1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: The Many Layers of the Centromere
Welcome by Co-Chairs: Samuel Corless, Karlsruhe Institute of Technology; Maiko Kitaoka, University of California, Berkeley
Daniele Fachinetti (Institut Curie, France)
3:45 pm - 4:15 pm
Beth Sullivan (Duke University, United States) "A Centromere Journey: From Sequence to Epigenetics and Back Again"
4:15 pm - 4:30 pm
4:30 pm - 6:00 pm
6:00 pm - 7:00 pm
7:30 pm - 9:30 pm
Centromeric Chromatin: Bridging Structure and Function
4 talks by trainees selected from the abstracts
Andrea Musacchio (Max Planck Institute of Molecular Physiology, Germany)
7:30 pm - 7:50 pm
Glennis Logsdon (University of Washington, United States) "New Insights into the Variation and Evolution of Human Centromeres"
7:50 pm - 8:00 pm
8:00 pm - 8:20 pm
Stanislau Yatskevich (MRC Laboratory of Molecular Biology, United Kingdom) "Structure of the Human Inner Kinetochore Bound to a Centromeric CENP-A Nucleosome"
8:20 pm - 8:30 pm
8:30 pm - 8:50 pm
Catalina Salinas Luypaert (Institut Curie, France) "Revealing the Role of DNA Methylation in the Specification and Maintenance of Centromere Identity, Integrity and Function"
8:50 pm - 9:00 pm
9:00 pm - 9:20 pm
Nuno Martins (Harvard Medical School, United States) "Visualizing the Genomic Nano-Architecture of Interphase and Mitotic Centromeres Using OligoSTORM"
9:20 pm - 9:30 pm
7:30 am - 8:30 am
9:00 am - 11:00 am
Molecular Players: From DNA to Microtubule
3 talks by trainees selected from the abstracts
Takashi Akera (National Institutes of Health, United States) and Elaine Dunleavy (National University of Ireland Galway, Ireland)
9:00 am - 9:15 am
Arunika Das (University of Pennsylvania, United States) "Centromere Chromatin is Maintained Through the Extended Prophase I Arrest in Mammalian Oocytes Without New Assembly"
9:15 am - 9:20 am
9:20 am - 9:35 am
Ayantika Sen Gupta (Stowers Institute for Medical Research, United States) "Geometry of Human Centromeres During Mitosis"
9:35 am - 9:40 am
9:40 am - 9:55 am
Max Haase (NYU Langone Health, United States) "Evolution of
Perfect Euploidy Despite Persistent Centromere Catastrophe"
9:55 am - 10:00 am
10:00 am - 11:00 am
Enacting Positive Change in our Spaces
Needhi Bhalla (University of California, Santa Cruz, United States)
Nicole Williams (500 Women Scientists, United States)
11:00 am - 12:30 pm
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
1:30 pm - 2:30 pm
Centromere Dysfunction in Aneuploidy and Disease
2 talks by trainees selected from the abstracts
Yukiko Yamashita (Whitehead Institute/MIT/HHMI, United States)
1:30 pm - 1:50 pm
Warif El Yakoubi (NHLBI-NIH, United States) "Condensation Defects of Pericentromeric Major Satellite DNA Underlie Subfertility in Hybrid Female Mice"
1:50 pm - 2:00 pm
2:00 pm - 2:20 pm
Ana Stankovic (Brain Research Institute, University of Zurich, Switzerland) "Repurposing of CENP-A for neuronal activation"
2:20 pm - 2:30 pm
2:30 pm - 3:00 pm
Complete the GRS Evaluation Forms; Election of Future Chair(s)