Clocks Across the Phylogenetic Tree, from Single Cell to Humans

The Chronobiology GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

The field of chronobiology is a rich area that encompasses single cell organisms all the way to humans. The concept of chronobiology is simplified by the Eskinogram, where an input changes the phase of an oscillator and leads to changes in the output. This happens in bacteria, fungi, plants and animals. In a way, circadian rhythms may have been the earliest brain, where environmental input is interpreted by the brain and then leads to an action. The inputs to the clock are the simple, light and temperature, to the complex, social interactions. The oscillators are varied molecular machines that have transcription, translation and posttranslational modifications. The outputs control all aspects of the organisms’ physiology and behavior.