Conference Program
 
STRUCTURAL, FUNCTIONAL & EVOLUTIONARY GENOMICS

June 19-24, 2005
Bates College
Lewiston, ME

Chair:
Kevin White

Vice Chair:
Eugene Koonin

This Gordon conference will cover the areas of structural, functional and evolutionary genomics. It will take a systematic approach to genomics, examining the control and evolution of developmental and physiological systems in the context of genetic and biochemical networks. Emphasis will be placed on what we can learn from comparative genomics and entire genomes and proteomes.

Genomics and Bioinformatics research is of great significance to the biomedical community. The genome projects and the development of technologies for high throughput genetic and molecular analyses are accelerating almost every area of biological investigation. This conference provides a unique forum that unites leading researchers in computational, experimental and theoretical areas of genome science. The subject is intentionally broad and diverse, and leads to intimate exposure of researchers from various subfields of genome science to one another's work. As a result, the atmosphere of this conference is very dynamic and interdisciplinary. Graduate students and post-docs are highly encouraged to apply.

There will be a limited number of fellowship awards of $660 for graduate students and postdocs (no more than 3 years past the date of their PhD at the time of the meeting) who submit a highly meritorious abstract to present a poster. Abstracts received before midnight on May 28 will be reviewed for scientific merit by the chairs and vice-chairs of this meeting and ranked. The recipients of these awards will be announced within a week of the deadline. Please submit your abstract with your application to the conference at the GRC web-site and also contact Audrey Meusel (audrey.meusel@yale.edu) to let the conference chairs know that you want to be considered for a fellowship award. Applicants (student, post doc, faculty or research scientist working at a U.S. institution) who belong to an underrepresented minority are encouraged strongly to apply.


SUNDAY
2:00 pm - 9:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 9:30 pmFunctional Genomics I: Developmental Genomics
Discussion Leader: Eric Siggia (Rockefeller University)
7:30 pm - 8:10 pmUlrike Gaul (Rockefeller University)
"Reparsing segmentation - transcriptional and translational control of early body patterning in drosophila"
8:10 pm - 8:50 pmAlan Michelson (Harvard University).
"An integrated genomic approach to the transcriptional regulation of mesoderm development in Drosophila"
8:50 pm - 9:30 pmChris Burge (MIT)
"Prediction of vertebrate microRNA targets"
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmProteins and Proteomes I: Predicting protein interactions
Discussion Leader: Cyrus Chothia (MRC Laboratory of Molecular Biology)
9:00 am - 9:45 am Joël Janin (University of Paris)
"Principles of Protein-Protein Recognition"
9:45 am - 10:15 amCoffee Break / Photo (10:00)
10:15 am - 11:00 amJeffrey J. Gray (Johns Hopkins University)
"The Prediction of the Structure of Protein-Protein Recognition Sites"
11:00 am - 11:45 am Siarhei Maslau (MRC Laboratory of Molecular Biology)
"The Formation of Novel Protein Functions by Domain Combinations"
11:45 am - 12:30 pmAndrew Emili (University of Toronto)
"Interactomics: What Proteomics Can Teach Us About Bacterial Protein Biology"
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session I
6:00 pmDinner
7:30 pm - 9:30 pmFunctional Genomics II: Approaches to high throughput genetic screening and phenotyping
Discussion Leader: Kevin White (Yale University)
7:30 pm - 8:10 pm Fabio Piano (NYU)
"Automated phenotypic screening and clustering in C. elegans"
8:10 pm - 8:50 pmAmy Kiger (UCSD)
"Identification of genetic and biochemical pathways in Drosophila using automated imaging and RNAi"
8:50 pm - 9:30 pmFrank Buchholz (Max Planck Institute)
"RNAi screening in Mammalian Cells with esiRNA"
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmEvolution of genome complexity
Discussion Leader: Eugene Koonin (NCBI)
9:00 am - 9:45 am Chris Adami (Caltech)
"Inferring the complexity of genes from their sequences"
9:45 am - 10:30 am Arcady Mushegian (Stowers Insitute)
"Similarity measures and similarity searches in genome-wide numeric data sets"
10:30 am - 11:00 amCoffee Break
11:00 am - 11:45 amHunter Fraser (UC Berkeley)
"Evolution of interactions and complexity: a genomic perspective"
11:45 am - 12:30 pm I. King Jordan (NCBI)
"Evolution of amino acid composition and protein complexity"
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session II
6:00 pmDinner
7:30 pm - 9:30 pmEvolution and Biodiversity
Discussion Leader: Doug Brutlag (Stanford University)
7:30 pm - 8:10 pm Ed Delong (MIT)
"Exploring the marine microbial world, from genomes to biomes"
8:10 pm - 8:50 pm Bernard Moret (U. of New Mexico)
"Phylogenetic methods for building the tree of life"
8:50 pm - 9:30 pmPhil Bourne (UCSD)
"Evolution as measured by numbers of protein folds"
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmProteins & Proteomes II: Macromolecular complexes
Discussion Leader: Peer Bork (EMBL)
9:00 am - 9:45 amAndrey Rzhetsky (Columbia University)
"On distributed thinking about molecular networks"
9:45 am - 10:30 amArchilleas Frangakis (EMBL)
10:30 am - 11:00 amCoffee Break
11:00 am - 11:45 amGiulio Superto-Furga (Cellzome)
11:45 am - 12:30 pmNevan Krogan (Best Institute)
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session III
6:00 pmDinner
7:30 pm - 9:30 pmComparative genomics, microevolution, neutralism and selection
Discussion Leader: Yoav Gilad (Brown University)
7:30 pm - 8:10 pm Tony Long (UC Irvine)
"Thousands of flies, hundreds of SNPs, Notch signaling, and the dissection of a complex trait in the wild"
8:10 pm - 8:50 pmMichael Eisen (University of California, Berkeley)
"Understanding and Exploiting the Evolution of Regulatory Sequences"
8:50 pm - 9:30 pmGreg Gibson (NCSU)
"The Quantitative Genetics of Transcription"
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmFunctional Genomics III: Chemical Genomics
Discussion Leader: Joel Bader (Johns Hopkins University)
9:00 am - 9:45 am Ulrike Eggert (Harvard University)
"Parallel chemical genetic and genome-wide RNAi screens"
9:45 am - 10:30 am Guri Giaever (Stanford University)
"Chemical genetics in yeast"
10:30 am - 11:00 amCoffee Break
11:00 am - 11:45 amRandall Peterson (Harvard University)
"Zebrafish chemical genetics - probing differentiation and patterning in the intact vertebrate"
11:45 am - 12:30 pmTimothy Gardner (Boston University)
"Reverse engineering pathways from chemical genomics screens"
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session (if needed)
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Session
7:30 pm - 9:30 pmComparative Functional Genomics
Discussion Leader: Inna Dubchak (Lawrence Berkeley National Lab)
7:30 pm - 8:10 pmDan Rokhsar (UC Berkeley, Joint Genome Institute)
"Natural experiments in whole genome duplication"
8:10 pm - 8:50 pmDario Boffelli (Lawrence Berkeley National Lab)
"Comparative genomics at the vertebrate extremes"
8:50 pm - 9:30 pmAdam Arkin (UC Berkeley, Lawrence Berkeley National Lab)
"Comparative Analysis of Microbial Stress Responses"
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDepart

Last Updated: August 14, 2006