Sunday
|
2:00 pm - 9:00 pm |
Arrival and Check-in
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 7:40 pm |
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
|
7:40 pm - 9:30 pm |
Keynote Session: Nucleic Acid Therapeutics
Discussion Leader: Paul Burke (Burke Bioventures, USA)
|
7:40 pm - 8:10 pm |
Muthiah Manoharan (Alnylam Pharmaceuticals, USA)
"Drug Carriers for RNAi Therapeutics: From Principles to Patients"
|
8:10 pm - 8:20 pm |
Discussion
|
8:20 pm - 8:45 pm |
Katherine High (Spark Therapeutics, USA)
"Overview of the Development Program for Voretigene Neparvovec: Challenges and Solutions"
|
8:45 pm - 8:55 pm |
Discussion
|
8:55 pm - 9:20 pm |
Charles Gersbach (Duke University, USA)
"In Vivo Genome Engineering for Therapeutic and Research Applications"
|
9:20 pm - 9:30 pm |
Discussion
|
Monday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am - 12:30 pm |
Drug Delivery for Global Health
Discussion Leader: Dennis Lee (Bill and Melinda Gates Foundation, USA)
|
9:00 am - 9:30 am |
Darrell Irvine (Massachusetts Institute of Technology, USA)
"Vaccine Targeting at the Tissue and Cellular Level to Shape Immunity in Cancer and Infectious Disease"
|
9:30 am - 9:45 am |
Discussion
|
9:45 am - 10:15 am |
Ana Jaklenec (Massachusetts Institute of Technology, USA)
"Drug Delivery for Single Injection Vaccines"
|
10:15 am - 10:30 am |
Discussion
|
10:30 am - 11:00 am |
Coffee Break
|
11:00 am - 11:30 am |
Katherine Ferrara (Stanford University, USA)
"Bridging Focal and Immunotherapies"
|
11:30 am - 11:45 am |
Discussion
|
11:45 am - 12:15 pm |
Luis Brito (Moderna Therapeutics, USA)
"Delivery of Modified mRNA for Prevention of Infectious Diseases"
|
12:15 pm - 12:30 pm |
Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 9:30 pm |
Regeneration
Discussion Leader: Julie Champion (Georgia Institute of Technology, USA)
|
7:30 pm - 7:55 pm |
Tatiana Segura (Duke University, USA)
"Particle Hydrogels for Tissue Repair"
|
7:55 pm - 8:00 pm |
Discussion
|
8:00 pm - 8:25 pm |
David Thompson (Purdue University, USA)
"New Strategies to Address Unmet Medical Needs in Bladder Cancer and Lysosomal Storage Disorders"
|
8:25 pm - 8:30 pm |
Discussion
|
8:30 pm - 8:55 pm |
Kevin Healy (University of California, Berkeley, USA)
"Developing Engineered Systems to Explore Fundamental Biological Phenomena and New Applications in Translational Medicine"
|
8:55 pm - 9:00 pm |
Discussion
|
9:00 pm - 9:25 pm |
Milica Radisic (University of Toronto, Canada)
"Designer Biomaterials for Healing and Regeneration"
|
9:25 pm - 9:30 pm |
Discussion
|
Tuesday
|
7:30 am - 8:30 am |
Breakfast
|
8:30 am - 9:00 am |
Group Photo
|
9:00 am - 12:30 pm |
Immunotherapeutics
Discussion Leader: Kunwoo Lee (GenEdit Inc, USA)
|
9:00 am - 9:25 am |
Jimmy Weterings (Cristal Therapeutics, The Netherlands)
"CriPec® Nanomedicines: Building a Clinical Pipeline of Customizable Therapeutics"
|
9:25 am - 9:35 am |
Discussion
|
9:35 am - 10:00 am |
Matthias Stephan (Fred Hutchinson Cancer Research Center, USA)
"Synthetic mRNA Nanocarriers for the In Situ Programming of Disease-Specific Immune Cells"
|
10:00 am - 10:10 am |
Discussion
|
10:10 am - 10:35 am |
John Wilson (Vanderbilt University, USA)
"Engineering Nanotechnologies for Immuno-Oncology: Harnessing Cytosolic Immune Surveillance Pathways for Cancer Immunotherapy"
|
10:35 am - 10:45 am |
Discussion
|
10:45 am - 11:20 am |
Coffee Break
|
11:20 am - 11:45 am |
James Moon (University of Michigan, USA)
"Nanomaterials for Combination Cancer Immunotherapy"
|
11:45 am - 11:55 am |
Discussion
|
11:55 am - 12:20 pm |
Christopher Jewell (University of Maryland, College Park, USA)
"Modulating Immune Function Through Self-Assembly of Immune Signals"
|
12:20 pm - 12:30 pm |
Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 9:30 pm |
Drug Carriers for Oncology Targets and Oncology Micro-Environmental Factors
Discussion Leader: Paula Hammond (Massachusetts Institute of Technology, USA)
|
7:30 pm - 8:00 pm |
Jindrich Kopecek (University of Utah, USA)
"New Approaches for Treatment of Resistant Lymphomas"
|
8:00 pm - 8:10 pm |
Discussion
|
8:10 pm - 8:40 pm |
Francis Szoka (University of California, San Francisco, USA)
"Liposome Encapsulation of Sparingly Soluble Drugs-Nanoprecipitates Encased in a Lipid Bilayer"
|
8:40 pm - 8:50 pm |
Discussion
|
8:50 pm - 9:20 pm |
Mark Grinstaff (Boston University, USA)
"Functional Nanoparticles for Oncology"
|
9:20 pm - 9:30 pm |
Discussion
|
Wednesday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am - 12:30 pm |
Therapeutic Antibody-Drug Conjugates, Peptides and Proteins
Discussion Leader: Maria Vicent (Centro de Investigacion Principe Felipe, Spain)
|
9:00 am - 9:30 am |
Ravi Chari (ImmunoGen, USA)
"Approaches to Improve the Clinical Success of Antibody-Drug Conjugates"
|
9:30 am - 9:45 am |
Discussion
|
9:45 am - 10:15 am |
Heather Maynard (University of California, Los Angeles, USA)
"Sweet Stabilizers: Synthesis of Glycopolymers and Mimetics for Therapeutic Protein Delivery"
|
10:15 am - 10:30 am |
Discussion
|
10:30 am - 11:00 am |
Coffee Break
|
11:00 am - 11:30 am |
David Rabuka (Catalent Pharma Solutions, USA)
"Developing ADCs Using a Chemoenzymatic Approach"
|
11:30 am - 11:45 am |
Discussion
|
11:45 am - 12:15 pm |
Peter Senter (Seattle Genetics, USA)
"Antibody-Based Therapeutics for Cancer Therapy: An Early Stage Research to a Clinically Approved Drug"
|
12:15 pm - 12:30 pm |
Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:00 pm - 7:30 pm |
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
|
7:30 pm - 9:30 pm |
Selected Poster Presentations
Discussion Leaders: Suzie Pun (University of Washington, USA) and Samir Mitragotri (Harvard University, USA)
|
7:30 pm - 7:40 pm |
Kathryn Whitehead (Carnegie Mellon University, USA)
"Lipid Nanoparticle Formulations for Synergistic Co-Delivery of siRNA and mRNA"
|
7:40 pm - 7:45 pm |
Discussion
|
7:45 pm - 7:55 pm |
Natalie Artzi (Brigham and Women's Hospital / Harvard Medical School / Massachusetts Institute of Technology, USA)
"Cancer-Specific and Biologically-Informed (Nano)materials"
|
7:55 pm - 8:00 pm |
Discussion
|
8:00 pm - 8:10 pm |
Jiahe Li (Massachusetts Institute of Technology, USA)
"Structurally Modulated Codelivery of siRNA and Argonaute 2 for Enhanced RNA Interference"
|
8:10 pm - 8:15 pm |
Discussion
|
8:15 pm - 8:25 pm |
Harvinder Gill (Texas Tech University, USA)
"Pollen Grains for Oral Vaccination"
|
8:25 pm - 8:30 pm |
Discussion
|
8:30 pm - 8:40 pm |
James Dahlman (Georgia Institute of Technology / Emory University School of Medicine, USA)
"Using DNA Barcodes to Measure How Thousands of Nanoparticles Deliver Drugs In Vivo"
|
8:40 pm - 8:45 pm |
Discussion
|
8:45 pm - 8:55 pm |
Nitasha Bennett (Massachusetts Institute of Technology, USA)
"Injectable Silk Micro-Implants for Localized Immune Modulation of the Breast Tumor Microenvironment"
|
8:55 pm - 9:00 pm |
Discussion
|
9:00 pm - 9:10 pm |
Juliane Nguyen (University at Buffalo, USA)
"miR-101 Enriched MSC Exosomes Mediate Cardioprotection Through Anti-Fibrotic and Immunomodulatory Effects"
|
9:10 pm - 9:15 pm |
Discussion
|
9:15 pm - 9:25 pm |
Michael Mitchell (University of Pennsylvania, USA)
"Nanoparticle-Mediated RNAi in the Hematopoietic Stem Cell Niche"
|
9:25 pm - 9:30 pm |
Discussion
|
Thursday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am - 12:30 pm |
New Carriers and Systems
Discussion Leader: Anna Schwendeman (University of Michigan, USA)
|
9:00 am - 9:30 am |
Kazunori Kataoka (Innovation Center of NanoMedicine (iCONM), Kawasaki Institute of Industrial Promotion, Japan)
"Unit PIC Carrier for Cligonucleotides and/or Glucose-Conjugated Nanocarrier for Crossing BBB"
|
9:30 am - 9:45 am |
Discussion
|
9:45 am - 10:15 am |
Moritz Kircher (Memorial Sloan Kettering Cancer Center, USA)
"Modular Surface-Enhanced Raman Nanoparticles for High Precision Cancer Imaging"
|
10:15 am - 10:30 am |
Discussion
|
10:30 am - 11:00 am |
Coffee Break
|
11:00 am - 11:30 am |
David Putnam (Cornell University, USA)
"Design and Implementation of Kinetic Models for the Intracellular Delivery of Bacteriophage"
|
11:30 am - 11:45 am |
Discussion
|
11:45 am - 12:15 pm |
Jacob Brenner (University of Pennsylvania, USA)
"Nanomedicine for Acute Critical Illness"
|
12:15 pm - 12:30 pm |
Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 9:30 pm |
Local Delivery
Discussion Leader: Millicent Sullivan (University of Delaware, USA)
|
7:30 pm - 8:00 pm |
Tejal Desai (University of California, San Francisco, USA)
"Nanostructured Materials for Local Biologic Delivery and Immunomodulation"
|
8:00 pm - 8:10 pm |
Discussion
|
8:10 pm - 8:40 pm |
Jesse Jokerst (University of California, San Diego, USA)
"Acoustic and Photoacoustic Imaging to Guide and Monitor Drug Delivery"
|
8:40 pm - 8:50 pm |
Discussion
|
8:50 pm - 9:20 pm |
Patrick Stayton (University of Washington, USA)
"Drugamer Prodrugs for Infectious Disease and Immune Therapy"
|
9:20 pm - 9:30 pm |
Discussion
|
Friday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am |
Departure
|