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Streptococcal Biology (GRS)

Gordon Research Seminar

Physiology, Host-Interactions and Vaccine Development and Epidemiology of Streptococci

August 13 - 14, 2022

Chairs Brady L. Spencer and Lamar Thomas

Jordan Hotel at Sunday River

27 Grand Circle

Newry, Maine, United States

Venue and Travel Information

Conference Description

The Gordon Research Seminar on Streptococcal Biology is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The inaugural GRS on Streptococcal Biology will feature the many aspects of current streptococcal/enterococcal research with special emphasis on the physiology, host-pathogen interactions, and vaccine development research being done by graduate students and post-doctoral fellows. Additionally, the GRS will host a panel discussion to further develop attendees’ science communication skills focused on grant writing strategies and public engagement.

Related Meeting

This GRS will be held in conjunction with the "Streptococcal Biology" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm	Keynote Session: Pneumococcal Pathogenesis: Co-opting of Host Factors for Transmission and Disease Discussion Leader: Haider Manzer (University of Colorado - Anschutz Medical Campus, United States)
3:45 pm - 4:20 pm	Carlos Orihuela (The University of Alabama at Birmingham, United States) "Pneumococcal Pathogenesis: Co-Opting of Host Factors for Transmission and Disease"
4:20 pm - 4:30 pm	Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Streptococcus Host-Pathogen Interactions and Physiology Discussion Leaders: Ronni da Silva (Singapore MIT Alliance for Research and Technology, Singapore), Babak Alibayov (University of Mississippi Medical Center, United States) and Elizabeth Tinder (St Jude Children's Research Hospital, United States)
7:30 pm - 7:40 pm	Andrew Nishimoto (St. Jude Children's Research Hospital, United States) "Pneumococcal ß-Lactam Resistance Acquired by Interspecies Recombination Maintains Virulence Compared to De Novo Mutation"
7:40 pm - 7:45 pm	Discussion
7:45 pm - 7:55 pm	Kristin Huse (Imperial College London, United Kingdom) "Soluble M1 Protein Acts as an Antiphagocytic Factor in the Presence of Fibrinogen and Serotype Specific Antibodies"
7:55 pm - 8:00 pm	Discussion
8:00 pm - 8:10 pm	Adeline Supandy (Rice University, United States) "Resistance to Daptomycin-Fosfomycin Combination in Enterococcus faecium Occurred Through Independent Pathways"
8:10 pm - 8:15 pm	Discussion
8:15 pm - 8:25 pm	Julia Derk (CU Denver - Anschutz Medical Campus, United States) "Arachnoid Barrier Breakdown During GBS-Mediated Meningitis Infections"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 8:40 pm	Edroyal Womack (Georgia State University, United States) "Endogenous Hydrogen Peroxide Impacts Iron Availability and Heme Uptake in Streptococcus pneumoniae During Growth on Hemoglobin."
8:40 pm - 8:45 pm	Discussion
8:45 pm - 8:55 pm	Amanda Marple (University of Western Ontario, Canada) "Carbohydrate Metabolism and Niche Competition by Streptococcus pyogenes"
8:55 pm - 9:00 pm	Discussion
9:00 pm - 9:10 pm	Molly Sharp (New York University, United States) "Genetic Determinants of Capsular Polysaccharide Shedding in Group B Streptococcus"
9:10 pm - 9:15 pm	Discussion
9:15 pm - 9:25 pm	Christian Ahearn (University at Buffalo School of Dental Medicine, United States) "Phylogeny of Serine-Rich Repeat Protein Sialic-Acid-Binding Domains Among Members of the Genus Streptococcus"
9:25 pm - 9:30 pm	Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Novel Explorations in Streptococcal Research Discussion Leaders: Magnus Jespersen (The University of Melbourne, Australia), Bharathi Sundaresh (Boston College, United States), Rebecca Keogh (CU Anschutz, United States) and Alexandra Peterson (University of Florida, United States)
9:00 am - 9:10 am	Luke Joyce (University of Colorado Anschutz Medical Campus, United States) "Group B Streptococcal Cellular Membrane Lipids at the Host-Pathogen Interface"
9:10 am - 9:15 am	Discussion
9:15 am - 9:25 am	Mizpha Fernander (North Carolina A&T State University, United States) "Investigating the Genotypic and Phenotypic Adaptations of S. mutans to Microgravity Using Experimental Evolution."
9:25 am - 9:30 am	Discussion
9:30 am - 9:40 am	Vikrant Minhas (University of Lausanne, Switzerland) "Heterogeneous Single-Cell Responses Underlie Host-Pathogen Signaling During Pneumococcal Infection"
9:40 am - 9:45 am	Discussion
9:45 am - 9:55 am	Ariane Neumann (Lund University, Sweden) "Host pathogen protein-protein interactions in Gram-positive anaerobic coccal infections"
9:55 am - 10:00 am	Discussion
10:00 am - 10:10 am	Haris Antypas (Nanyang Technological University, Singapore) "Delineating the neutrophil response in enterococcal infective endocarditis"
10:10 am - 10:15 am	Discussion
10:15 am - 10:25 am	Marlyd Mejia (Baylor College of Medicine, United States) "Using a humanized microbiota mouse model to study the influence of vaginal microbes in Group B Streptococcus reproductive tract colonization"
10:25 am - 10:30 am	Discussion
10:30 am - 10:40 am	Ouli Xie (Peter Doherty Institute for Infection and Immunity, Australia) "Clinical and Genomic Epidemiology of Invasive Group A and C/G Streptococcus in Australia"
10:40 am - 10:45 am	Discussion
10:45 am - 10:55 am	Corine Jackman Burden (Carnegie Mellon University, United States) "Mini-Bioreactors for the Study of Pneumococcal Cell-Cell Communication"
10:55 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Mentorship Component: Science Communication Discussion Leader: Alexander Lewis Marffy (Imperial College London, United Kingdom)
1:30 pm - 2:10 pm	Michael Johnson (University of Arizona/NSURP, United States) "Science Communication: Controlling Your Narrative"
2:10 pm - 2:30 pm	Discussion
2:30 pm - 3:00 pm	Evaluation Period Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm	Seminar Concludes

Contributors

Kelly Doran

Research reported in this publication was supported by the National Institute Of Allergy And Infectious Diseases of the National Institutes of Health under Award Number R13AI169705. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

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Streptococcal Biology

August 11 - 16, 2024

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