Applications for this meeting must be submitted by April 20, 2014. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.
The NOX Family NADPH Oxidases Gordon Research Conference will be held in conjunction with the NOX Family NADPH Oxidases Gordon Research Seminar
. Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Please refer to the NOX Family NADPH Oxidases GRS web page for more information.
The GRC on NOX Family NADPH Oxidases features cutting-edge unpublished work presented by international experts across the NOX field, and will be preceded for the second time by a NOX Gordon Research Seminar for research trainees, graduate students and post-doctoral fellows. NOX family proteins are now known to be major sources of reactive oxygen species (ROS) in most mammalian cell types as well as in diverse species such as fish and plants. They are highly regulated enzymes that in recent years have been implicated in an extremely wide array of physiological and pathophysiological processes. The science in the field is moving dramatically fast with exciting advances in many areas, from basic biochemistry of the enzymes, dissection of molecular signalling events and cell biology, to the delineation of NOX isoform-specific functions in new in vivo models, human studies and therapeutic development. The 2-yearly NOX GRC is firmly established as the premier forum for the presentation and discussion of the latest advances in the field in a highly collegiate, collaborative and informal atmosphere.
The programme for the 2014 NOX GRC has been developed around the theme "From NOX mechanisms to disease". Session topics include NOX biochemistry and structure, a focus on NOX-dependent signalling, non-mammalian NOXs, immune functions of NOXs, and disease-oriented translational topics such as cancer, cardiovascular and central nervous disease. We expect exciting, timely and paradigm-challenging presentations in this accelerating field, with ample time for vigorous discussion after each talk. Poster sessions will be ideal opportunities for more prolonged discussion and the active involvement of earlier career investigators. The programme also allows for the inclusion of novel late-breaking science. Attracting a diverse group of male and female participants is a major priority for the meeting. The accompanying GRS programme features speakers selected from among trainee abstracts, as well as career development components and mentoring by senior scientists. Do not miss these NOX meetings!
The conference also gratefully acknowledges a personal contribution from: Francisco Laurindo.
A list of preliminary session topics and speakers is displayed below (discussion leaders, where known, are noted in italics). The detailed program is currently being developed by the Conference Chair and will be available by January 18, 2014. Please check back for updates.
- NOX-Dependent Signalling and Molecular Targets
(Chihiro Yabe-Nishimura / Richard Cohen / Lars Maier / Albert Van der Vliet)
- Structure and Biochemistry of NOXs
(Mary Dinauer / Becky Diebold / Franck Fieschi / Jamel El-Benna)
- Immune and Defense Functions of NOXs
(Nathalie Grandvaux / Luigina Romani / Brahm Segal / Asma Nusrat / Janice Blum)
- Redox Proteomics and Imaging
(Phil Eaton / Kate Carroll / Chris Chang / Leslie Poole)
(Kathy Griendling / Allen Cowley / Rhian Touyz / Ira Tabas)
(Francisco Laurindo / James Doroshow / Tohru Kamata / Corinne Dupuy)
- Central Nervous System
(Karl-Heinz Krause / Marga Behrens / Raymond Swanson / Achim Schmidtko)
- Non-Mammalian and Plant NOXs
(Dave Lambeth / Jorg Kudla / Anne Huttenlocher / Enrique Amaya)
- NOX Biology in Humans
(Ralf Brandes / Francesco Violi / A George / Karl Lackner)