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Alcohol and the Nervous System

Gordon Research Conference

Neurobiology of Alcohol Use Disorder and CNS Comorbidities

October 23 - 28, 2022

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Chairs Nicholas W. Gilpin and Patricia H. Janak

Vice Chairs Rajita Sinha and Joyce Besheer

Contact Chairs

Residence Inn at Oxnard River Ridge

2101 West Vineyard Ave

Oxnard, CA, United States

Venue and Travel Information

Application Information

Applications for this meeting must be submitted by September 25, 2022. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the conference chair if more seats become available due to cancellations.

Conference Description

Alcohol Use Disorder (AUD) is highly co-morbid with other CNS disorders that include stress and anxiety disorders, pain, CNS injury and other substance use disorders. Alcohol effects on the CNS also differ according to the age and sex of the affected individual, highlighting the need to understand individual variability in AUDs along with their comorbidities. The program for the 2022 meeting of the Alcohol and the Nervous System Gordon Research Conference will include presentations that focus on basic and clinical research investigating the neurobiology of AUD, especially in the context of these prevalent comorbidities and biological vulnerabilities. The Chairs and Vice Chairs will make it a priority to create a meeting program that includes basic and clinical research, and that is diverse by including presenters stratified across career stage, sex/gender, ethnicity, sexual identity and geographical region. The focus on CNS conditions that are co-morbid with AUD will provide a unique opportunity to create new networking and collaborative opportunities for the Alcohol CNS field.

Related Meeting

This GRC will be held in conjunction with the "Alcohol and the Nervous System" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Conference Program

Sunday
2:00 pm - 9:00 pm	Arrival and Check-in
6:00 pm - 7:00 pm	Dinner
7:30 pm - 7:40 pm	Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm	Keynote Session: Successes and Challenges in Translational Alcohol Research Discussion Leader: Rajita Sinha (Yale Stress Center, USA)
7:40 pm - 8:25 pm	George Koob (National Institute on Alcohol Abuse and Alcoholism, NIH, USA) "The Negative Emotional Side of Alcohol Use Disorder: Implications for Deaths of Despair and the COVID-19 Pandemic"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 9:20 pm	Harriet de Wit (University of Chicago, USA) "Successes and Challenges in Translational Research with Alcohol"
9:20 pm - 9:30 pm	Discussion
Monday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Alcohol Interactions with Stress and Brain Stress Systems Discussion Leader: Jamie Maguire (Tufts University School of Medicine, USA)
9:00 am - 9:15 am	Introduction by Discussion Leader
9:15 am - 9:35 am	Kerry Ressler (Harvard Medical School, USA) "The Intersection of Trauma, PTSD, and Addiction"
9:35 am - 9:45 am	Discussion
9:45 am - 10:05 am	Anushree Karkhanis (Binghamton University - SUNY, USA) "Alcohol Interactions with Adolescent Psychosocial Stress and Mesolimbic Stress Systems"
10:05 am - 10:15 am	Discussion
10:15 am - 10:25 am	Marcus Weera (LSU Health New Orleans, USA) "Lateral Hypothalamus Circuits Mediate Stress-Induced Alterations in Alcohol-Related Behaviors in Rats"
10:25 am - 10:30 am	Discussion
10:30 am - 11:00 am	Coffee Break
11:00 am - 11:20 am	Danny Winder (Vanderbilt University School of Medicine, USA) "Exploring an Insula-BNST Circuit in Mouse and Human: The Struggle is Real"
11:20 am - 11:30 am	Discussion
11:30 am - 11:40 am	Laverne Melon (Wesleyan University, USA) "Neurosteroid Modulation of GABAergic Signaling in the Basolateral Amygdala and Alcohol’s Impact on Affective Switching"
11:40 am - 11:45 am	Discussion
11:45 am - 12:05 pm	Marvin Diaz (Binghamton University, USA) "Prenatal Alcohol Rewires Anxiety Circuits Across Development"
12:05 pm - 12:15 pm	Discussion
12:15 pm - 12:25 pm	Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
3:00 pm - 4:00 pm	The GRC Power Hour™ The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring. Organizers: Jocelyn Richard (University of Minnesota, USA) and James Jentsch (Binghamton University, USA)
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Mechanisms and Pathways Underlying Excessive Alcohol Drinking Discussion Leader: Karla Kaun (Brown University, USA)
7:30 pm - 7:45 pm	Introduction by Discussion Leader
7:45 pm - 8:05 pm	Markus Heilig (Linkoping University, Sweden) "Neurobiological Mechanisms of Individual Vulnerability to Alcohol Addiction-like Behaviors"
8:05 pm - 8:15 pm	Discussion
8:15 pm - 8:35 pm	Adrian Rothenfluh (University of Utah, USA) "Distinct Circuits Promoting and Impeding Alcohol Drinking in Drosophila"
8:35 pm - 8:45 pm	Discussion
8:45 pm - 8:55 pm	Reginald Cannady (North Carolina Agricultural and Technical State University, USA) "Key Neuronal Substrates of Increased Alcohol Intake"
8:55 pm - 9:00 pm	Discussion
9:00 pm - 9:20 pm	Angela Ozburn (Oregon Health and Science University, USA) "Neural Substrates of Binge Drinking"
9:20 pm - 9:30 pm	Discussion
Tuesday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Group Photo
9:00 am - 12:30 pm	Executive Control and Flexibility in Alcohol Actions Discussion Leader: Cody Siciliano (Vanderbilt University School of Medicine, USA)
9:00 am - 9:15 am	Introduction by Discussion Leader
9:15 am - 9:35 am	Charlotte Boettiger (University of North Carolina at Chapel Hill, USA) "Alcohol Misuse, Behavioral Flexibility, and Excitatory/Inhibitory Balance in Control Circuitry"
9:35 am - 9:45 am	Discussion
9:45 am - 10:05 am	Christina Gremel (University of California, San Diego, USA) "Chronic Alcohol Exposure Disrupts Behavioral Flexibility via Hyperactive Premotor Corticostriatal Activity"
10:05 am - 10:15 am	Discussion
10:15 am - 10:25 am	Michael Salling (Louisiana State University Health Sciences Center, USA) "Vulnerability of Corticothalamic Function in Rodent Models of ADHD and Adolescent Alcohol Abuse"
10:25 am - 10:30 am	Discussion
10:30 am - 11:00 am	Coffee Break
11:00 am - 11:20 am	Christina Perry (Florey Institute of Neuroscience and Mental Health, Australia) "Reversal Learning Deficits Following Chronic Alcohol: Does this Translate to a Change in Relapse Propensity?"
11:20 am - 11:30 am	Discussion
11:30 am - 11:40 am	Rafiq Huda (Rutgers University, USA) "Prefrontal Cortical Modulation of Pupil-Linked Arousal and Binge-Like Drinking"
11:40 am - 11:45 am	Discussion
11:45 am - 12:05 pm	David Moorman (University of Massachusetts, Amherst, USA) "Impact of Alcohol and Stress on Frontal Cortical Networks Underlying Cognitive Control"
12:05 pm - 12:15 pm	Discussion
12:15 pm - 12:25 pm	Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	New Tools for Biomedical Alcohol Research Discussion Leader: Kevin Bender (University of California, San Francisco, USA)
7:30 pm - 7:45 pm	Introduction by Discussion Leader
7:45 pm - 8:05 pm	Keri Martinowich (Lieber Institute for Brain Development, USA) "Cell-Type and Spatially Resolved Molecular Signatures Across Reward Circuits in the Human Brain"
8:05 pm - 8:10 pm	Discussion
8:10 pm - 8:30 pm	Jacqueline Barker (Drexel University College of Medicine, USA) "Targeting Astrocytes in the Regulation of Reward Seeking"
8:30 pm - 8:35 pm	Discussion
8:35 pm - 8:55 pm	Rajani Maiya (Louisiana State University Health Sciences Center-New Orleans, USA) "Role of the Transcriptional Regulator LMO4 in Alcohol Consumption"
8:55 pm - 9:00 pm	Discussion
9:00 pm - 9:10 pm	Daniel Castro (Washington University in St. Louis, USA) "Next Generation Approaches for Investigating Neuropeptidergic Circuits in Reward and Motivation"
9:10 pm - 9:15 pm	Discussion
9:15 pm - 9:25 pm	Barbara Juarez (University of Washington, USA) "Gene-editing Approaches to Understand Neuronal and Circuit Function in Behavior"
9:25 pm - 9:30 pm	Discussion
Wednesday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Alcohol Interactions with Pain Discussion Leader: Imad Damaj (Virginia Commonwealth University , USA)
9:00 am - 9:15 am	Introduction by Discussion Leader
9:15 am - 9:35 am	Katie Witkiewitz (University of New Mexico, USA) "Chronic Pain and Alcohol Use: Future Directions for Treatment"
9:35 am - 9:45 am	Discussion
9:45 am - 10:05 am	Scott Edwards (LSU Health Sciences Center, USA) "Intersecting Mechanisms and Treatment Opportunities for Pain and Alcohol Use Disorder"
10:05 am - 10:15 am	Discussion
10:15 am - 10:25 am	Short Talk Selected from Poster Abstracts
10:25 am - 10:30 am	Discussion
10:30 am - 11:00 am	Coffee Break
11:00 am - 11:20 am	Yarimar Carrasquillo (National Institutes of Health, USA) "Amygdala Circuits for Bidirectional Control of Pain"
11:20 am - 11:30 am	Discussion
11:30 am - 11:40 am	Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am	Discussion
11:45 am - 12:05 pm	Thomas Kash (University of North Carolina at Chapel Hill, USA) "Alcohol Dysregulation of Midbrain Extended Amygdala Circuitry in Mice"
12:05 pm - 12:15 pm	Discussion
12:15 pm - 12:25 pm	Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Co-Morbid Use of Alcohol and Other Drugs Discussion Leader: Leandro Vendruscolo (National Institute on Drug Abuse, USA)
7:30 pm - 7:45 pm	Introduction by Discussion Leader
7:45 pm - 8:05 pm	Jibran Khokhar (University of Guelph, Canada) "Interactions between Alcohol and Other Drugs Across Development"
8:05 pm - 8:15 pm	Discussion
8:15 pm - 8:35 pm	Lori Knackstedt (University of Florida, USA) "Patterns and Consequences of Cocaine-Alcohol Polysubstance Use in Humans and Rodents"
8:35 pm - 8:45 pm	Discussion
8:45 pm - 8:55 pm	Short Talk Selected from Poster Abstracts
8:55 pm - 9:00 pm	Discussion
9:00 pm - 9:20 pm	Lara Ray (University of California, Los Angeles, USA) "Alcohol and Other Substance Co-Use in Clinical Samples"
9:20 pm - 9:30 pm	Discussion
Thursday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Business Meeting Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm	Motivational and Learned Determinants of Alcohol Self-Administration Discussion Leader: Dorit Ron (University of California, San Francisco, USA)
9:00 am - 9:15 am	Introduction by Discussion Leader
9:15 am - 9:35 am	David Lovinger (National Institute on Alcohol Abuse and Alcoholism, NIH, USA) "Basal Ganglia Roles in Alcohol Drinking and Impairment of Decision Making"
9:35 am - 9:45 am	Discussion
9:45 am - 10:05 am	Jocelyn Richard (University of Minnesota, USA) "Alcohol Impacts Neural Encoding and Molecular Mechanisms of Motivation"
10:05 am - 10:15 am	Discussion
10:15 am - 10:25 am	Short Talk Selected from Poster Abstracts
10:25 am - 10:30 am	Discussion
10:30 am - 11:00 am	Coffee Break
11:00 am - 11:20 am	Kristen Pleil (Weill Cornell Medicine, Cornell University, USA) "Estrogen Modulation of Limbic Synapses and Alcohol Drinking"
11:20 am - 11:30 am	Discussion
11:30 am - 11:40 am	Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am	Discussion
11:45 am - 12:05 pm	Segev Barak (Tel Aviv University, Israel) "Cellular and Molecular Mechanisms of Alcohol-Memory Reconsolidation and Relapse"
12:05 pm - 12:15 pm	Discussion
12:15 pm - 12:25 pm	Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Keynote Session: Alcohol Use Disorder Research: Co-Morbidities and Inequities Discussion Leader: Heather Richardson (University of Massachusetts Amherst, USA)
7:30 pm - 7:35 pm	Introduction by Discussion Leader
7:35 pm - 8:25 pm	Jaideep Bains (University of Calgary, Canada) "The Impacts of Stress: From Synapse to Society"
8:25 pm - 8:35 pm	Discussion
8:35 pm - 8:40 pm	Introduction by Discussion Leader
8:40 pm - 9:10 pm	Michael Taffe (UC San Diego, USA) "Cannabis and Alcohol Use Comorbidity in Animal Models"
9:10 pm - 9:20 pm	Discussion
9:20 pm - 9:30 pm	Closing Remarks
Friday
7:30 am - 8:30 am	Breakfast
9:00 am	Departure

Contributors

Research reported in this publication was supported by the National Institute On Alcohol Abuse And Alcoholism of the National Institutes of Health under Award Number R13AA028160. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Conference Links

Conference History Alcohol and the Nervous System (GRS) Contribute Financially to This Conference

Conference Fees

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Poster Information

Poster sessions are an integral part of the our conferences, and offer all conferees an opportunity to discuss their research.

Preparing your GRC poster

Diversity Funding

Financial assistance is available for qualified applicants through the GRC Carl Storm Underrepresented Minority Fellowship Program. This program provides a grant to underrepresented minority graduate students, postdocs, faculty and scientists to help fund their attendance at their first GRC meeting. Learn more.

Registration Fees

Conferee Single Room:

$1,505.00

Conferee Shared Room:

$1,240.00

Conferee Off-Site:

$860.00

Guest Single Room:

$1,315.00

Guest Shared Room:

$1,050.00

Guest Off-Site:

$670.00

Child 4-12 yrs Shared Room:

$525.00

Child 4-12 yrs Off-Site:

$335.00

Child Under 4 yrs Shared Room:

Free

Child Under 4 yrs Off-Site:

Free

Additional Fee Info

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