Sunday
2:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Beyond the Boundaries of Diagnoses Across the Lifespan
This session will highlight the dimension of cognitive dysfunction across major brain diseases in different age groups, drawing the similarity beyond current framework for diagnostic classifications.
7:40 pm - 8:15 pm
"Plasticity, Pathology and Cognitive Function Across Age and Diagnosis"
8:15 pm - 8:35 pm
Discussion
8:35 pm - 9:10 pm
"Cognitive and Behavioural Dysfunction in Huntington's Disease: Associations and Mechanisms"
9:10 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Genetics and Behavior
Advanced genetic evaluation has
provided important insights into the development of major neuropsychiatric
conditions. Recent explorations appear to inform the clustering of
constitutional predisposed physiological functions that modulate behaviors
independent of diagnosis. This session will draw the links between genetic
studies, cognitive and behavioral disorders.
9:00 am - 9:40 am
"Insights from Common Variant Analysis in Schizophrenia About the Genetic Architecture of Cognition"
9:40 am - 10:00 am
Discussion
10:00 am - 10:30 am
Group Photo / Coffee Break
10:30 am - 11:10 am
"Multimodal Phenotypic Evaluation for Psychosis"
11:10 am - 11:30 am
Discussion
11:30 am - 12:10 pm
"The Gap Between Gene and Behavior in Mental Disorder Studies – A Neuroimaging Perspective"
12:10 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Imaging Cognitive Function and Dysfunction in Alzheimer's Disease and Other Neurocognitive Disorders
The state of the art neuroimaging techniques in elucidating underlying mechanisms for cognitive dysfunction will be introduced. Presentations will expand from the framework of degenerative conditions to other brain disorders.
7:30 pm - 8:10 pm
"Neuroimaging for Small Vessels of the Brain – Implications on Cognition"
8:10 pm - 8:30 pm
Discussion
8:30 pm - 9:10 pm
"Functional Network Organization in the Early Stages of Alzheimer's Disease"
9:10 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Physical Activity, Nutrition and the Ageing Brain
There has been increasing interests in the
relationship between physical activity, diet and brain function. The protective
effects of these lifestyle activities in cognition have mostly been evaluated
in older adults. However, the putative mechanisms are not only specific for the
ageing brain. This session will discuss on the potential for further research
beyond the current paradigm.
9:00 am - 9:40 am
"Physical Activity and Brain Reserve – A Possible Transdiagnostic Intervention"
9:40 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 11:10 am
"Effects of Lifestyle Behaviors on the Brain: Immediate Versus Longterm"
11:10 am - 11:30 am
Discussion
11:30 am - 12:10 pm
"Nutrition and Brain Imaging Biomarkers: Where Are We and Where Do We Want to Be?"
12:10 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
2:00 pm - 4:00 pm
Poster Session
4:00 pm - 6:00 pm
Translational Cognitive
Neuroscience
Basic neuroscience research
provides models for diseases that are associated with cognitive dysfunction.
This session draws on the significance of translation into potential clinical
inference through different approaches.
4:00 pm - 4:40 pm
"Oscillations and Neuronal Dynamics in Schizophrenia: The Search for Basic Symptoms and Translational Opportunities"
4:40 pm - 5:00 pm
Discussion
5:00 pm - 5:40 pm
"Transgenic and
Knockout Mouse Models for Vascular Mechanisms in Neurodegenerative Disorders"
5:40 pm - 6:00 pm
Discussion
6:00 pm - 7:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Inflammation, Immunity and Neuroplasticity
Interests in inflammation and immunity as important mechanisms for brain disorders arose from findings of basic neuroscience research and genetic studies of susceptibility gene loci. This session will explore the mechanisms leading to brain dysfunction, as well as potential for intervention that may modify disease course.
9:00 am - 9:40 am
"Impact of Systemic Inflammation on Neuroinflammation, Cognitive Functions and Neurodegeneration"
9:40 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 11:10 am
"Bidirectional Changes in Plasticity Regulated by an Innate Immune Receptor in Neurons – An Endocannabinoid Connection"
11:10 am - 11:30 am
Discussion
11:30 am - 12:00 pm
"Effect of Physical Exercise on Clinical Outcome Measures, Cognition and the Brain – A Transdiagnostic Therapeutic Prospect"
12:00 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 8:30 pm
Traumatic
Brain Injury
Severe traumatic brain
injury (TBI) is well recognized cause for brain damage. Other TBIs may escape
clinical attention, and lead to under-recognition of behavioral changes
associated with cognitive impairments. This session will draw attention to
newly explored risk factors between TBI and cognitive dysfunction.
7:30 pm - 8:10 pm
"Altered Cerebellar Anatomical Connectivity in Patients with Mild Traumatic Brain Injury"
8:10 pm - 8:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
Sleep, Biological Rhythm and Neurodegeneration
Sleep and biological rhythms are not only basic physiological function, but also are recognized important clinical manifestations of brain diseases. This session brings into spotlight that biorhythm studies may inform new direction for research in cognitive and neuropsychiatric disorders.
9:00 am - 9:40 am
"Neural Circuits Controlling Sleep"
9:40 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 11:10 am
"Dysynchrony of Homeostatic Rhythms in Bipolar Disorder"
11:10 am - 11:30 am
Discussion
11:30 am - 12:10 pm
"Sleep Disturbance and Circadian Disruption as Biomarker and Pathogenesis of Psychiatric and Neurodegenerative Disorders"
12:10 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Towards Intervention for Brain Reserve
This session will provide an
integrative framework towards the possibility of multimodality intervention to
enhance neuroplasticity for cognitive dysfunction from a transdiagnostic
perspective.
4:00 pm - 4:30 pm
"Multi-Nutrient Intervention in Pre-Dementia Alzheimer's Disease"
4:30 pm - 4:40 pm
Discussion
4:40 pm - 5:10 pm
"Neurogenesis in the Live Human Brain: A New MR Spectroscopi Method and Functional Relevance to Psychiatry, Neurodegeneration and Intervention-Related Plasticity"
5:10 pm - 5:20 pm
Discussion
5:20 pm - 5:50 pm
"A Life Course Approach to Optimizing Cognitive Reserve?"
5:50 pm - 6:00 pm
Discussion
6:00 pm - 7:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure