Conference Description
The Amyotrophic Lateral Sclerosis (ALS) and Related Motor Neuron Diseases GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.
The 2022 Gordon Conference brings together an exciting agenda of topics that highlights recent scientific and clinical advances for ALS, ALS/FTD and related motor neuron diseases. The conference will feature a wide range of topics that focus on disease basic biology and mechanism, such as TDP-43 based neurodegeneration and cryptic splicing, neuroinflammation and vascular biology, axonal biology, as well as genetic modifiers of motor neuron disease. In addition to the mechanistic science, there will be an emphasis on translational science, involving preclinical animal models, therapeutic strategies, biomarkers, and the review of recent clinical trials.
The topics, speakers, and discussion leaders for the conference sessions are displayed below. The conference chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by March 4, 2023. Please check back for updates.
Translational Science and Therapeutic Landscape
Discussion Leaders
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Charlotte Sumner (Johns Hopkins University School of Medicine, United States)
Speakers
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John Day (Stanford University, United States)
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Don Cleveland (Ludwig Institute for Cancer Research, United States)
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Steven Gray (University of Texas Southwestern Medical Center, United States)
TDP-43 and Neurodegeneration: Loss of Function, Cryptic Splicing, and Therapeutics
Discussion Leaders
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Emanuele Buratti (ICGEB, Italy)
Speakers
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Pietro Fratta (University College London, United Kingdom)
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Clotilde Lagier-Tourenne (Harvard Medical School / Massachusetts General Hospital, United States)
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Magdalini Polymenidou (University of Zurich, Switzerland)
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Yuna Ayala (Saint Louis University, United States)
Emerging Genetic and Mechanistic Modifiers of ALS and FTD
Discussion Leaders
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Rosa Rademakers (University of Antwerp & Flemish Institute for Biotechnology (VIB), Belgium)
Speakers
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Leonard Petrucelli (Mayo Clinic College of Medicine and Science, United States)
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Benjamin Ryskeldi-Falcon (MRC Laboratory of Molecular Biology, United Kingdom)
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Dorothee Dormann (Johannes Gutenberg University (JGU) Mainz, Germany)
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Sami Barmada (University of Michigan, United States)
Axonal and Synapse Biology; Degeneration in Motor Neuron Diseases
Discussion Leaders
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Jeroen Pasterkamp (University Medical Center Utrecht, The Netherlands)
Speakers
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Alison Twelvetrees (The University of Sheffield, United Kingdom)
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Robert Burgess (The Jackson Laboratory, United States)
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Eran Perlson (Tel Aviv University, Israel)
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Sandrine Da Cruz (VIB- KU Leuven Center for Brain and Disease Research, Belgium)
Neuroinflammation and Vascular Biology in ALS and FTD
Discussion Leaders
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Severine BOILLEE (ICM - INSERM - Sorbonne University, France)
Speakers
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Eric Huang (University of California, San Francisco, United States)
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Renzo Mancuso (VIB-Center for Molecular Neurology and University of Antwerp, Belgium)
Astrocyte Biology in ALS and FTD
Discussion Leaders
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Jeffrey Rothstein (Johns Hopkins University, United States)
Speakers
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Brigitte Van Zundert (Andres Bello University, Chile)
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Kristine Freude (University Copenhagen, Denmark)
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Shane Liddelow (NYU Grossman School of Medicine, United States)
Translational Biomarkers
Discussion Leaders
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Lucie Bruijn (Novartis, Switzerland)
Speakers
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David Owen (Imperial College London, United Kingdom)
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Sanjay Kalra (University of Alberta, Canada)
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ANDREA MALASPINA (QS MND CENTRE, INSTITUTE OF NEUROLOGY, UCL, United Kingdom)
Translational Science in ALS and FTD
Discussion Leaders
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David Taylor (ALS Society of Canada, Canada)
Speakers
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Timothy Miller (Washington University in St. Louis, United States)
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Neil Shneider (Columbia University, United States)
Late-Breaking Topics
Discussion Leaders
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Don Cleveland (Ludwig Institute for Cancer Research, United States)
Speakers
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Michael Ward (National Institutes of Health, United States)
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Chris Henderson (Biogen, United States)
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Christopher Pearson (The Hospital for Sick Children, Canada)
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Aaron Gitler (Stanford University, United States)
The GRC Power Hourâ„¢
Organizers
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Aarti Sharma (Regeneron, United States)