Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Envelope Macromolecular Machines
7:40 pm - 8:00 pm
"Linking Lipoprotein Export to Outer Membrane Vesicle Biogenesis in Bacteroides "
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
"Clostridioides Difficile Cell Separation Relies on Two Parallel Peptidoglycan Degradation Pathways"
8:20 pm - 8:25 pm
Discussion
8:25 pm - 8:35 pm
"A Conserved Domain of Unknown Function Protein links Envelope Integrity to Lipid A Modification in Brucella "
8:35 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
"Investigating Micromembrane Protein Assembly in Corynebacterium Glutamicum"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:15 pm
"Antibiotic Perturbation of the Septal Peptidoglycan Synthesis Machinery in Vivo"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:20 am
"How a Cell Envelope Stress-Response Pathway Revealed a Treasure Trove of New Cell Envelope Biology"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Bacillus Subtilis LiaH Protects from Cell Wall Precursor-Targeting Antimicrobials"
9:40 am - 9:45 am
Discussion
9:45 am - 10:05 am
"Structure-Function Analysis of Inter-Membrane Phospholipid Transporters"
10:05 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Trafficking of lipids in the Brucella Abortus Pathogen"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"c-di-GMP Regulates Cell Surface Proteins to Promote Intracellular Replication and Survival of Rickettsia parkeri "
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"The Two Tether Divisome System Ensures Timely Bacterial Cell Division"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Mechanistic Insights into the Divisome-Elongasome Transition in Mycobacteriales "
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Discovery of a Membrane Protein Complex that Coordinates Cell Envelope Assembly in Mycobacteria"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Transport through the Cell Envelope
7:30 pm - 7:50 pm
"Using Structural Biology to Understand The Surface-based Toolkit Of The Bacterial Predator Bdellovibrio"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Mutual Adaption of an Ixotrophic Bacterial Predator and its Prey in the Ocean"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Lipoprotein Synthesis in Bacteroides "
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Small Phage Proteins Remodel Cell-Surface Polysaccharides"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Contact-Dependent Delivery of Protein Effectors into Prokaryotic and Eukaryotic Target Cells"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Sensing and Balancing Cell Envelope Biogenesis
9:00 am - 9:20 am
"Investigating the Function of Essential Lipid Phosphates in Gram-Positive Bacteria"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Flagellar Toxicity: Flagellar Synthesis is Lethal in Bacillus Subtilis in the Absence of PBP1"
9:40 am - 9:45 am
Discussion
9:45 am - 10:05 am
"Molecular Architecture of Streptococcus Pneumoniae Peptidoglycan Using Correlative Atomic Force Microscopy"
10:05 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Crosstalk Between Surface Glycopolymers and Cell Wall Synthases Ensures Envelope Integrity and Virulence in an Important Human Pathogen"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"The Bam Complex: Why BamA Doesn’t Work Alone"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"A Family Affair: Distinct Stabilization Roles for the YfgH/SlyB Family in the E. coli Outer Membrane"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Molecular Mechanisms That Regulate Homeostatic Control of Phospholipids and Lipopolysaccharides"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"An Expanded LptD Complex Mediates Surface Lipoprotein Export in the Bacteroidota"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Building and Remodeling the Bacterial Envelope
7:30 pm - 7:50 pm
"Conformational Dynamics of SPFH Membrane Microdomains Regulate Bacterial Proteostasis and Stress Recovery"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"A Proteolytic Circuit Integrates Peptidoglycan Remodeling with Outer Membrane Homeostasis in Gram-Negative Bacteria"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Organising the E. coli Outer Membrane"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Outer Membrane–Peptidoglycan Anchoring in Pseudomonas aeruginosa "
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Balancing the Layers of the Gram-Negative Cell Envelope"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Maintenance of the Cell Envelope
9:00 am - 9:20 am
"Defining a Regulatory Framework for Polar Growth in Agrobacterium Tumefaciens "
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Membrane-Dependent Regulation of PlsX Controls Phospholipid Synthesis in B. Subtilis"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Characterization of SalTI, a New Regulatory System of Cell Death in S. aureus"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"A Shared Interbacterial Membrane Underlies Mycobacterial Cording"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Functional Characterisation of a Conserved Cell Division Factor in Actinomycetota"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"A Role for Antibiotic Biosynthesis in the Function of the Bacterial Cell Envelope"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Structural Insights into Clostridioides Difficile Spore Germination"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Integrating Genome-Scale AI-Based Structural Approaches and High-Throughput CRISPRi Phenotyping to Understand Mycobacterial Envelope Assembly"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:50 pm
"Surveillance and Repair of the Gram-Negative Bacterial Envelope"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"L,D-Transpeptidases are Essential in C. difficile "
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Ins and outs Across the Mycobacterial Cell Envelope"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"A New Broadly Conserved Gram-Positive Component of the Rod Complex"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Disarm and Disengage: Understanding Aurodox A Type III Secretion System inhibitor from Streptomyces "
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
9:00 am - 9:10 am
"Mechanistic Insights from Reconstitution of CDI Toxin Delivery in Proteoliposomes"
9:10 am - 9:15 am
Discussion
9:15 am - 9:35 am
"A Balancing Act: Regulation of Cell Envelope Biosynthesis in Pseudomonas Aeruginosa "
9:35 am - 9:45 am
Discussion
9:45 am - 10:15 am
Coffee Break
10:15 am - 10:35 am
"Regulating Membrane Synthesis in Bacillus Subtilis "
10:35 am - 10:45 am
Discussion
10:45 am - 10:55 am
"A Novel Post-Translational Modification to Fimbriae Drives Pathogenicity in Klebsiella pneumoniae "
10:55 am - 11:00 am
Discussion
11:00 am - 11:10 am
"Genetic Dissection of Type IV Pili Reveals Mechanisms of Saccharibacteria Episymbiosis and Immune Modulation"
11:10 am - 11:15 am
Discussion
11:15 am - 11:25 am
"Exploring the S-Layer Assembly Dynamics During Bacillus Anthracis Growth"
11:25 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Closing the Divide: Membrane Dynamics During Cytokinesis"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Insights into how Clostridioides Difficile Spores Sense Bile Acid Germinant Signals"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:50 pm
"A Quantitative Methodology for Distinguishing Growth-Competent and Lethal Mutants in Genome-Scale Transposon Mutagenesis Experiments"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"GlmU's Uridyltransferase Activity is not Essential for Making Peptidoglycan in Staphylococcus Aureus "
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Lysophospholipid Signaling Impacts Membrane Homeostasis"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Environmentally Mediated Changes in PBP Activity Support a Modular Model for Cell Wall Synthesis in Two Enterobacteriaceae"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Evolutionary Shift from Lateral Wall Insertion to Tip Growth in a Firmicute"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure