Conference Program
 
FERTILIZATION & ACTIVATION OF DEVELOPMENT

July 27 - August 1, 2003
Holderness School
Holderness, NH

Chair:
Jurrien Dean

Vice Chair:
Richard A. Cardullo

We wish to acknowledge generous financial support from:

The Lalor Foundation
Wyeth Laboratories
Ernst Schering Research Foundation GMBH
The Serono Foundation
GRC Miniorty Participants Funding
National Institutes of Health


SUNDAY
2:00 pm - 9:00 pmArrival and Check-in
5:00 pm - 6:00 pmReception
6:00 pmDinner
7:30 pm - 9:30 pmAlternative Reproductive Strategies
Discussion Leader: JOHN EPPIG (The Jackson Laboratory)
JOHN EPPIG
Introduction
JEAN PAUL RENARD (Unite de Biologie du Developement INRA)
"Reprogramming nuclear activities during early rabbit embryonic development"
TOMOHIRO KONO (Tokyo University of Agriculture)
"Progress of nuclear competence in oogenesis"
HANS SCHOLER (University of Pennsylvania)
"Oocytes from mouse embryonic stem cells"
MONDAY
7:30 am - 8:30 amBreakfast
8:45 amGroup Photo
9:00 am - 12:30 pmSperm-egg Interactions
Discussion Leader: RICHARD CARDULLO (University of California, Riverside)
RICHARD CARDULLO
Introduction
ELIZABETH LORD (University of California, Riverside)
"Adhesion molecules involved in pollen tube guidance"
MICHAEL ENSSLIN (Emory University)
"SED1, an EGF repeat and discoidin-domain protein involved in mouse sperm-egg binding"
TANYA HOODBHOY (National Institutes of Health)
"Persistent taxon-specific sperm binding to chimeric human-mouse zonae pellucidae"
WILLIE SWANSON (University of Washington)
"Life in the fast lane: functional inferences from rapidly evolving reproductive proteins"
12:30 pmLunch
6:00 pmDinner
7:30 pm - 9:30 pmSperm Signal Transduction
Discussion Leader: VIC VACQUIER (Scripps Institute of Oceanography)
VIC VACQUIER
Introduction
VIC VACQUIER
"Egg ligands, sperm receptors and the sea urchin sperm acrosome reaction"
DAVID CLAPHAM (Harvard Medical School, HHMI)
"The role of CatSper ion channels in sperm motility"
ANDY SINGSON (Wakesman Institute, Rutgers University)
"Mutants that affect gamete function at fertilization in C. elegans"
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmSperm-egg Membrane Interactions
Discussion Leader: SHEILA MCCORMICK (University of California, Berkeley)
SHEILA MCCORMICK
Introduction
UELI GROSSNIKLAUS (University of Zurich)
"Maternal effects on seed development in Arabidopsis"
PAUL PRIMAKOFF (University of California, Davis)
"Mouse Sperm-Egg Fusion"
SHEILA MCCORMICK (University of California, Berkeley)
"Functional analyses of plant gamete gene expression"
KENJI MIYADO (Osaka University Medical School)
"Tetraspanins and gamete membrane fusion"
12:30 pmLunch
6:00 pmDinner
7:30 pm - 9:30 pmKeynote Address
DAVID C. PAGE (Whitehead Institute, HHMI, MIT)
"Human infertility and the Y Chromosome"
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmEvents of Egg Activation
Discussion Leader: DIANE SHAKES (College of William and Mary)
DIANE SHAKES
Introduction
ANDY GOLDEN (National Institutes of Health)
"The Myt1 ortholog in C. elegans is essential for normal oocyte development and maturation"
JEAN-PIERRE OZIL (Institut National de la Rechereche Agronomique)
"Oocyte activation: The root of things"
PETER JACKSON (Stanford University)
"CSF arrest in meiosis II by the anaphase promoting complex regulator Emi1"
RICHARD CARTHEW (Northwestern University)
"RNA interference and egg activation"
12:30 pmLunch
6:00 pmDinner
7:30 pm - 9:30 pmPaternal Effects
Discussion Leader: BARBARA WAKIMOTO (University of Washington)
BARBARA WAKIMOTO
Introduction
TIM KARR (University of Chicago)
"Molecular mechanism(s) of wolbachia-induced sexual incompatibility in Drosophila"
BARBARA WAKIMOTO (University of Washington)
"Genetic dissection of paternal effects and sperm activation pathways in Drosophila"
TBA - POSTER TALKS
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmMaternal Effects
Discussion Leader: MARIANNA WOLFNER (Cornell University)
MARIANNA WOLFNER
Introduction
CHARLES GLABE (University of California, Irvine)
"Species-specific gamete adhesion is mediated by EBR1, the egg surface receptor for bindin"
MARY MULLINS (University of Pennsylvania)
"Maternal control of vertebrate embryonic development: mutant studies from the zebrafish"
HOWARD LIPSHITZ (Hospital for Sick Children)
"Regulation of maternal transcripts during egg activation in Drosophila"
KENNETH KEMPHUES (Cornell University)
"Establishing embryonic polarity in C. elegans"
12:30 pmLunch
6:00 pmDinner
7:30 pm - 9:30 pmEstablishment of Embryonic Polarity
Discussion Leader: RICHARD SCHULTZ (University of Pennsylvania)
RICHARD SCHULTZ
Introduction
LESILEE ROSE (University of California, Davis)
"Cell polarity and spindle positioning in C. elegans"
MAGDALENA ZERNICKA-GOETZ (University of Cambridge)
"Early patterning in the mouse embryo"
BERNARD MARO (CNRS, Université Pierre et Marie Curie)
"Cell polarity and cell interactions control blastocyst morphogenesis during mouse early embryogenesis"
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDepart

Last Updated: May 4, 2006