The modern world is filled with macroscopic machines that perform work that we either find demanding or function in places or on length scales in which we cannot act. To date however, we have yet to develop a functional nanotechnology that operates on the scale of molecules or assemblies of molecules. Nature provides the ultimate inspiration of what might be achieved if we overcome this final frontier to fully harness the dynamic properties of molecular systems; sliding actin-myosin fibers and rotating ATP synthase paint a picture of a mechanized nanotechnology where many small motors impact our macroscopic world.

Scientists from a range of disciplines are working to understand, design, and create the next generation of switches and motors to mechanize our world from the bottom up. Organic chemists create novel molecules performing reversible switching. Theoretical scientists provide the understanding that underpins predictive designs. Soft and hard matter scientists and engineers integrate molecular switches into higher-order architectures, ultimately giving rise to macroscopic motion. Bioengineers and physicists create kinesin-like walkers to test understanding of small motors. Biologist apply switches to control the behavior of living systems and develop new therapeutic techniques. The aim of this GRC is to bring together and provide a forum for this multidisciplinary group of researchers where they can present ideas, experimental examples, and physical descriptions of artificial switches and motors to achieve the potential of a functional artificial molecular nanotechnology. The unique meeting format of a GRC, with ample time for discussion and an ethos of encouraging the open exchange of new data and ideas, will enable us to accelerate progress and push frontiers and develop new applications with Artificial Molecular Switches and Motors.