Conference Description
The study of enzymes, co-enzymes and metabolic pathways has defined our understanding of cellular biochemistry, enabled discovery of new therapeutic agents and even allowed the generation of new materials. In the early days, the principles of enzymology were established using relatively simple systems. As our biomolecular toolset has continued to improve, these basic concepts have enabled us to study more complex systems, providing a much deeper understanding of how enzymes function in multiple contexts. In recognition of these advances, the 2021 Gordon Research Conference on Enzymes, Coenzymes and Metabolic Pathways will embrace the fundamentals, including enzyme mechanism, inhibition and metabolism, while exploring new horizons, such as enzymes that use double-stranded RNA as substrates, enzyme structural advances and kinetics in cells or on the single-molecule level.
The topics, speakers, and discussion leaders for the conference sessions are displayed below. The conference chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by March 18, 2021. Please check back for updates.
Enzymology in the Innate Immune System
Discussion Leaders
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Heather Hundley (Indiana University, USA)
Speakers
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James Cole (University of Connecticut, USA)
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Peter Beal (University of California, Davis, USA)
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Yorgo Modis (University of Cambridge, United Kingdom)
Enzyme Mechanisms
Discussion Leaders
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Katherine Hicks (SUNY Cortland, USA)
Speakers
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Squire Booker (Pennsylvania State University, USA)
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Emily Parker (Victoria University of Wellington, New Zealand)
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Manal Swairjo (San Diego State University, USA)
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Timothy Wencewicz (Washington University in St. Louis, USA)
Enzymes Involved in Post-Translational Modifications
Discussion Leaders
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Walter Fast (University of Texas at Austin, USA)
Speakers
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Sonja Lorenz (University of Würzburg, Germany)
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Minkui Luo (Memorial Sloan Kettering Cancer Center, USA)
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Paul Thompson (University of Massachusetts Medical School, USA)
Enzyme Kinetics in Complex Systems
Discussion Leaders
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Erin Artin (KSQ Therapeutics, USA)
Speakers
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Swati Nagar (Temple University, USA)
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Matthew Robers (Promega, USA)
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Peter Tonge (Stony Brook University, USA)
Conformational Effects on Catalysis and Inhibition
Discussion Leaders
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Patrick Frantom (The University of Alabama, USA)
Speakers
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James Fraser (University of California, San Francisco, USA)
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Randy Kipp (Relay Therapeutics, USA)
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John Richard (University at Buffalo, SUNY, USA)
Inhibitor Design
Discussion Leaders
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Victoria Korboukh (AstraZeneca, USA)
Speakers
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Argyrides Argyrou (AstraZeneca, United Kingdom)
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Elham Behshad (Incyte, USA)
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Andrew Bennet (Simon Fraser University, Canada)
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Caren Freel Meyers (Johns Hopkins University School of Medicine, USA)
Enzyme Evolution and Engineering
Discussion Leaders
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Nicholas Silvaggi (University of Wisconsin-Milwaukee, USA)
Speakers
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Michael Toney (University of California, Davis, USA)
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Dan Tawfik (Weizmann Institute of Science, Israel)
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Donald Hilvert (ETH Zurich, Switzerland)
Methodological Advances for Studying Enzymes
Discussion Leaders
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Audrey Lamb (University of Kansas, USA)
Speakers
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David Dulin (Friedrich-Alexander University Erlangen-Nürnberg, Germany)
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Gabriel Lander (Scripps Research, USA)
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Denis Rousseau (Albert Einstein College of Medicine, USA)
Perspectives on Modulation of Enzyme Activity
Discussion Leaders
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Catherine Drennan (Massachusetts Institute of Technology, USA)
Speakers
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Paul Fitzpatrick (University of Texas Health Science Center at San Antonio, USA)
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Carol Fierke (Texas A&M University, USA)
The GRC Power Hour™
Organizer:
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Lynn Abell (Agios Pharmaceuticals, USA)
