Conference Description
The 2019 Conference on Cancer Genetics and Epigenetics will focus on newly emerging aspects of the field including the genetic heterogeneity of cancer, the “long tail” of less frequent cancer mutations and the importance of intratumoral heterogeneity as assayed by single cell technologies. The importance of the non-coding genome in cancer will be highlighted as well as the rapidly evolving field of RNA epigenetics. Sessions on the lessons learned from genome wide surveys of cancer susceptibility as assayed by CRISPR screens and descriptions of cancer epigenomes will be complemented by talks on basic mechanism of gene regulation relevant to cancer and how genetically and epigenetically targeted therapies can be applied to specific tumor types. It has become increasingly apparent that the organization of the genome across temporal and spatial domains plays a large role in the control of cancer gene expression patterns and tumor biology and a session on the “4-D Nucleome” and cancer is planned. The large amounts of data generated by modern cancer genetic and epigenetic experiments require new modes of computational and systems analysis which will be discussed in sessions. This meeting should appeal to a wide range of cancer researchers and molecular biologists seeking to apply their work to cancer. In addition to an outstanding set of invited speakers there will be several interactive poster sessions, one minute "poster preview" talks and several talks selected for platform presentation from the submitted abstracts.
The topics, speakers, and discussion leaders for the conference sessions are displayed below. The conference chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by December 7, 2018. Please check back for updates.
Keynote Session: Translating Cancer Genetics and Epigenetics to Therapy
Discussion Leaders
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Saverio Minucci (European Institute of Oncology, Italy)
Speakers
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Ricky Johnstone (Peter MacCallum Cancer Centre, Australia)
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Anjana Rao (La Jolla Insitute for Allergy and Immunology, USA)
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Elaine Mardis (Institute for Genomic Medicine, Nationwide Children's Hospital, USA)
Non-Coding RNA and Cancer
Discussion Leaders
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Rolf Renne (University of Florida, USA)
Speakers
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Howard Chang (Stanford University, USA)
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Lynne Maquat (School of Medicine and Dentistry, University of Rochester Medical Center, USA)
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Marcus Peter (Northwestern University, USA)
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Lin He (Univeristy of California, Berkeley, USA)
The Cancer Epitranscriptome
Discussion Leaders
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Sandeep Dave (Duke University, USA)
Speakers
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Chuan He (University of Chicago, USA)
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Tony Kouzarides (University of Cambridge, United Kingdom)
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Francois Fuks (Free University of Brussels, Belgium)
The Genetics and Epigenetics of Tumor Heterogeneity
Discussion Leaders
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Giovanni Tonon (San Raffaele Scientific Institute, Italy)
Speakers
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Li Ding (Washington University in St. Louis, USA)
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Duncan Odom (University of Cambridge, United Kingdom)
Functional Studies of the Cancer Genome and Epigenome
Discussion Leaders
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Ashby Morrison (Stanford University, USA)
Speakers
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Cigall Kadoch (Dana-Farber Cancer Institute, USA)
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Ross Levine (Memorial Sloan Kettering Cancer Center, USA)
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Christopher Vakoc (Cold Spring Harbor Laboratory, USA)
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Luke Gilbert (University of California, San Francisco, USA)
The Genetics and Epigenetics of Immuno-Oncology
Discussion Leaders
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Kate Chiappinelli (George Washington University, USA)
Speakers
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Ari Melnick (Weill Cornell Medicine, USA)
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Stephen Baylin (Johns Hopkins University, USA)
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Zeming Zhang (Peking University, China)
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Peter Jones (Van Andel Institute, USA)
Genome-Wide Studies of Epigenetics and Cancer
Discussion Leaders
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Jane Skok (New York University, USA)
Speakers
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Maria Figueroa (University of Miami, USA)
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Mathieu Lupien (Princess Margaret Cancer Centre, Canada)
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Toshikazu Ushijima (National Cancer Center Research Institute, Japan)
Computational Approaches to Cancer Genetics and Epigenetics
Discussion Leaders
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Jindan Yu (Northwestern University, USA)
Speakers
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Sohrab Shah (University of British Columbia, Canada)
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Kai Tan (Children's Hospital of Philadelphia, USA)
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Christina Leslie (Memorial Sloan Kettering Cancer Center, USA)
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Hui Shen (Van Andel Institute, USA)
Cancer and the 4-D Nucleome
Discussion Leaders
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Albert Jeltsch (University of Stuttgart, Germany)
Speakers
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Peter Fraser (Florida State University, USA)
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Ana Pombo (Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Germany)
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Margaret Goodell (Baylor College of Medicine, USA)
