Conference Description
The Cilia, Mucus and Mucociliary Interactions GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.
Since 2005, the Cilia, Mucus, and Mucociliary Interactions GRC has brought together world-class investigators to discuss the latest topics focused on furthering our understanding of the processes which underline mucociliary clearance system in health and disease. This conference provides a unique opportunity for basic scientists and clinical researchers interested in these interrelated areas to discuss their latest findings and learn about new technologies that provide novel approaches to current challenges. This conference attracts a broad array of scientists ranging from biophysicists and biochemists to physiologists, geneticists, and developmental biologists. In addition to its biological and biophysical focus, a key differentiating aspect of this conference has, and continues to be, the inclusion of new scientific understanding, and technology associated with understanding, the structure and function of cilia and mucins, and how these critical components interact to protect the airway surfaces. The overarching theme of the 2023 conference will be "Integrating our understanding of cilia and mucus from gene regulation to protein structure to function". Therefore, this conference will feature a diverse community of academic and industrial researchers working on efforts in structural biology, bioengineering, biophysics, biochemistry, and embryology, many seeking to solve clinically relevant biomedical problems relating to mucus/mucins and cilia, including SARS-CoV-2 infection. Key topics of this conference revolve around the latest information on basic mechanisms of cellular assembly, processing, and function, and the relationship between motile cilia, mucus and related features that are an essential component of fundamental biological processes. As such, issues related to multiple disciplines will be embraced. Additionally, the 2023 program will continue our rich conference history in providing excellent opportunities for junior investigators to present their work and exchange ideas in a collegial atmosphere with experts in the field. There will be poster sessions organized on topical themes to match the session topics. Bringing together this community of students, scientists, and clinicians, to share the most recent insights and understanding of cilia and mucus – from the perspective of their respective disciplines – will allow the sharing of new ideas and methodologies, mutual learning, and, importantly, the opportunity to develop new collaborations – all with the goal of improving our understating of the mucociliary clearance system in health and disease.
The topics, speakers, and discussion leaders for the conference sessions are displayed below. The conference chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by October 22, 2022. Please check back for updates.
Keynote Session: Prospects and Themes
Discussion Leaders
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Matthias Salathe (University of Kansas Medical Center, United States)
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Mary Porter (University of Minnesota, United States)
Speakers
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Susan Dutcher (Washington University in St. Louis, United States)
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Christopher Evans (University of Colorado School of Medicine, United States)
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Steven Brody (Washington University School of Medicine, United States)
Genetic and Molecular Understanding of Mucociliary Disorders
Discussion Leaders
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Hannah Mitchison (University College London, United Kingdom)
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Max Seibold (National Jewish Health, United States)
Speakers
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Peter Jackson (Stanford University School of Medicine, United States)
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Kenichi Okuda (University of North Carolina at Chapel Hill, United States)
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Julia Wallmeier (University of Münster, Germany)
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John Fahy (University of California, San Francisco, United States)
Systems Biology
Discussion Leaders
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Sudipto Roy (Institute of Molecular and Cell Biology, A*STAR, Singapore)
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Jean-Luc Desseyn (Univ. Lille/Inserm/CHU Lille, France)
Speakers
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Sophie Darch (University of South Florida, United States)
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Silvia Kreda (CF Center, University of North Carolina at Chapel Hill, United States)
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Wallace Marshall (University of California, San Francisco, United States)
Mucin and Cilia Biophysics
Discussion Leaders
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David Hill (University of North Carolina at Chapel Hill, United States)
Speakers
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Zeynep Ökten (Technical University of Munich, Germany)
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Elisabeth Nystrom (University of Kiel/ University of Gothenburg, Sweden)
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Kirsty Wan (University of Exeter, United Kingdom)
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Susan Birket (University of Alabama at Birmingham, United States)
Structure and Function
Discussion Leaders
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Laura Campbell (University of Manchester, United Kingdom)
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Speakers
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Daniela Nicastro (University of Texas Southwestern Medical Center, United States)
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Deborah Fass (Weizmann Institute of Science, Israel)
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Katerina Toropova (Birkbeck, University of London, United Kingdom)
Signaling and Host Defense
Discussion Leaders
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Anna Ermund (University of Gothenburg, Sweden)
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Speakers
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Julia Duerr (Charité - Universitätsmedizin Berlin, Germany)
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Hiroshi Hamada (RIKEN Center for Biosystems Dynamics Research, Japan)
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Shiaulou Yuan (Massachusetts General Hospital / Harvard Medical School, United States)
Regulation and Function
Discussion Leaders
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Nathalie Jurisch-Yaksi (Norwegian University of Science and Technology, Norway)
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Corrine Kliment (University of Pittsburgh School of Medicine, United States)
Speakers
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Luke Bonser (University of California, San Francisco, United States)
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Dagmar Wachten (Institute of Innate Immunity, University of Bonn, Germany)
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John Dickinson (University of Nebraska, United States)
Disease Modeling
Discussion Leaders
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Nam Soo Joo (Stanford University, United States)
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Brian Mitchell (Northwestern University, United States)
Speakers
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Mustafa Khokha (Yale University School of Medicine, United States)
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John Engelhardt (University of Iowa, United States)
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Rebecca Burdine (Princeton University, United States)
Technologies to Study Cilia, Mucus and Mucociliary Interactions
Discussion Leaders
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Alessandra Livraghi-Butrico (University of North Carolina at Chapel Hill, United States)
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Benedicte Durand (University Claude Bernard Lyon-1, France)
Speakers
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Jessica Kramer (University of Utah, United States)
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Raman Das (University of Manchester, United Kingdom)
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David Stoltz (University of Iowa, United States)
The GRC Power Hour™