1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Lipid-Binding Proteins in Selective and Non-Selective Types of Autophagy
Anita Kumar (Brown University, United States) and Satya Surabhi (Albert Einstein College of Medicine, United States)
3:45 pm - 4:20 pm
Anne Simonsen (University of Oslo, Norway) "Lipid-Binding Proteins in Selective and Non-Selective Types of Autophagy"
4:20 pm - 4:30 pm
4:30 pm - 6:00 pm
6:00 pm - 7:00 pm
7:30 pm - 9:30 pm
Mechanisms of Bulk and Selective Autophagy
Prince Amponsah (Technische Universität Kaiserslautern, Germany) and Smriti Parashar (UC San Diego, United States)
7:30 pm - 7:45 pm
Liv Jensen (University of California, Berkeley, United States) "Membrane Curvature Sensing by the Autophagy Initiation Machinery"
7:45 pm - 7:50 pm
7:50 pm - 8:05 pm
Colten McEwan (Brigham Young University, United States) "ATG9A-Mediated Turnover of p62 Condensates Requires Ubiquitin and Occurs Independently of the LC3-Lipidation Machinery"
8:05 pm - 8:10 pm
8:10 pm - 8:25 pm
Camille Lacarriere-Keita (Université de Sherbrooke, Canada) "Sbf and Rab21 Play a New Role in Adult Drosophila Intestinal Cell Differentiation, Most Likely Through Their Regulatory Functions on Autophagy"
8:25 pm - 8:30 pm
8:30 pm - 8:45 pm
Rukmini Mukherjee (Max Planck Institute of Biophysics/Goethe university, Germany) "
De Novo Regeneration of Lysosomes from Damaged Membranes During Lysophagy"
8:45 pm - 8:50 pm
8:50 pm - 9:05 pm
Ankit Shroff (Georgia State University, United States) "Yeast eIF2A is a Novel Regulator of Lipophagy"
9:05 pm - 9:10 pm
9:10 pm - 9:25 pm
Andrew Leidal (University of California, San Francsico, United States) "Autophagy Cargo Receptors are Secreted via Extracellular Vesicles and Particles in Response to Endolysosomal Inhibition or Impaired Autophagosome Maturation"
9:25 pm - 9:30 pm
7:30 am - 8:30 am
9:00 am - 11:00 am
Mechanisms of Autophagy Dysfunction and Targeting in Disease
Rukmini Mukherjee (Max Planck Institute of Biophysics/Goethe university, Germany), Dingxi Zhou (Kennedy Institute of Rheumatology, University of Oxford, United Kingdom) and Ee Phie Tan (The Scripps Research Institute, United States)
9:00 am - 9:15 am
Julian Carosi (South Australian Health and Medical Research Institute, Australia) "Retromer Regulates the Lysosomal Clearance of Tau"
9:15 am - 9:20 am
9:20 am - 9:35 am
Eunju Im (Nathan S. Kline Institute / NYU Grossman School of Medicine, United States) "Phosphorylated APP via its CTF Directly Disrupts v-ATPase and Lysosomal Acidification in Down Syndrome-A Cause of Early Onset Alzheimer’s Disease"
9:35 am - 9:40 am
9:40 am - 9:55 am
Houfu Leng (University of Oxford, United Kingdom) "Improving Bone Health via Modulation of Glycosphingolipid Metabolism and Autophagy"
9:55 am - 10:00 am
10:00 am - 10:15 am
Dilru Silva (Huntsman Cancer Institute, University of Utah, United States) "Lysosome Inhibition Overcomes Resistance to CDK4/6 Inhibition in Pancreatic Cancer"
10:15 am - 10:20 am
10:20 am - 10:35 am
Ryan Hippman (University of Illinois at Chicago, Department of Chemistry, United States) "Development of Protein-Protein Interaction Inhibitors to Selectively Inhibit Autophagy"
10:35 am - 10:40 am
10:40 am - 10:55 am
Elizabeth Gallagher (University of Pennslyvania, United States) "The Selective Autophagy Receptor p62 Regulates Lysophagy in HeLa Cells and in Neurons"
10:55 am - 11:00 am
11:00 am - 12:30 pm
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
1:30 pm - 2:30 pm
Mentorship Component: Life After a PhD
Patricia Boya (Centro de Investigaciones Biológicas, CSIC, Spain)
1:30 pm - 2:30 pm
Life After a PhD
Jayanta Debnath (University of California, San Francisco, United States)
Jeff Willy (Vertex Pharmaceuticals , United States)
Anne Simonsen (University of Oslo, Norway)
2:30 pm - 3:00 pm
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