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Directed Cell Migration (GRS)

Gordon Research Seminar

Cellular Dynamics at the Interface of Molecules, Signals and Forces

January 19 - 20, 2019

Chairs Suvrajit Saha and Florian Gaertner

Grand Galvez

2024 Seawall Boulevard

Galveston, TX, United States

Venue and Travel Information

Conference Description

The 2019 Gordon Research Seminar (GRS) on Directed Cell Migration provides a unique forum for postdoctoral trainees and graduate students to present and discuss new results and cutting-edge ideas. Cellular dynamics and migration is a fundamental process not only underlying morphogenesis, development and homeostasis; but also implicated in a variety of diseases. As a result, the field has evolved into a truly transdisciplinary one and our program will feature latest developments across the entire spectrum. The goal of the GRS is to generate engaging dialogue between early career scientists and leaders in the field of cellular migration. The highlight of our program consist of two stimulating keynote talks by established field leaders and an interactive and lively “Ask the PI” panel session. This will provide the participants ample scope to network with the community for both scientific and career-related mentoring.

Related Meeting

This GRS will be held in conjunction with the "Directed Cell Migration" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
2:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm	Signal Integration in Cell Migration Discussion Leader: Tamas Nagy (University of California, San Francisco, USA)
3:45 pm - 4:00 pm	Andrew Kennard (University of Washington, USA) "Migratory 'Start' and 'Stop' Signals During Wound Healing In Vivo"
4:00 pm - 4:05 pm	Discussion
4:05 pm - 4:20 pm	Korbinian Kienle (Max Planck Institute of Immunobiology and Epigenetics, Germany) "Signal Adaptation Controls Neutrophil Swarming Dynamics at Local Sites of Inflammation and Infection"
4:20 pm - 4:25 pm	Discussion
4:25 pm - 4:30 pm	General Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Keynote Session: Cell Migration at the Crossroad of Form and Forces Discussion Leaders: Xiaoguang Li (Johns Hopkins University School of Medicine, USA) and Maria Lastra-Cagigas (University of New South Wales, Australia)
7:30 pm - 7:55 pm	Cecilia Moens (Fred Hutchinson Cancer Research Center, USA) "Directed Cell Migration in Zebrafish Nervous System Development"
7:55 pm - 8:00 pm	Discussion
8:00 pm - 8:15 pm	Audrey Williams (University of Chicago, USA) "Building a Planar Signaling System that Coordinates Migration Across an Epithelium"
8:15 pm - 8:20 pm	Discussion
8:20 pm - 8:35 pm	Anne Pipathsouk (University of California, San Francisco, USA) "A Template for Actin Organization at the Leading Edge"
8:35 pm - 8:40 pm	Discussion
8:40 pm - 8:55 pm	Abdiwahab Moalim (University of Toronto, Canada) "Calcium Sparks in Focal Adhesions Drive Cell Migration Along ECM Stiffness Gradients"
8:55 pm - 9:00 pm	Discussion
9:00 pm - 9:25 pm	Pere Roca-Cusachs (Institute for Bioengineering of Catalonia, Universitat de Barcelona, Spain) "Steering Migration and Mechanosensing Through Molecular Clutch Dynamics"
9:25 pm - 9:30 pm	Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Emerging Paradigms in Cellular Dynamics Discussion Leaders: Shailaja Seetharaman (Institut Pasteur, France) and Shannon Collins (University of Arizona, USA)
9:00 am - 9:15 am	Tadamoto Isogai (University of Texas Southwestern Medical Center, USA) "Arp2/3-Nucleated Dendritic Actin Networks Are Required Structures for Adhesion Formation and Cell Spreading in 3D"
9:15 am - 9:20 am	Discussion
9:20 am - 9:35 am	Ananya Mukherjee (Institute for Stem Cell Research and Regenerative Medicine (inStem), India) "Eyes in the Cell: Visualizing Active Kinases Using Genetically Encodable Fluorescent Biosensors"
9:35 am - 9:40 am	Discussion
9:40 am - 9:55 am	Sven Flemming (University of Potsdam, Germany) "How Actin Wave Dynamics Governs the Evolution of Cell Shape"
9:55 am - 10:00 am	Discussion
10:00 am - 10:15 am	Amit Das (Northeastern University, USA) "Different Modes of Fluidization in Human Bronchial Epithelial Cells: Unjamming Transition vs. Epithelial-Mesenchymal Transition"
10:15 am - 10:20 am	Discussion
10:20 am - 10:35 am	Zainalabdeen Alhashem (King's College London, United Kingdom) "Cell Cycle Regulates Leader Follower Identities During Collective Cell Migration"
10:35 am - 10:40 am	Discussion
10:40 am - 10:55 am	Sarah Hyun Ji Kim (University of Pennsylvania, USA) "CD4+ T Lymphocytes Migrate Upstream and Need VCAM1 to Display Directional Persistence After Flow"
10:55 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Mentorship Component: Ask the PI Discussion Leaders: Suvrajit Saha (University of California, San Francisco, USA) and Florian Gaertner (Institute of Science and Technology Austria, Austria)
1:30 pm - 2:30 pm	Panel Discussion Ask the PI Peter Friedl (Radboud University Nijmegen Medical Centre, The Netherlands) Sally Horne-Badovinac (University of Chicago, USA) Cecilia Moens (Fred Hutchinson Cancer Research Center, USA) Michael Sixt (Institute of Science and Technology Austria, Austria) Orion Weiner (UCSF School of Medicine, USA)
2:30 pm - 3:00 pm	Evaluation Period Fill in GRS Evaluation Forms
3:00 pm	Seminar Concludes

Contributors

Research reported in this publication was supported by the Eunice Kennedy Shriver National Institute Of Child Health & Human Development of the National Institutes of Health under Award Number R13HD097861. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

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Conference History Directed Cell Migration

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