Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Diverse Views of Chromosome Biology
7:40 pm - 7:45 pm
Opening Remarks
7:45 pm - 8:10 pm
"Condensin-Based
Chromosome Organization"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
"Chromosome Segregation in Archaea: A Thermophilic Menage a Trois"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Imaging the Three-Dimensional Genome Organization in
Single Cells"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Interplay Between Chromosome Segregation, Replication and Cell Division in Pseudomonas aeruginosa "
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Regulation
of Transcription and Replication by Nucleoid-Associated Proteins"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Global
Chromosome Dynamics from Bacteria to Mammalian Cells"
10:20 am - 10:30 am
Discussion
10:30 am - 10:40 am
"Actively Transcribed rRNA Genes Contribute to Nucleoid Resolution in Bacillus subtilis Due to Binding of the Smc-ScpAB Condensin Complex"
10:40 am - 10:45 am
Discussion
10:45 am - 11:15 am
Coffee Break
11:15 am - 11:35 am
"Chromosome Unfolding and Gene
Regulation by Distant Enhancers"
11:35 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Intracellular Long-Range Communication and Chromosomal Positioning Mechanisms in Cell Division"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Cell-Specific Long-Range Low-Frequency Interactions Regulate the Higher-Order Architecture of the Drosophila Genome"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Centromeres, Telomeres and Chromosome Stability
6:00 pm - 6:20 pm
"Noncanonical Roles of Telomeres and Centromeres in Controlling the Cell Cycle"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
"Single-Molecule Experiments to Resolve Structural and Mechanical Properties of Condensin"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 7:05 pm
"Preventing Chromosome Instability: Molecular
Mechanisms of Mitotic Error correction"
7:05 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
"Mechanisms to Maintain Centromere Stability in Human Cells"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"TZAP: A Novel Telomere-Associated Protein Involved in Telomere Length Control"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"The Dynamics of ParA-DNA and ParA-ParB Interactions During P1 Plasmid Partition"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Mechanical Architecture and Function
of the Mammalian Spindle"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Coordination of Replication and
Division Cycles"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Phase-Separation
Behavior of Heterochromatin Suggests New Avenues for Cancer Therapeutics"
10:20 am - 10:30 am
Discussion
10:30 am - 10:40 am
"Chromatin Is a Major Determinant of Nuclear Mechanics and Morphology"
10:40 am - 10:45 am
Discussion
10:45 am - 11:15 am
Coffee Break
11:15 am - 11:35 am
"Modeling Replication
Conflicts and Segregation Dynamics"
11:35 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Chromosome Dynamics Probed by Single-Molecule Enzymology and Single-Cell Genomics"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Structure of Full-Length Smc and Rearrangements Required for Chromosome Organization"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Genome Structure and Dynamics
6:00 pm - 6:20 pm
"Replication-Transcription
Conflicts"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"The
Nature of Mutations Induced by Replication-Transcription Conflict"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Role
of Chromosome Structure in the Regulation of X-Chromosome-Wide Gene Expression"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"Replication Stress Restricts Ribosomal DNA Copy Number"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Direct Imaging of the Circular Chromosome in E. coli "
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Chromosome Dynamics and Cancer
9:00 am - 9:20 am
"Folding
and Segregating Chromosomes: Implications for Genome Stability and Epigenetic Inheritance"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Is Heterochromatin Just a Phase?"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Regulation of the Mitotic Chromosome Surface During Nuclear Assembly"
10:20 am - 10:30 am
Discussion
10:30 am - 10:40 am
"Sizing Up the Spindle Checkpoint"
10:40 am - 10:45 am
Discussion
10:45 am - 11:15 am
Coffee Break
11:15 am - 11:35 am
"Non-Canonical Mechanisms that Detect and Respond to Errors During Cell Division"
11:35 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"RNA Dependent Control of Chromatin Silencing"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Condensin I Directs Sister Chromatid Resolution Throughout Metaphase"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
6:00 pm - 6:20 pm
"Kinetochore
Remodeling During Meiosis Through the Regulation of Hec1"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Spo11, a 'Broken' Topoisomerase"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"The Causes of Chromosome Segregation
Errors in Mammalian Oocytes"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"The Role of Telomerase Dependent Attachments in Ensuring Meiotic Chromosome Motion"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"RNA-Associating Proteins Accumulated on the Chromosome During Homologous Chromosome Pairing in Meiosis"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
Chromosome Cohesion and Condensation
9:00 am - 9:20 am
"Single-Nucleus Hi-C Reveals Unique Chromatin Reorganization During the Oocyte-to-Zygote Transition"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Structural and Mechanistic Insight into Cohesin Loading and Release"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Wapl, Pds5A and Pds5B Control Chromatin Compartments, TADs and Loops by Regulating Cohesin-DNA Interactions"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Fast Switches for a Slow Enzyme: Rescuing the Chromosome Condensation Machinery from the Chromatin Trap"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Role of Condensin in the Regulation of Gene Expression in Fission Yeast"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"The Smc5/6 Complex - Connecting DNA Supercoiling with Chromosome Segregation"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"The Roles of HAWK Subunits in Loading, Maintaining, and Releasing Cohesin from Chromosomes"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Structural Basis for Anchoring Eukaryotic Condensin to Chromosomes"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"New Integral Components of the E. coli and Salmonella SMC Complex"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Chromosome Replication and Repair
6:00 pm - 6:20 pm
"Archeal DNA Replication"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
"A Mechanism of Replication Licensing in Bacteria: A Locus on Chr1 Licenses the Replication of Chr2 in Vibrio cholerae "
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
"The Abundance of Fob1p Modulates the Efficiency of rRFBs to Stall Replication Forks"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Regulation and Mechanism of Eukaryotic DNA Replication Initiation"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"A Compartmentalized Circuit Mediates Meiotic Crossover Control"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure