Conference Description
The 2019 Gordon Research Conference (GRC) on Alcohol-Induced End Organ Diseases "Inflammation and Cell Death: Mechanisms of Tissue Injury by Alcohol" will provide a unique forum to bring together a diverse range of young and established scientists who are studying alcohol-related organ damage. This newly approved Gordon Research Conference exclusively addresses alcohol-induced end organ disorders and will cover a broad range of studies at the molecular, cellular, systems and organismal level, with particular emphasis on multidisciplinary work and innovative approaches.
This GRC conference will 1) provide an international forum that promotes open discussion of cutting edge research at the forefront of alcohol-induced tissue injury, 2) foster the development of the next generation of investigators to study alcohol-induced organ damage, 3) promote interaction between young and senior investigators, 4) facilitate the exchange of ideas that will shape the future directions of the alcohol and tissue injury community and 5) introduce breakthrough techniques that facilitate the understanding of mechanisms driving alcohol-induced tissue injury. This GRC conference will significantly advance current understanding of the underlying mechanisms of end organ injury and stimulate development of effective therapeutic strategies for the diagnosis, prevention and treatment of alcohol-related disorders. Talks will address questions centered on the basic mechanisms that contribute to alcohol-induced organ damage across the entire lifespan and will include wide ranging experimental systems from microbiome to humans.
The format will provide ample time for formal and informal discussions and emphasize the presentation of unpublished data, thus ensuring that the newest and most exciting developments in the field are discussed. Poster presentations will take place on each day of the meeting, allowing for widespread participation of conference attendees at all career stages. Speakers will also be selected from submitted abstracts for "late-breaking topic" talks by young investigators. Participation by young investigators will be strongly encouraged.
The topics, speakers, and discussion leaders for the conference sessions are displayed below. The conference chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by November 24, 2018. Please check back for updates.
Keynote Session: Molecular and Cellular Mechanisms of Fibrosis
Discussion Leaders
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Jacquelyn Maher (University of California, San Francisco, USA)
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Vijay Shah (Mayo Clinic, USA)
Speakers
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Scott Friedman (Icahn School of Medicine at Mount Sinai, USA)
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Helen Hobbs (University of Texas Southwestern Medical Center, USA)
Protein and Organelle Homeostasis: Novel Mechanisms of Alcohol-Induced Organ Injury
Discussion Leaders
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Andras Orosz (National Institute on Alcohol Abuse and Alcoholism, NIH, USA)
Speakers
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Mark Czaja (Emory University, USA)
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Herbert Gaisano (University of Toronto, Canada)
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Mark McNiven (Mayo Clinic, USA)
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Hidekazu Tsukamoto (University of Southern California, USA)
Gut Derived Effectors
Discussion Leaders
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Ali Keshavarzian (Rush University Medical Center, USA)
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Bernd Schnabl (University of California, San Diego, USA)
Speakers
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J. Mark Brown (Lerner Research Institute, Cleveland Clinic, USA)
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Gabriel Perlemuter (INSERM, France)
Alcohol and Cell-Cell Communications: From Extracellular Vesicles to Cyto-, Chemo- and Adipokines
Discussion Leaders
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David Brigstock (Nationwide Children's Hospital, USA)
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Samir Ibrahim (Mayo Clinic, USA)
Speakers
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Natalia Nieto (University of Illinois at Chicago, USA)
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Gianfranco Alpini (Texas A&M University, USA)
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Won-Il Jeong (KAIST, South Korea)
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Steve Kliewer (University of Texas Southwestern Medical Center, USA)
Big Data and Bioinformatics: Emerging Insights from "Omics"
Discussion Leaders
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Suthat Liangpunsakul (Indiana University School of Medicine, USA)
Speakers
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Trina Norden-Krichmar (University of California, Irvine, USA)
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Mark Thursz (Imperial College London, United Kingdom)
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Heng Zhu (Johns Hopkins University, USA)
Genetic Factors, Post-Metabolic Signaling and Stress Pathways
Discussion Leaders
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Shelly Lu (Cedars-Sinai Medical Center, USA)
Speakers
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Bin Gao (National Institutes of Health, USA)
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Karen Reue (University of California, Los Angeles, USA)
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Elizabeth Speliotes (University of Michigan, USA)
Mitochondrial Dynamics, Dysfunction and Adaptation
Discussion Leaders
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John Lemasters (Medical University of South Carolina, USA)
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Shannon Bailey (University of Alabama at Birmingham, USA)
Speakers
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Meng Wang (Baylor College of Medicine, USA)
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Srinivasan Dasarathy (Cleveland Clinic, USA)
Translational and Clinical Approaches for Treatment of Alcohol-Induced Tissue Injury
Discussion Leaders
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Michele Pritchard (University of Kansas Medical Center, USA)
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Elizabeth Kovacs (University of Colorado Denver, USA)
Speakers
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Ramon Bataller (University of Pittsburgh, USA)
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Mariann Piano (University of Illinois at Chicago College of Nursing, USA)
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Fredrik Aberg (University of Helsinki, Finland)
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Gyongyi Szabo (University of Massachusetts Medical School, USA)
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Ellen Burnham (University of Colorado Denver, USA)
Systemic Effects of Alcohol: Cross-Talk Between Multiple Organs
Discussion Leaders
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Carol Casey (University of Nebraska, USA)
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Pranoti Mandrekar (University of Massachusetts Medical School, USA)
Speakers
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Patricia Molina (Louisiana State University, USA)
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Gavin Arteel (University of Louisville, USA)
