Gordon Research Conferences
Conference Details

Protein Processing, Trafficking and Secretion
Gordon Research Conference

Conference Information



Initial Year





Meeting Cycle

24 Months

Conference Description

This conference series, initiated in 1994 by Drs. Michel Chrétien and Donald Steiner, was originally called “Hormonal and Neural Peptide Biosynthesis”. It has since grown into a major international forum for the discussion of new research developments related to the post-translational processing, trafficking and secretion of bioactive peptides and other secretory pathway proteins, as well as the significance of these processes to human disease and cellular physiology. These include protein folding events in the endoplasmic reticulum; all post-translational processing steps including structural, biochemical and cellular analyses of endo- and exoproteolysis and N- and C-terminal modifications; intra-Golgi and post-Golgi sorting events; mechanisms of vesicle formation and trafficking; and molecular mechanisms of regulated and constitutive secretion. Studies on the implications of defective processing for physiology and disease, as well as the development of animal models and silencing techniques for various protein/enzyme targets are some of the main attractions of this meeting. An additional important focus is on emerging functions of processing enzymes, including intramembrane proteolysis, and the associated pathologies whose underlying basis relates to protein processing and/or cellular trafficking. Thus, the meeting addresses core translational biology issues of importance to various pathologies and to the development of novel therapeutics. These include childhood diseases, neuroendocrine disorders such as diabetes, and neurodegenerative diseases such as Alzheimer's disease, dyslipidemias such as hypercholesterolemia and atherosclerosis, chronic pain, hypertension, viral glycoprotein and microbial maturation, cancer/metastasis, and many others.

What is a GRC? Gordon Research Conferences (GRC) are 5-day meetings that bring scientists together from around the world to present and discuss unpublished research with other leaders in their field.

Related Conference

This Gordon Research Conference (GRC) series is related to the "Protein Processing, Trafficking and Secretion" Gordon Research Seminar (GRS) series. Although a related GRS will typically be scheduled in conjunction with its parent GRC each time it meets, that may not always be the case. Refer to the individual meetings in the Meeting History section below for more details. For more information about the associated Gordon Research Seminar (GRS) series, click here.

What is a GRS? Gordon Research Seminars (GRS) are 2-day meetings that bring graduate students and post-docs together to discuss their cutting edge research among peers and mentors. Each GRS immediately precedes an associated Gordon Research Conference (GRC), and topics addressed at the GRS relate closely to the GRC.

Meeting History

YearMeeting NameDatesConference SiteChair(s)
2018 Protein Processing, Trafficking and Secretion
Molecular Mechanisms and Translational Approaches to Cancer, Diabetes, Dyslipidemia, Cardiovascular and Neurodegenerative Disorders
Jul 15-20 Colby-Sawyer College Klaudia Brix
2016 Protein Processing, Trafficking and Secretion
Secretory and Endocytic Pathways in Health and Disease
Jul 24-29 Colby-Sawyer College Paul H. Taghert
2014 Protein Processing, Trafficking and Secretion
At the Crossroads of Understanding the Maturation and Transport of Proteins/Peptides and the Therapeutic Applications of Post-Translational Modulation
Jul 20-25 Colby-Sawyer College John W. Creemers
2012 Proprotein Processing, Trafficking and Secretion Jul 15-20 Colby-Sawyer College Lloyd D. Fricker
2010 Proprotein Processing, Trafficking and Secretion
Latest Insights into Molecular Mechanisms, Disease and Therapeutic Applications
Jul 18-23 Colby-Sawyer College Robert Day
2008 Proprotein Processing, Trafficking and Secretion Jul 13-18 Colby-Sawyer College Richard E. Mains
2006 Proprotein Processing, Trafficking and Secretion Jul 9-14 Colby-Sawyer College Nabil G. Seidah
2004 Proprotein Processing, Trafficking and Secretion Jul 11-16 Colby-Sawyer College Iris Lindberg
2002 Hormonal and Neural Peptide Biosynthesis Jul 21-26 Colby-Sawyer College Gary Thomas
2000 Hormonal and Neural Peptide Biosynthesis Jul 16-21 Colby-Sawyer College Robert S. Fuller
1998 Hormonal and Neural Peptide Biosynthesis Aug 9-14 New England College Betty A. Eipper
1996 Hormonal and Neural Peptide Biosynthesis Jul 28 - Aug 2 New Hampton School Donald F. Steiner
1994 Hormonal and Neural Peptide Biosynthesis Aug 7-12 Plymouth State College Michel Chretien
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