Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Alcohol: A Systemic Toxin
Discussion Leader: Hidekazu Tsukamoto (University of Southern California, United States)
7:40 pm - 8:15 pm
George Koob (National Institute on Alcohol Abuse and Alcoholism, NIH, United States)
"Closing the Treatment Gap: NIAAA Priorities"
8:15 pm - 8:30 pm
Discussion
8:30 pm - 9:05 pm
Scott Friedman MD (Icahn School of Medicine at Mount Sinai, United States)
"Alcohol: A Systemic Toxin and Systemic Problem"
9:05 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Alcohol and Neuro-Inflammation
Discussion Leader: Fulton Crews (UNC Bowles Center for Alcohol Studies, United States)
9:00 am - 9:20 am
Kimberly Nixon (The University of Texas at Austin, United States)
"Alcohol Primes Microglia: Alternative Roles and Phenotypes in Adolescent Models"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Joanne Weinberg (University of British Columbia, Vancouver, BC, Canada V6T1Z3, Canada)
"Prenatal Alcohol Exposure, Fetal Programming and Inflammation: Unmasking Developmental Origins of Adult Disease"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:50 am
Leon Coleman (UNC-CH Bowles Center for Alcohol Studies, United States)
"Involvement of Microglia in Alcohol-induced Neurodegeneration and Enhancement of Alzheimer’s Pathology"
10:50 am - 11:00 am
Discussion
11:00 am - 11:20 am
Paige Anton (University of Colorado Anschutz, United States)
"Defining a Role of Microglia in Ethanol- and Advanced Age-Related Neurodegeneration"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Rebecca McCullough (University of Colorado Anschutz Medical Campus, United States) and Leon Coleman (UNC-CH Bowles Center for Alcohol Studies, United States)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Alcohol, the GI Barrier and Gut-Peripheral Organ Axes
Discussion Leader: Bin Gao (National Institutes of Health, United States)
7:30 pm - 7:50 pm
Bernd Schnabl (University of California, San Diego, United States)
"The Role of The Intestinal Virome in Alcohol-Associated Liver Disease"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Gyongyi Szabo (Beth Israel Deaconess Medical Center / Harvard Medical School, United States)
"Gut-Organ Axes in Alcohol-Induced End Organ Disease"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Radhakrishna (RK) Rao (University of Tennessee Health Science Center, United States)
"Defining the Role of Calcium Channels in Alcohol-Associated Intestinal Barrier Dysfunction"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Irina Kirpich (University of Louisville, United States)
"The Role of Host and Microbial Epoxide Hydrolases in Alcohol-Associated Liver Injury and Inflammation"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Alcohol and Severe Injury
Discussion Leader: M. Katherine Jung (National Institute on Alcohol Abuse and Alcoholism, United States)
9:00 am - 9:20 am
Mashkoor Choudhry (Loyola University Chicago Health Sciences Division, United States)
"Mechanism(s) Underlying Intestine Immune Barrier Disruption Following Alcohol and Burn Injury"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Nicholas Gilpin (LSU Health Sciences Center New Orleans, United States)
"TBI & Alcohol Effects on Brain and Behavior"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:50 am
Borna Relja (Otto-von-Guericke University Magdeburg, Germany)
"Alcohol in Host Response to Trauma"
10:50 am - 11:00 am
Discussion
11:00 am - 11:20 am
Craig Coopersmith (Emory University, United States)
"CTLA-4 Checkpoint Inhibition in Alcohol and Sepsis"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Alcohol, Cancer Risk and Outcome
Discussion Leader: Robert Schwabe (Columbia University, United States)
7:30 pm - 7:50 pm
Jurgen Rehm (Centre for Addiction and Mental Health / University of Toronto, Canada)
"Public Alcohol Policies and Alcohol-related Cancers"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Mary Beth Terry (Columbia University, United States)
"Alcohol Intake and Breast Cancer - Latest Evidence and Remaining Gaps"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Benita McVicker (University of Nebraska Medical Center , United States)
"Alcohol and the Hepatic Microenvironment: A Recipe for Colorectal Liver Metastasis"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Raul Torres (University of Colorado School of Medicine, United States)
"Ethanol, Cancer and (Dys)regulation of Immune Surveillance"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Early Detection and Intervention for End Organ Damage
Discussion Leader: Vijay Shah (Mayo Clinic, United States)
9:00 am - 9:20 am
Lorenzo Leggio (National Institutes of Health, United States)
"Management and Treatment of AUD in patients with ALD"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Jay Luther (Massachusetts General Hospital, United States)
"Alcohol and Health Outcomes"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:50 am
Jessica Mellinger (University of Michigan, United States)
"Non-invasive Imaging of Alcohol-associated Liver Disease"
10:50 am - 11:00 am
Discussion
11:00 am - 11:20 am
Stephen Pandol (Cedars-Sinai Medical Center, United States)
"Treatments For Alcoholic Pancreatitis"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Alcohol and Comorbidities
Discussion Leader: Laura Nagy (Liver Disease Research Center, Cleveland Clinic Lerner Research Institute, United States)
7:30 pm - 7:50 pm
Pal Pacher (National Institute on Alcohol Abuse and Alcoholism, NIH, United States)
"Cardiovascular Effects of Alcohol in Aging"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Abigail Cannon (Loyola University Chicago Health Science Division, United States)
"Alcohol Potentiates Intestinal Pathologies Post Ulcerative Colitis"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Erin Lowery (University of Wisconsin-Madison, United States)
"Alcohol, Lung Disease and Lung Transplant"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Adam Kim (UConn Health, United States)
"Altered Innate Immune Responses in Peripheral Blood Mononuclear Cells in Heavy Drinkers with Obesity"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Alcohol, Inflamm-Aging and Senescence Across the Aging Spectrum
Discussion Leader: Andras Orosz (National Institute on Alcohol Abuse and Alcoholism, NIH, United States)
9:00 am - 9:20 am
Falk Lohoff (National Institues of Health / NIAAA, United States)
"Alcohol, Aging and Epigenetic Clocks"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Brian Kennedy (National University of Singapore, Singapore)
"Moderate Alcohol Intake, Metabolism and Aging"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:50 am
Heather Francis (Indiana University, United States)
"Mast Cell Regulation of Alcohol-Induced Liver Phenotypes"
10:50 am - 11:00 am
Discussion
11:00 am - 11:20 am
Ilhem Messaoudi (University of Kentucky, United States)
"Chronic Alcohol Drinking Disrupts Monocyte Differentiation in Bone Marrow Niche"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Informatic Advances in Alcohol-Induced End-Organ Diseases
Discussion Leader: Vasilis Vasiliou (Yale School of Public Health, United States)
7:30 pm - 7:50 pm
Christina Mair (University of Pittsburgh School of Public Health, United States)
"Using Spatial Analysis to Investigate Structural Determinants of Health"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Majid Afshar (University of Wisconsin - Madison, United States)
"Methods in Artificial Intelligence to Help Advance Identification and Treatment for Unhealthy Alcohol Use in Hospitalized Patients"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Takis Benos (University of Florida, United States)
"Computational Biology to Identify New Connections"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Kathleen McTigue (University of Pittsburgh, United States)
"PATH Network and Advance Medical Bioinformatics"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure