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Proteolytic Enzymes and Their Inhibitors
Gordon Research Conference

Conference Information

Status

Active

Initial Year

1980

Discipline

Biological

Categories

Meeting Cycle

24 Months

Conference Description

Proteases play key roles in virtually every aspect of cell biology and every function of multicellular organisms. They are essential in such fundamental cell processes as separation of chromosomes during mitosis, cell-cycle control, apoptosis, and signal transduction. At the organismal level, these enzymes control such processes as wound healing, antigen presentation, reproduction, and neo-vascularization. Disregulation of proteases leads to or exacerbates an array of human pathologies including arthritis, stroke, dementia, metabolic disorders, blood coagulation defects, and cardiomyopathy. And infectious agents utilize proteases to mount their attacks.

This Gordon Research Conference traditionally deals with the structure, function, and regulation of these enzymes and, increasingly, with their physiological roles. There are typically also some talks on developments in techniques, such as mass spec identification of substrates and imaging proteolytic activity at the cell and whole-organism level. Areas of physiology usually covered include inflammation and immunology, cancer, cell death, and infectious disease, with additional areas varying from year-to-year. There is always a session on synthetic inhibitors, generally covering compounds going into the clinic. The conference is attended by biochemists, synthetic chemists, crystallographers, kineticists, experts in mass spectrometry, investigators of new biological imaging techniques, biologists and protein chemists.

What is a GRC? Gordon Research Conferences (GRC) are 5-day meetings that bring scientists together from around the world to present and discuss unpublished research with other leaders in their field.

Related Conference

This Gordon Research Conference (GRC) series is related to the "Proteolytic Enzymes and Their Inhibitors" Gordon Research Seminar (GRS) series. Although a related GRS will typically be scheduled in conjunction with its parent GRC each time it meets, that may not always be the case. Refer to the individual meetings in the Meeting History section below for more details. For more information about the associated Gordon Research Seminar (GRS) series, click here.

What is a GRS? Gordon Research Seminars (GRS) are 2-day meetings that bring graduate students and post-docs together to discuss their cutting edge research among peers and mentors. Each GRS immediately precedes an associated Gordon Research Conference (GRC), and topics addressed at the GRS relate closely to the GRC.

Meeting History

YearMeeting NameDatesConference SiteChair(s)
2018 Proteolytic Enzymes and Their Inhibitors
Understanding Proteases and Their Roles as Regulators of Health and Disease
Jun 3-8 Renaissance Tuscany Il Ciocco Matthew S. Bogyo
2016 Proteolytic Enzymes and Their Inhibitors
Exploring and Exploiting Proteases in Development and Disease
Jun 26 - Jul 1 Renaissance Tuscany Il Ciocco Johanna A. Joyce
2014 Proteolytic Enzymes and Their Inhibitors
Dysfunction in Disease, Mechanism and Therapeutic Targeting
Jun 22-27 Renaissance Tuscany Il Ciocco James C. Whisstock
2012 Proteolytic Enzymes and Their Inhibitors
Proteolysis: The Most Important Post Translational Modification Regulating Biology, Life and Death of Every Cell
Jun 17-22 Renaissance Tuscany Il Ciocco Klaudia Brix
2010 Proteolytic Enzymes and Their Inhibitors
Proteolysis: The Most Important and Ubiquitous Post Translational Modification that Regulates Biology, Life and Death
May 2-7 Renaissance Tuscany Il Ciocco Christopher M. Overall
2008 Proteolytic Enzymes and Their Inhibitors Jul 6-11 Colby-Sawyer College Jan Potempa
2006 Proteolytic Enzymes and Their Inhibitors Jul 2-7 Colby-Sawyer College Roy A. Black
2004 Proteolytic Enzymes and Their Inhibitors Jul 4-9 Colby-Sawyer College Nancy A. Thornberry
2002 Proteolytic Enzymes and Their Inhibitors Jul 7-12 Colby-Sawyer College James McKerrow
2000 Proteolytic Enzymes and Their Inhibitors Jul 9-14 Colby-Sawyer College Wolfram Bode
1998 Proteolytic Enzymes and Their Inhibitors Jul 5-10 Colby-Sawyer College Charles S. Craik
1996 Proteolytic Enzymes and Their Inhibitors Jul 21-26 Colby-Sawyer College Guy Salvesen
1994 Proteolytic Enzymes and Their Inhibitors Jul 24-29 Colby-Sawyer College Ben M. Dunn
1992 Proteolytic Enzymes and Their Inhibitors Jun 8-12 Holderness School Salvatore V. Pizzo
1990 Proteolytic Enzymes and Their Inhibitors Jun 11-15 Holderness School Alan J. Barrett
1988 Proteolytic Enzymes and Their Inhibitors Jun 13-17 Holderness School Peter Harpel
1986 Proteolytic Enzymes and Their Inhibitors Jun 16-20 Plymouth State College Elliott Shaw
1984 Proteolytic Enzymes and Their Inhibitors Jun 18-22 Plymouth State College Aaron Janoff
1982 Proteolytic Enzymes and Their Inhibitors Jun 28 - Jul 2 Plymouth State College Michael Laskowski
1980 Proteolytic Enzymes and Their Inhibitors Jun 23-27 Plymouth State College James C. Powers
James Travis
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