Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: 50 Years of Positional Information
7:40 pm - 7:45 pm
Introduction by Discussion Leader: Positional Information in 2019
7:45 pm - 8:10 pm
"50(+1) Years of the French Flag Problem"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
"Boundary Formation by Mobile Small RNAs"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Mechanical Forces and Epithelial Morphogenesis"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Orchestration of Cellular Spatial Information and Differentiation: ERK Signaling in Germ Cell Development"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Human Time vs Mouse Time in the Segmentation Clock"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Out with the Old, in with the New: ERK Coordinates Cell Fate Rewiring in Early Development"
10:15 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:10 am
"Studying Human Cerebral Cortex Development in Health and Disease with Stem Cell Systems"
11:10 am - 11:20 am
Discussion
11:20 am - 11:35 am
"An Enriched Network Motif Family Regulates Multistep Cell Fate Transitions with Restricted Reversibility"
11:35 am - 11:40 am
Discussion
11:40 am - 11:55 am
"Uncovering the Developmental Rules for Kidney Duct Morphogenesis by Programming Mesenchymal Remodeling in Space and Time"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Towards In Vitro Precision In Vivo
7:30 pm - 7:50 pm
"How Tissue Geometry and Mechanics Regulate Signaling During Gastrulation"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Dynamics of Cell Polarity Signaling in Early Development"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Recreating Human Kidney Tissue from Stem Cells: How Well Are We Mimicking What We Know of Normal Development?"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:15 pm
"Engineering of Multicellular Organization and Morphogenesis of Human Pluripotent Stem Cells Using Automated Prediction"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Cell Identity and Robustness in the Era of Single-Cell 'Omics
9:00 am - 9:20 am
"Epigenetic Recovery from Transgenerational RNA Silencing in the C. elegans Germline"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Cellular Biographies: Reconstructing Developmental Trajectories and Lineages"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Single-Cell Transcriptomics of the Acoel Hofstenia Reveals the Evolution of Bilaterian Cell Types and Stem Cell Regulation"
10:15 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:10 am
"Stochastic Regulation of G1 Duration Controls Terminal Cell Differentiation and Cell Cycle Exit"
11:10 am - 11:20 am
Discussion
11:20 am - 11:35 am
"Single Cell Transcriptomics Reveals Spatial and Temporal Dynamics of Gene Expression in the Developing Mouse Spinal Cord"
11:35 am - 11:40 am
Discussion
11:40 am - 11:55 am
"Single-Cell Analysis of Cell Fate Plasticity During Regeneration in Drosophila "
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Chromatin and Epigenetic Influences on Cell Identity
7:30 pm - 7:50 pm
"Evolution and Function of Vertebrate-Specific Atypical Notch Ligand"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Hox Binding Logic During Spinal Cord Patterning"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Reprogramming of Cell Fate and Function in the Context of Chromatin"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:15 pm
"The Transcriptional Environment in the Nucleus Becomes Increasingly Heterogeneous as Embryonic Development Progresses"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Dynamic Imaging and Imaging Dynamics
9:00 am - 9:20 am
"The Root Endodermis: An Independent Way of Building a Polarised Epithelium"
9:20 am - 9:30 am
Discussion
9:30 am - 9:45 am
"Tracing the Origin of Adult Intestinal Stem Cells"
9:45 am - 9:50 am
Discussion
9:50 am - 10:05 am
"Building the Best Barrier: How Cell Competition Shapes Epidermal Morphogenesis"
10:05 am - 10:10 am
Discussion
10:10 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"Real-Time Developmental Biology with a Shareable Microscopy Platform"
11:05 am - 11:15 am
Discussion
11:15 am - 11:30 am
"Dynamics of the SHR-SCR Network Controlling Asymmetric Cell Division"
11:30 am - 11:35 am
Discussion
11:35 am - 11:50 am
"Expanding the Fluorescent Reporter Toolkit in Mouse Using a Novel CRISPR-Mediated Genome Editing Method"
11:50 am - 11:55 am
Discussion
11:55 am - 12:00 pm
General Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
7:30 pm - 7:55 pm
"BMP Morphogen Gradient Formation and Interpretation (Positional Information Session Redux)"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Obligate Endosymbiosis in Ants Reveals Developmental Steps to Major Evolutionary Transitions"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Patterning Morphogenesis via the Planar Cell Polarity Pathway"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:20 pm
"Multi-Scale Coordination of Planar Cell Polarity in Planarians"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Metabolism and Growth Control
9:00 am - 9:20 am
"The Role of the Dilp8/Lgr3 Pathway in Adjusting Final Organ Size and Minimizing Developmental Noise"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Cell Competition and the Regulation of Growth in the Early Mouse Embryo"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Structural Basis for Cholesterol Transport-Like Activity of the Hedgehog Receptor Patched"
10:15 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:10 am
"Metabolic Adaptation in Cavefish"
11:10 am - 11:20 am
Discussion
11:20 am - 11:35 am
"Coordinating Organ Growth and Patterning in the Developing Larvae "
11:35 am - 11:40 am
Discussion
11:40 am - 12:00 pm
"The Energetic Costs of Early Development"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:25 pm
"A Single-Cell Reconstruction of Planarian Regeneration"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Developmental Robustness in Noisy Systems
7:30 pm - 7:50 pm
"How Fluctuations in a Transcription Factor Initiate Cell Patterning in Arabidopsis Sepals"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Precision in a Rush: Cell Fate Decisions from Time Dependent Data"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Inferring Context-Dependent Transcriptional Regulation from Cell-Lineage Data"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:15 pm
"Contributions of Fate Plasticity and Mechanics to Vein Patterning in the Drosophila Wing"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure