Molecular Mechanisms, Genomic Modifiers and Emerging Therapies

The Atherosclerosis GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

We will: 1) Highlight novel techniques being used to investigate atherosclerosis including high dimensional profiling and spatial organization of vascular and immune cells in the vessel wall, as well as systems biology and machine learning approaches that analyze the atherosclerotic plaque as a whole entity, rather than studying individual cell types as has been done in the past; 2) Discuss new molecular pathways regulating vascular and immune cell function, mechanisms of atherosclerosis regression, immunometabolism, clonal hematopoiesis and genetics of atherosclerosis; 3) Focus on complications of atherosclerosis such as diabetes, myocardial infarction, stroke and neurodegeneration. The program will also incorporate short talks and posters from submitted abstracts to capture the latest results and provide ample presentation opportunities for trainees and students.