|Sunday, August 5th|
|2:00pm-11:00pm|| Arrival and registration|
|7:30-9:30pm ||Barrier assembly and degradation|
|Session Chair: Thea Mauro, University of California, San Francisco|
|Gloria Sando, University of Iowa|
"Caveolins: Lipid Transport and Organizing Proteins with Diverse Functions - Do
They Play a Role in the Epidermal Barrier?"
|Joachim Fluhr, University of California, San Francisco|
"Generation of Free Fatty Acids from Phospholipids Regulates Stratum Corneum Acidification and Integrity in Adults and Neonates"
|Allan Watkinson, Unilever Research UK|
"SCCE in the Stratum Corneum: A Unique Environment for a Proteolytic Enzyme"
|Monday, August 6th|
|9:00am -12:30pm ||Transdermal drug delivery|
|Session Chair - Martha Tate, Kimberly-Clark|
|Samir Mitragotri , University of California, Santa Barbara|
"Mechanisms of Low-Frequency Sonophoresis"
|Loan Honeywell-Nguyen, Leiden-Amsterdam Ctr for Drug Rsch|
"Elastic Vesicles: Drug Transport and Mechanisms of Action"
|Apostolos Doukas, Wellman Laboratories of Photomedicine, Boston|
"Permeabilization of the Stratum Corneum with Pressure Waves: Implications for Transdermal Drug Delivery"
|Jurgen Lademann, Humboldt University Berlin
"Open vs. Closed Follicles"
|4:00-5:00pm ||Session I posters mounted
|5:00-6:00pm|| First opportunity to view Session I posters|
|Session Chair - Chris Cullander, University of California, San Francisco|
|Gregory Glenn, Walter Reed Army Institute of Research|
"Transcutaneous Immunization: Using Adjuvants on the Skin to Induce Systemic Immune Responses"
|William Costerton, Montana State University|
"The Microbial Ecology of the Intact and Disturbed Human Skin"
|John A. Mikszta, BD Technologies, Research Triangle Park|
"Microfabricated Arrays Effectively Disrupt Skin Barrier Function and Facilitate Topical Gene Transfer and Genetic Immunization."
|9:30-10:30pm ||Session I poster presenters stand by their posters|
|Tuesday, August 7th|
|9:00am-12:30pm ||Cell and molecular biology of barrier function|
|Session Chair - Isabelle Castiel, L'Oreal|
|Carolyn Byrne, University of Manchester, UK|
"Formation of the Fetal Barrier"
|Arto Maatta, University of Durham, UK|
"Role of Plakin Family of Cytoskeletal Linker Proteins in Cornified Envelope Assembly"
|Marty Visscher, Skin Science Institute, Cincinnati|
"Vernix Biology and Barrier Development"
|Julia Segre, National Human Genome Research Institute/NIH|
"A Genomics Approach to KLF4's Role in Transcriptional Control of Epidermal Barrier Establishment"
|5:00-6:00pm ||Second opportunity to view posters in Session I|
|7:30-9:30pm ||Physical properties of skin|
|Session Chair - Joke Bouwstra, Leiden-Amsterdam Ctr for Drug Rsch|
|Peter Caspers, Erasmus University, Rotterdam|
"In Vivo Depth Profiling of Water and Other Skin Constituents by Raman Microspectroscopy"
|David Moore, Unilever US|
"Lipids: Headgroup Hydrogen Bonding and Chain Behavior in Phytosphingosine and Sphingosine Ceramides"
|Alexandre Samouilov, Johns Hopkins University School of Medicine|
"Application of Electron Paramagnetic Resonance Imaging Technique for Measurement of Skin Permeability and Redox state"
|9:30-10:30pm ||Session I poster presenters stand by posters|
|10:30pm ||Session I posters come down|
|Wednesday, August 8th|
|9:00am-12:30pm ||Skin modeling|
|Session Chair - William Van Osdol, ALZA Corporation|
|Jerry Kasting, University of Cincinnati|
"Evaluation of Stratum Corneum Heterogeneity by a Combination of Membrane Transport and Uptake/Desorption Techniques"
|Lars Norlén, GAP Biomédical, Geneva|
"Is the Skin Barrier a Single and Coherent Gel Phase Formed Through Unfolding of a Three-Dimensional Continuous Cubic-Like Membrane Structure with Symmetry?"
|Annette Bunge, Colorado School of Mines|
"Does Surface Distribution of Solid Chemical Affect Dermal Absorption?"
|James Weaver, MIT|
"Avoiding Math While Solving Increasingly Realistic Models for Molecular Transport Through the Stratum Corneum"
|4:00-5:00pm ||Session II posters mounted
|5:00-6:00pm ||First opportunity to view Session II posters|
|7:30-9:30pm||Debate and Business Meeting|
|Debate topic: "Skin Reservoir Function is an Artifact"|
|Moderator: Ken Walters, An-eX, Cardiff|
|Pro: Jerry Kasting, University of Cincinnati|
|Con: Mike Roberts, University of Queensland|
|9:30-10:30pm|| Session II poster presenters stand by posters
|Thursday, August 9th|
|9:00am-12:30pm ||Skin imaging|
|Session Chair - Gopi Menon, Avon Products, Inc.|
|Roger Wepf, Beiersdorf AG|
"Re-viewing the Structure of the Stratum Corneum: the Corneocytes Embrace Each Other"
|Nik Kollias, Johnson & Johnson Consumer Products|
"Macro-and-Micro Imaging of-and-through Stratum Corneum"
|Milind Rajadhyaksha, Massachusetts General Hospital|
"Confocal Imaging of Human Stratum Corneum In Vivo: Optimum Methods and Applications"
|Martin Behne, Veterans Administration Medical Center, San Francisco|
"The Stratum Corneum pH Gradient: A New Look at the "Acid Mantle""
|5:00-6:00pm ||Second opportunity to view posters in Session II|
|7:30-9:30pm ||Hot Topics|
|Session Chair - Maria Ponec, Leiden University Medical Center|
|Gabriele Vielhaber, Haarmann & Reimer GmbH, Holzminden|
"Immunocytochemical Localization of (Glucosyl)ceramides in Human Epidermis - A Role for Epidermal Ceramides Beyond Providing the Barriers Mortar?"
|Olga Lopez Serrano, Consejo Superior de Investigaciones Cientificas, Barcelona|
"Cornified envelope: Could Fatty Acids be Covalently Linked to Serine Residues?"
|Melanie Chopart, L'Oreal, Paris|
"Free and Bound Human Ceramides. Normal and Dry skin."
|(speaker information will be available at the Conference) |
|9:30-10:30pm||Session II poster presenters stand by posters|
|10:30pm||Session II posters come down|