Sunday
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2:00 pm - 8:00 pm |
Arrival and Check-in
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6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 7:40 pm |
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
|
7:40 pm - 9:30 pm |
Structures and Glycomics
Discussion Leader: Xuefei Huang (Michigan State University, USA)
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7:40 pm - 8:05 pm |
Daron Freedberg (Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, USA)
"NMR Studies of the 3D Structures of Sialic Acid Containing Oligo- and Polysaccharides"
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8:05 pm - 8:15 pm |
Discussion
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8:15 pm - 8:40 pm |
Christina Woo (Harvard University, USA)
"Mapping and Manipulating the Glycoproteome"
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8:40 pm - 8:50 pm |
Discussion
|
8:50 pm - 9:15 pm |
Sabine Flitsch (University of Manchester, United Kingdom)
"Application of Bacterial CAZY Enzymes for the Synthesis of Glycoconjugates"
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9:15 pm - 9:25 pm |
Discussion
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9:25 pm - 9:30 pm |
General Discussion
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Monday
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7:30 am - 8:30 am |
Breakfast
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9:00 am - 12:30 pm |
Chemical Synthesis
Discussion Leaders: Srinivas Hotha (Indian Institute of Science Education and Research, Pune, India) and George O'Doherty (Northeastern University, USA)
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9:00 am - 9:25 am |
David Crich (Wayne State University, USA)
"Saccharides, Pseudosaccharides and Their Mimetics"
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9:25 am - 9:35 am |
Discussion
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9:35 am - 10:00 am |
Maciej Walczak (University of Colorado Boulder, USA)
"Next-Generation Methods for the Synthesis of Oligosaccharides and Glycoconjugates"
|
10:00 am - 10:10 am |
Discussion
|
10:10 am - 10:20 am |
Selected from Poster Abstracts: Pavel Nagorny (University of Michigan, USA)
"New Catalytic Methods for the Synthesis of Carbohydrates"
|
10:20 am - 10:25 am |
Discussion
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10:25 am - 10:55 am |
Group Photo / Coffee Break
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10:55 am - 11:20 am |
Xin-Shan Ye (Peking University, China)
"Preactivation Strategy: A Powerful Approach to Glycan Synthesis"
|
11:20 am - 11:30 am |
Discussion
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11:30 am - 11:55 am |
Hiromune Ando (Gifu University, Japan)
"Stereoselective α-Glycosidation Using Bicyclic Sialic Acid Donors"
|
11:55 am - 12:05 pm |
Discussion
|
12:05 pm - 12:15 pm |
Selected from Poster Abstracts: Weiping Tang (University of Wisconsin-Madison, USA)
"Catalytic Site-Selective Functionalization of Carbohydrates"
|
12:15 pm - 12:20 pm |
Discussion
|
12:20 pm - 12:30 pm |
Poster Previews
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
3:00 pm - 4:00 pm |
The GRC Power Hour™
The GRC Power Hour™ is designed to address challenges women face in science and issues of diversity and inclusion. The program supports the professional growth of all members of our communities by providing an open forum for discussion and mentoring.
Organizer: Jennifer Kohler (University of Texas Southwestern Medical Center, USA)
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4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 9:30 pm |
Enzymatic and Chemoenzymatic Synthesis
Discussion Leader: Todd Lowary (University of Alberta, Canada)
|
7:30 pm - 7:55 pm |
Lai-Xi Wang (University of Maryland, College Park, USA)
"Recent Advance in Chemoenzymatic Synthesis of Glycoproteins"
|
7:55 pm - 8:05 pm |
Discussion
|
8:05 pm - 8:30 pm |
Hongzhi Cao (Shandong University, China)
"Enzymatic Modular Assembly of Human Glycans"
|
8:30 pm - 8:40 pm |
Discussion
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8:40 pm - 8:50 pm |
Selected from Poster Abstracts: Thomas Rexer (Max Planck Institute for Dynamics of Complex Technical Systems, Germany)
"Synthesis of Synthetic Lipid-Linked Oligosaccharides for In Vitro Glycoengineering of Proteins by a Cell-Free, Compartmentalized Multi-Enzyme Cascade"
|
8:50 pm - 8:55 pm |
Discussion
|
8:55 pm - 9:20 pm |
Joachim Thiem (University of Hamburg, Germany)
"Chemistry Around Transsialidases: Search for Novel Enzymes, Employment in Syntheses, and Inhibition Studies"
|
9:20 pm - 9:30 pm |
Discussion
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Tuesday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am - 12:30 pm |
Machine-Assisted Synthesis
Discussion Leaders: Alexei Demchenko (University of Missouri-St. Louis, USA) and Mads Clausen (Technical University of Denmark, Denmark)
|
9:00 am - 9:25 am |
Peter Seeberger (Max Planck Institute of Colloids and Interfaces, Germany)
"Automated Glycan Assembly of Polysaccharides: The Basis of Carbohydrate-Based Material Science"
|
9:25 am - 9:35 am |
Discussion
|
9:35 am - 10:00 am |
Peng George Wang (Georgia State University, USA)
"Exploration of Carbohydrates in Human Immunity"
|
10:00 am - 10:10 am |
Discussion
|
10:10 am - 10:20 am |
Selected from Poster Abstracts: Zhimeng Wu (Jiangnan University, China)
"Assembly of Staphylococcus aureus WTA Heptamers with Aminohexanol Spacer on Ionic Liquid Support"
|
10:20 am - 10:25 am |
Discussion
|
10:25 am - 10:55 am |
Coffee Break
|
10:55 am - 11:20 am |
Geert-Jan Boons (Utrecht University, The Netherlands)
"Streamlining the Chemoenzymatic Synthesis of Highly Complex Branched Glycans"
|
11:20 am - 11:30 am |
Discussion
|
11:30 am - 11:40 am |
Selected from Poster Abstracts: Qian Wan (Huazhong University of Science and Technology, China)
"Total Synthesis of Resin Glycosides via Interrupted Pummerer Reaction Mediated Glycosylations"
|
11:40 am - 11:45 am |
Discussion
|
11:45 am - 11:55 am |
Selected from Poster Abstracts: Justin Ragains (Louisiana State University, USA)
"New Strategies for O-Glycosylation and Latent-Active Approaches to Oligosaccharide Synthesis New Strategies for O-Glycosylation and Latent-Active Approaches to Oligosaccharide Synthesis"
|
11:55 am - 12:00 pm |
Discussion
|
12:00 pm - 12:10 pm |
Selected from Poster Abstracts: Leonid Kononov (N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Russia)
"Nano- and Mesoscale Structuring in Reaction Solutions: Possibilities to Modulate the Outcome of Glycosylation and Other Reactions with Carbohydrate Derivatives"
|
12:10 pm - 12:15 pm |
Discussion
|
12:15 pm - 12:30 pm |
Poster Previews
|
12:30 pm - 1:30 pm |
Lunch
|
2:00 pm - 4:00 pm |
Poster Session
|
4:00 pm - 6:00 pm |
Biosynthesis and Degradation Enzymes
Discussion Leader: Jian Liu (University of North Carolina at Chapel Hill, USA)
|
4:00 pm - 4:25 pm |
Bernd Nidetzky (Graz University of Technology, Austria)
"Leloir Glycosyltransferases for Chemical Production"
|
4:25 pm - 4:35 pm |
Discussion
|
4:35 pm - 5:00 pm |
Andrew Fisher (University of California, Davis, USA)
"Structures of N. meningitidis CMP-Sialic Acid Synthetase with Substrates, and a Fungal Pathogen Effector Bound to Chitin"
|
5:00 pm - 5:10 pm |
Discussion
|
5:10 pm - 5:20 pm |
Selected from Poster Abstracts: Juergen Seibel (University of Wuerzburg, Germany)
"Product-Oriented Chemical Surface Modification of Carbohydrate Active Enzymes"
|
5:20 pm - 5:25 pm |
Discussion
|
5:25 pm - 5:50 pm |
Taroh Kinoshita (Research Institute for Microbial Diseases, Osaka University, Japan)
"Side-Chain Modifications of Mammalian GPI-Anchors"
|
5:50 pm - 6:00 pm |
Discussion
|
6:00 pm - 7:00 pm |
Dinner
|
Wednesday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am - 12:30 pm |
Carbohydrate-Based Prebiotics and Therapeutics
Discussion Leaders: Timor Baasov (Schulich Faculty of Chemistry, Technion - Israel Institute of Technology, Israel) and Biao Yu (Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, China)
|
9:00 am - 9:25 am |
Rita Gerardy-Schahn (Institute for Clinical Biochemistry, Hannover Medical School, Germany)
"Next Generation Vaccines Made in Fermentation Free Chemoenzymatic Processes"
|
9:25 am - 9:35 am |
Discussion
|
9:35 am - 10:00 am |
Steven Townsend (Vanderbilt University, USA)
"Novel Strategies for Carbohydrate Synthesis and Modification"
|
10:00 am - 10:10 am |
Discussion
|
10:10 am - 10:20 am |
Selected from Poster Abstracts: Lina Cui (University of Florida, USA)
"Structurally Defined Fluorogenic Probe Enables High-Throughput Screening of Inhibitors for Heparanase"
|
10:20 am - 10:25 am |
Discussion
|
10:25 am - 10:55 am |
Coffee Break
|
10:55 am - 11:20 am |
Yukari Fujimoto (Keio University, Japan)
"Glycoconjugates: Synthesis and the Latent Functions in Immune System"
|
11:20 am - 11:30 am |
Discussion
|
11:30 am - 11:55 am |
Guangli Yu (Ocean University of China, China)
"The Effect of Marine Bioactive Polysaccharides on Gut Microbiota"
|
11:55 am - 12:05 pm |
Discussion
|
12:05 pm - 12:15 pm |
Selected from Poster Abstracts: Shino Manabe (RIKEN, Japan)
"Preparation of Homogeneous Antibody-Drug Conjugate Through Glycan Remodeling"
|
12:15 pm - 12:20 pm |
Discussion
|
12:20 pm - 12:30 pm |
Poster Previews
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 9:30 pm |
Glycoimmunology and Chemical Glycobiology
Discussion Leader: Linda Hsieh-Wilson (California Institute of Technology, USA)
|
7:30 pm - 7:55 pm |
Xing Chen (Peking University, China)
"Woe and Weal: An Unexpected S-Glycosylation in Metabolic Glycan Labeling and Cysteine Profiling"
|
7:55 pm - 8:05 pm |
Discussion
|
8:05 pm - 8:30 pm |
Mariela Segura (University of Montreal, Canada)
"Immunogenic Properties of Structurally Diverse Streptococcal Capsular Polysaccharides"
|
8:30 pm - 8:40 pm |
Discussion
|
8:40 pm - 8:50 pm |
Selected from Poster Abstracts: Vered Padler-Karavani (Tel Aviv University, Israel)
"Glycosylation Immunological Effects on Human Biodevices"
|
8:50 pm - 8:55 pm |
Discussion
|
8:55 pm - 9:20 pm |
Benjamin Davis (University of Oxford, United Kingdom)
"Sugars and Proteins"
|
9:20 pm - 9:30 pm |
Discussion
|
Thursday
|
7:30 am - 8:30 am |
Breakfast
|
8:30 am - 9:00 am |
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
|
9:00 am - 12:30 pm |
Human and Microbial Glycomes
Discussion Leaders: Jennifer Kohler (University of Texas Southwestern Medical Center, USA) and Peter Andreana (University of Toledo, USA)
|
9:00 am - 9:25 am |
Fikri Avci (University of Georgia, USA)
"Interactions of Carbohydrate Antigens with the Immune System in Health and Disease"
|
9:25 am - 9:35 am |
Discussion
|
9:35 am - 10:00 am |
Amelia Rauter (Faculdade de Ciências, Universidade de Lisboa, Portugal)
"Lipoglycosides: Synthesis and New Antimicrobial Mechanism of Action"
|
10:00 am - 10:10 am |
Discussion
|
10:10 am - 10:20 am |
Selected from Poster Abstracts: Daniel Varon Silva (Max Planck Institute of Colloids and Interfaces, Germany)
"Parasitic Glycosylphosphatidylinositols as Tools for Biomedical Research"
|
10:20 am - 10:25 am |
Discussion
|
10:25 am - 10:55 am |
Coffee Break
|
10:55 am - 11:20 am |
Kamil Godula (University of California, San Diego, USA)
"Chemical Methods for Engineering Complexity of the Cellular Glycocalyx"
|
11:20 am - 11:30 am |
Discussion
|
11:30 am - 11:55 am |
Isabelle Compagnon (Université Claude Bernard Lyon 1, France)
"Adding a Spectroscopic Dimension to Mass Spectrometry: Fundamental Aspects of Carbohydrate Structure and Application to De Novo Sequencing"
|
11:55 am - 12:05 pm |
Discussion
|
12:05 pm - 12:15 pm |
Selected from Poster Abstracts: Adam Braunschweig (Advanced Science Research Center, City University of New York, USA)
"Synthetic Carbohydrate Receptors with Potent Antiviral Activity "
|
12:15 pm - 12:20 pm |
Discussion
|
12:20 pm - 12:30 pm |
Poster Previews
|
12:30 pm - 1:30 pm |
Lunch
|
2:00 pm - 4:00 pm |
Poster Session
|
4:00 pm - 6:00 pm |
Carbohydrates in Host-Microbe Interactions
Discussion Leader: Jacquelyn Gervay-Hague (University of California, Davis, USA)
|
4:00 pm - 4:25 pm |
Laura Kiessling (Massachusetts Institute of Technology, USA)
"Examining and Exploiting Microbial Glycans"
|
4:25 pm - 4:35 pm |
Discussion
|
4:35 pm - 5:00 pm |
Chun-Hung Lin (Academia Sinica, Taiwan)
"Role of Glycosylation in Orchestrating Host Defense Against the Pathogenesis of Helicobacter pylori"
|
5:00 pm - 5:10 pm |
Discussion
|
5:10 pm - 5:20 pm |
Selected from Poster Abstracts: Steven Sucheck (The University of Toledo, USA)
"Synthesis of an Fc Domain-Enhanced Liposomal Cancer Vaccine and Bacterial Vaccine Components"
|
5:20 pm - 5:25 pm |
Discussion
|
5:25 pm - 5:50 pm |
Michael Jennings (Griffith University, Australia)
"The Structure and Function of High Affinity Glycan-Glycan Interactions in Infectious Disease"
|
5:50 pm - 6:00 pm |
Discussion
|
6:00 pm - 7:00 pm |
Dinner
|
Friday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am |
Departure
|