortical Microcircuit: Principles and Predictions"
10:50 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session II (GRS Participants with Last Names N-Z Present Their Posters)
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component
Professional and Career Development Discussion Panel:
  • Nils Brose (Max Planck Institute for Experimental Medicine, Germany)
  • Kristen Harris (The University of Texas at Austin)
  • Alma Rodenas-Ruano (Albert Einstein College of Medicine)
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes

Research reported in this publication was supported by the National Institute of Neurological Disorders And Stroke of the National Institutes of Health under Award Number R13NS086292. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
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