Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: CAZymes for Environmental Sustainability and Human Health
Discussion Leader: Emma Master (University of Toronto, Canada)
7:40 pm - 7:55 pm
Introduction by Discussion Leader
7:55 pm - 8:25 pm
Breeanna Urbanowicz (University of Georgia, United States)
"Development of Modular Platforms for Cell Free Biosynthesis of Complex Polysaccharides"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 9:05 pm
Matthew Redinbo (University of North Carolina at Chapel Hill, United States)
"Gut Microbial Glycoside Hydrolases"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Molecular Mechanisms of Complex Carbohydrate Degradation
Discussion Leader: Bernd Nidetzky (Graz University of Technology, Austria)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
Zarah Forsberg (Norwegian University of Life Sciences (NMBU), Norway)
"Recent Insights into LPMO Structure, Function and Operational Stability"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
Late-Breaking Topic
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
Elisabeth Lowe (Newcastle University, United Kingdom)
"Discovering Arabinofuranosidases for Deconstruction of Mycobacterial D-Arabinan"
11:15 am - 11:25 am
Discussion
11:25 am - 11:50 am
Roland Ludwig (University of Natural Resources and Life Sciences, Austria)
"Measurement and Visualization of LPMO Activity on Natural Substrates"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
Short Talk Selected from Poster Abstracts
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizer: Paul Walton (University of York, United Kingdom)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Visualizing CAZyme-Substrate Interactions
Discussion Leader: Steve Decker (NREL, United States)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
Shishir Chundawat (Rutgers, The State University of New Jersey, United States)
"Mr. Cell, Tear Down This Wall: Visualizing Cellulose Biosynthesis, Assembly, & Degradation"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
William Hancock (Pennsylvania State University, United States)
"Pausing, Processivity, and Product Inhibition: Single-Molecule Imaging of Cel7A on Cellulose"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:00 pm
Short Talk Selected from Poster Abstracts
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:15 pm
Short Talk Selected from Poster Abstracts
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Bacterial CAZymes Targeting Human Host Glycans
Discussion Leader: Mario Murakami (Brazilian Biorenewables National Laboratory / National Center for Research in Energy and Materials, Brazil)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
Alisdair Boraston (University of Victoria, Canada)
"Processing of Glycoproteins by Host-Adapted Bacteria"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
Marcelo Guerin (Biobizkaia Health Research Institute, Spain)
"Mechanism of Antibody-Specific Deglycosylation and Immune Evasion by Streptococcal IgG-Specific Endoglycosidases"
10:10 am - 10:20 am
Discussion
10:20 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
Tracey Gloster (University of St Andrews, United Kingdom)
"Structural and Mechanistic Insights Into Sulfatases"
11:20 am - 11:30 am
Discussion
11:30 am - 11:45 am
Short Talk Selected from Poster Abstracts
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
Short Talk Selected from Poster Abstracts
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
CAZymes Prospecting and Discovery
Discussion Leader: Michelle O'Malley (University of California, Santa Barbara, United States)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
Yanbin Yin (University of Nebraska - Lincoln, United States)
"From dbCAN to dpCAN: Application of Machine Learning for new CAZyme Discovery"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
Robert Gruninger (Agriculture and Agri-food Canada, Canada)
"Characterizing the microbial communities and enzymes responsible for carbohydrate metabolism in the rumen"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
Lauren McKee (KTH, Royal Institute of Technology, Sweden)
"Family 92 Carbohydrate-Binding Modules: Structure, Function, and Impacts on Enzyme Activity."
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Plant Cell Wall Construction and Deconstruction
Discussion Leader: Debra Mohnen (University of Georgia, United States)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
Charles Anderson (Penn State University, United States)
"Navigating Molecular and Structural Complexity in Cell Wall Modification and Degradation"
9:35 am - 9:45 am
Discussion
9:45 am - 10:00 am
Short Talk Selected from Poster Abstracts
10:00 am - 10:05 am
Discussion
10:05 am - 10:20 am
Short Talk Selected from Poster Abstracts
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
Kevin Solomon (University of Delaware, United States)
"Anaerobic Fungal CAZYme Adaptations to Lignin Composition"
11:20 am - 11:30 am
Discussion
11:30 am - 11:45 am
Short Talk Selected from Poster Abstracts
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
General Discussion
12:05 pm - 12:25 pm
Late-Breaking Topic
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
CAZymes for Novel Glycan Synthesis
Discussion Leader: Kiyohiko Igarashi (The University of Tokyo)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
Sabine Flitsch (University of Manchester, United Kingdom)
"Applications of Carbohydrate-Active Enzymes in Bio-conjugate Synthesis"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
Carme Rovira (Universitat de Barcelona, Spain)
"Simulation of Glycosyltransferase Catalytic Mechanisms"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Short Talk Selected from Poster Abstracts
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
CAZyme-Based Biotherapeutic Design
Discussion Leaders: Romina Rodríguez Sanoja (UNAM, Instituto de Investigaciones Biomédicas, Mexico) and Romina Rodríguez Sanoja (UNAM, Instituto de Investigaciones Biomédicas, Mexico)
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
Darrell Cockburn (Pennsylvania State University, United States)
"The Different Paths to Resistant Starch Degradation and Their Impact on Human Health"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
Isaac Cann (University of Illinois at Urbana-Champaign, United States)
"Development of a Polysaccharide Sensing and Degradation Signature (PSDS) in the Bacteroidota to Manipulate Human Health and Nutrition"
10:10 am - 10:20 am
Discussion
10:20 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
Craig Vander Kooi (University of Florida, United States)
"Development of Glycogen Active Enzymes as Therapeutics in the Central Nervous System"
11:20 am - 11:30 am
Discussion
11:30 am - 11:45 am
Short Talk Selected from Poster Abstracts
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
Short Talk Selected from Poster Abstracts
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
CAZyme-Assisted Biomaterial Production
Discussion Leader: Anne S Meyer (Technical University of Denmark, Denmark)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
Bryan Berger (University of Virginia, United States)
"Sequence, Structure and Specificity in Hydrophobin Interactions During Liganocellulosic Biomass Deconstruction"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Short Talk Selected from Poster Abstracts
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:55 pm
Olanrewaju Raji (University of Toronto, Canada)
"LPMOs Alone and in Biocatalytic Cascade for Cellulose Fiber Surface Functionalization"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:20 pm
General Discussion
9:20 pm - 9:30 pm
Closing Remarks
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure