Conference Description
The DNA Damage, Mutation and Cancer GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.
The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference topics are focused on synthesizing basic mechanisms of DNA damage repair to develop cancer biomarkers and therapeutics, as well as understand immune activation and aging. Of particular interest are aspects of chromosomal break repair and the DNA damage response, the DNA damage response as biomarkers and disease risk factors, structural insights into DNA repair pathways, DNA replication, and mechanisms of chromosomal rearrangements. Such topics will be connected to cancer biology, aging, and neurodegeneration. The conference will present new sessions on these topics and aims to consider new approaches and technologies. The conference will be all-inclusive and emphasize trainee participation beyond the associated Gordon Research Seminar (GRS) that will precede the GRC. There will be a Power Hour associated with the GRC where attendees from all levels of expertise are encouraged to participate in discussion of issues ranging from support and growth of women in science, support for all underrepresented persons in science, and aspects of work/life balance. The poster sessions will be an important part of the conference and an opportunity for trainees to present their work. The program will include times for short talks to be selected from submitted abstracts.
The topics, speakers, and discussion leaders for the conference sessions are displayed below. The conference chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by November 11, 2023. Please check back for updates.
Keynote Session: DNA Repair Mechanisms and Disease
Discussion Leaders
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Shan Zha (Columbia University, United States)
Speakers
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Wei Yang (National Institutes of Health, United States)
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Richard Wood (University of Texas MD Anderson Cancer Center, United States)
End Joining Mechanisms and Cancer Therapeutics
Discussion Leaders
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Yuan He (Northwestern University, United States)
Speakers
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Mauro Modesti (Cancer Research Center of Marseille, CNRS UMR7258, Aix Marseille University, France)
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Helen Robinson (Artios Pharma Ltd, United Kingdom)
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Dale Ramsden (University of North Carolina Lineberger Comprehensive Cancer Center, United States)
Structural Insights into the DNA Damage Response
Discussion Leaders
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Wei Yang (National Institutes of Health, United States)
Speakers
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Amanda Chaplin (The University of Leicester, United Kingdom)
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Sylvie Doublie (University of Vermont, United States)
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Melike Caglayan (UNIVERSITY OF FLORIDA, United States)
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Yuan He (Northwestern University, United States)
Mutations and Deregulation of the DNA Damage Response and Cancer
Discussion Leaders
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Maria Jasin (Memorial Sloan Kettering Cancer Center, United States)
Speakers
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Agata Smogorzewska (The Rockefeller University, United States)
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Dineo Khabele (Washington University School of Medicine, United States)
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Svasti Haricharan (Sanford Burnham Prebys, United States)
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Melinda Telli (Stanford University, United States)
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Elizabeth Christie (Peter MacCallum Cancer Centre, Australia)
DNA Replication and Cancer Therapy
Discussion Leaders
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Agata Smogorzewska (The Rockefeller University, United States)
Speakers
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Sharon Cantor (University of Massachusetts Medical School, United States)
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Maria Jasin (Memorial Sloan Kettering Cancer Center, United States)
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Yi Yin (UCLA, United States)
The DNA Damage Response and Chromosomal Rearrangements
Discussion Leaders
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Jessica Tyler (Weill Cornell Medicine, United States)
Speakers
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Christine Beck (The University of Connecticut Health Center and The Jackson Laboratory, United States)
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Tanya Paull (University of Texas at Austin, United States)
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Bo-Ruei Chen (University of Alabama at Birmingham, United States)
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Andre Nussenzweig (National Cancer Institute (NCI), National Institutes of Health (NIH), United States)
Mechanisms of Genome Maintenance
Discussion Leaders
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Richard Wood (University of Texas MD Anderson Cancer Center, United States)
Speakers
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Karen Vasquez (The University of Texas at Austin, United States)
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Jessica Tyler (Weill Cornell Medicine, United States)
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Richard Adeyemi (Fred Hutchinson Cancer Center, United States)
Genome Stability in the Brain
Discussion Leaders
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Tanya Paull (University of Texas at Austin, United States)
Speakers
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Peter McKinnon (St. Jude Children's Research Hospital, United States)
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E. Alice Lee (Boston Children's Hospital, United States)
DNA Damage and Immune Signaling
Discussion Leaders
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Andre Nussenzweig (National Cancer Institute (NCI), National Institutes of Health (NIH), United States)
Speakers
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Roger Greenberg (University of Pennsylvania, United States)
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Meredith Morgan (University of Michigan, United States)
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Samuel Bakhoum (Memorial Sloan Kettering Cancer Center, United States)
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Sun Hur (Harvard University & HHMI, United States)
The GRC Power Hourâ„¢
Organizers
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Karen Vasquez (The University of Texas at Austin, United States)