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Cell Biology of the Neuron (GRS)

Gordon Research Seminar

Molecular Understanding of the Neuron: Development, Plasticity and Function

June 25 - 26, 2022
Chairs Chinyere Agbaegbu Iweka and Oshri Avraham
Waterville Valley
56 Packard's Road
Waterville Valley, NH, United States
 Venue and Travel Information

Conference Description

The Gordon Research Seminar on Cell Biology of the Neuron is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting-edge ideas.

Our goal for this GRS is to foster an atmosphere and discussion that advances our understanding of cellular function of the neuron. Our program will embrace research that spans all facets of Neuronal Cell Biology, from molecular and cellular signaling, development, plasticity, trafficking, as well as disease. This meeting will feature a keynote lecture delivered by Avital Rodal, a leader in the fields of endosomal trafficking and membrane remodeling.

Attendees will participate by giving an oral presentation, serving as a discussion leader, and/or presenting a poster. In addition, we are planning a Career Development panel to provide young investigators with a "Hindsight 20/20" perspective on their developing careers.

Related Meeting

This GRS will be held in conjunction with the "Cell Biology of the Neuron" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Routing and Remodeling Membranes at Synapses
Discussion Leader: Christian Hoffmann (German Center for Neurodegenerative Diseases (DZNE), Germany)
3:45 pm - 4:15 pm
Avital Rodal (Brandeis University, United States)
"Routing and Remodeling Membranes at Synapses"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Neuronal Growth, Development and Repair
Discussion Leader: Cathleen Hagemann (Francis Crick, United Kingdom)
7:30 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:05 pm
Christabel Tan (Duke University, United States)
"Ctnnd2 Controls Layer-Specific Astrocyte Morphogenesis by Astrocyte-Neuron Cadherin Interactions Cadherin Interactions"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Andrea Cuentas-Condori (Yale University, United States)
"The Epithelial Na+ Channel, UNC-8, Triggers an Endocytic Mechanism that Recycles Presynaptic Components From Old to New Boutons in Remodeling Neurons"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Anne Quatraccioni (University of Bonn, Germany)
"Regulation of Inhibitory Synaptic Connections and Distal Neuronal Complexity by the Ste20-Like Kinase SLK"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Rajan Thakur (Brown University, United States)
"PDZD8 Promotes Autophagy at ER-Lysosome Contact Sites to Regulate Synaptic Growth"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Irene Dalla Costa (University of South Carolina, United States)
"Acetylation of Axonal G3BP1 Promotes Axon Growth"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Neuronal Plasticity and Function
Discussion Leader: Irene Dalla Costa (University of South Carolina, United States)
9:00 am - 9:20 am
Introduction by Discussion Leader
9:20 am - 9:35 am
Rachel Cain (Thomas Jefferson University, United States)
"Nanoscale Rules governing the Organization of Glutamate Receptors in Spine Synapses are Subunit Specific"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Matthew Koenig (University of Iowa, United States)
"Development of an In-Vitro Model for Axonal Proteostasis"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Cathleen Hagemann (Francis Crick, United Kingdom)
"Going the Distance: Systematically Modelling Axonal Length in Human iPSC-Derived Motor Neurons Using a Bioengineered Platform to Understand Underlying Homeostatic Mechanisms"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Tyler Ogunmowo (The Johns Hopkins University School of Medicine, United States)
"Intersectin Condensates Maintain Replacement Sites for Short Term Plasticity"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Christian Hoffmann (German Center for Neurodegenerative Diseases (DZNE), Germany)
"a-Synuclein Modulates Phase Separation of Presynaptic Condensates"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Panel
Discussion Leader: Rajan Thakur (Brown University, United States)
1:30 pm - 2:30 pm
Panel Discussion
Career Panel: 50/50 Hindsight
  • Dan Carlin (Alexion, AstraZeneca Rare Disease, United States)
  • Miriam Leenders (National Institute of Neurological Disorders and Stroke, NIH, United States)
  • Avital Rodal (Brandeis University, United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes

Contributors

National Institutes of Health (NIH)
Bio-Techne
Partek
10x Genomics, Inc

Research reported in this publication was supported by the National Institute Of Neurological Disorders And Stroke of the National Institutes of Health under Award Number R13NS116968. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Conference Links

Conference History Cell Biology of the Neuron
Additional Fee Info

Cell Biology of the Neuron
June 23 - 28, 2024


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