| SUNDAY | 
| 2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) | 
| 6:00 pm | Dinner | 
| 7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff | 
| 7:40 pm - 9:30 pm | Differentiation and Disease in Diverse Epithelia | 
|  | Discussion Leader: Pierre Coulomb (Hopkins) | 
| 7:40 pm - 8:10 pm | Andy McMahon (Harvard) "Generating cell diversity within the mammalian neural epithelium through Shh signaling"
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| 8:10 pm - 8:20 pm | Discussion | 
| 8:20 pm - 8:50 pm | Connie Cepko (Harvard) "Cell Fate Determination in the Vertebrate Retina"
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| 8:50 pm - 9:00 pm | Discussion | 
| 9:00 pm - 9:20 pm | Paul Khavari (Stanford) "Mechanisms Of Genomic Reprogramming During Epidermal Differentiation"
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| 9:20 pm - 9:30 pm | Discussion | 
| MONDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | Epidermal Homeostasis and Barrier Function | 
|  | Discussion Leader: Sabine Warner (Zürich) | 
| 9:00 am - 9:20 am | Jenny Jiang (University of California, San Francisco) "The Role Of Lipids In The Formation Of The Cutaneous Permeability Barrier And Coordinately Regulating Keratinocyte Differentiation"
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| 9:20 am - 9:30 am | Discussion | 
| 9:30 am - 9:50 am | Masa Amagai (Keio University, Tokyo, Japan) "Mechanisms of epidermal barrier and its dysfunction in atopic diseases"
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| 9:50 am - 10:00 am | Discussion | 
| 10:00 am | Group Photo / Coffee Break | 
| 10:30 am - 10:50 am | Ellen Lumpkin (Columbia) "The Role Of Epidermal Merkel Cells In Touch Sensation"
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| 10:50 am - 11:00 am | Discussion | 
| 11:00 am - 11:20 am | Zhou Feng Chen (Washington University) "GRPR: transmitting itch sensation to the spinal cord"
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| 11:20 am - 11:30 am | Discussion | 
| 11:30 am - 11:50 am | Anj Dlugosz (U. Michigan) "Cell of Origin and Signaling Activity Influence Hedgehog-Driven Skin Tumorigenesis"
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| 11:50 am - 12:00 pm | Discussion | 
| 12:00 pm - 12:15 pm | Scott Atwood (Stanford) "Canonical polarity protein aPKC iota/lambda regulates Shh signaling during basal cell carcinoma growth"
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| 12:15 pm - 12:20 pm | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 6:00 pm | Poster Session | 
| 6:00 pm | Dinner | 
| 7:30 pm - 9:30 pm | Therapeutic Applications of Skin Cells | 
|  | Discussion Leader: Angela Christiano (Columbia University, NY) | 
| 7:30 pm - 7:50 pm | Danwei Huangfu (Memorial Sloan Kettering) "Reprogramming Cell Identity for Regenerative Medicine"
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| 7:50 pm - 8:00 pm | Discussion | 
| 8:00 pm - 8:20 pm | Tony Oro (Stanford) "Determinants of Epithelial Morphogenesis during Tissue Regeneration"
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| 8:20 pm - 8:30 pm | Discussion | 
| 8:30 pm - 8:50 pm | Dennis Roop (Denver) "Testing the Therapeutic Potential of iPS Cells for Inherited Skin Diseases"
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| 8:50 pm - 9:00 pm | Discussion | 
| TUESDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | Epithelial Morphogenesis | 
|  | Discussion Leader: Radhika Atit (Case Western) | 
| 9:00 am - 9:20 am | Ping Chen (Emory, USA) "Planar Cell Polarization In The Mammalian Inner Ear Sensory Epithelia"
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| 9:20 am - 9:30 am | Discussion | 
| 9:30 am - 9:50 am | Arjun Raj (Penn) "Variability In Gene Expression Underlies Incompletely Penetrant Phenotypes"
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| 9:50 am - 10:00 am | Discussion | 
| 10:00 am | Coffee Break | 
| 10:30 am - 10:50 am | Angela Christiano (Colombia) "Danger Signals in the Hair Follicle"
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| 10:50 am - 11:00 am | Discussion | 
| 11:00 am - 11:20 am | Bruce Morgan (Harvard) "Size Matters: Genetic Networks In The Dermal Papilla That Regulate Organ Size"
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| 11:20 am - 11:30 am | Discussion | 
| 11:30 am - 11:50 am | Cheng-Ming Chuong (USC) "Macro-Environmental Regulation Of Skin Appendage Stem Cell Activity"
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| 11:50 am - 12:00 pm | Discussion | 
| 12:00 pm - 12:20 pm | Elsa Flores (MD Anderson) "Unraveling The Diverse Functions Of The TA And DN Isoforms Of P63 In Epidermal Morphogenesis And Stem Cell Maintenance"
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| 12:20 pm - 12:30 pm | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 6:00 pm | Poster Session | 
| 6:00 pm | Dinner | 
| 7:30 pm - 9:30 pm | Skin Stem Cells | 
|  | Discussion Leader: Doina Tumbar (Cornell) | 
| 7:30 pm - 7:50 pm | Phil Jones "Molecular regulation of stochastic cell fate in normal and preneoplastic epidermal progenitor cells"
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| 7:50 pm - 8:00 pm | Discussion | 
| 8:00 pm - 8:20 pm | Elaine Fuchs (Rockefeller) "Integrating Cytoskeletal Dynamics With Stem Cells in Morphogenesis and Wound Repair"
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| 8:20 pm - 8:30 pm | Discussion | 
| 8:30 pm - 8:50 pm | Fiona Watt (MRC) "Reciprocal Signaling Between Adult Epidermis And Dermis"
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| 8:50 pm - 9:00 pm | Discussion | 
| 9:00 pm - 9:20 pm | George Cotsarelis (Penn) "Factors influencing hair follicle neogenesis following wounding"
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| 9:20 pm - 9:30 pm | Discussion | 
| WEDNESDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | The Role of Immune System in Epithelial Biology and Disease | 
|  | Discussion Leader: Stuart Yuspa (NIH, USA) | 
| 9:00 am - 9:30 am | Keynote: Joan Brugge (Harvard) "Modeling Morphogenesis and Oncogenesis of Epithelial Cells in Culture"
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| 9:30 am - 9:40 am | Discussion | 
| 9:40 am - 10:10 am | Michael Girardi (Yale) "Local Immune Influences on Cutaneous Carcinogenesis"
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| 10:10 am - 10:20 am | Discussion | 
| 10:20 am | Coffee Break | 
| 10:50 am - 11:10 am | Freddy Radtke (EPFL ISREC, Switzerland) "TSLP-Mediated Inflammation and Skin Cancer"
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| 11:10 am - 11:20 am | Discussion | 
| 11:20 am - 11:40 am | Birgit Lane (Institute of Medical Biology, Singapore) "Multiple self-healing squamous epithelioma is caused by a disease-specific spectrum of mutations in TGFBR1"
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| 11:40 am - 11:50 am | Discussion | 
| 11:50 am - 12:10 pm | Christophe Cataisson (NCI) "IL-1a Is A Major Effector Of The Ras Oncogenic Program"
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| 12:10 pm - 12:20 pm | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 6:00 pm | Poster Session | 
| 6:00 pm | Dinner | 
| 7:00 pm - 7:30 pm | Business Meeting | 
|  | Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair | 
| 7:30 pm - 9:30 pm | Issues Arising Session | 
|  | Discussion Leader: Sarah Millar (U Penn) | 
| 7:30 pm - 7:40 pm | Markus Kretz (Stanford) "Epidermal homeostasis is regulated by the functionally antagonistic long non-coding RNAs, ANCR and TINCR"
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| 7:40 pm - 7:45 pm | Discussion | 
| 7:45 pm - 7:55 pm | Vladimir Botchkarev (University Of Bradford / Boston University) "The genome organizer protein Satb1 controls the establishment of tissue-specific chromatin organization during epidermal development"
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| 7:55 pm - 8:00 pm | Discussion | 
| 8:00 pm - 8:10 pm | Carien Niessen (University of Cologne) "Polarity signaling controls epidermal morphogenesis, homeostasis and stem cell behavior"
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| 8:10 pm - 8:15 pm | Discussion | 
| 8:15 pm - 8:25 pm | Marja Mikkola (University of Helsinki) "Molecular mechanisms regulating dermal condensate formation"
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| 8:25 pm - 8:30 pm | Discussion | 
| 8:30 pm - 8:40 pm | Amanda Nelson (Johns Hopkins) "Prostaglandin D2 levels inversely correlate with hair follicle regeneration in mice"
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| 8:40 pm - 8:45 pm | Discussion | 
| 8:45 pm - 8:55 pm | Elena Ezhkova (Mount Sinai, NY) "EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair"
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| 8:55 pm - 9:00 pm | Discussion | 
| 9:00 pm - 9:10 pm | Valerie Horsley (Yale) "Extrinsic Regulation of Follicular Stem Cells by Adipocytes"
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| 9:10 pm - 9:15 pm | Discussion | 
| 9:15 pm - 9:25 pm | Tudorita Tumbar (Cornell University) "Runx1 is a master regulator of adult hair follicle stem cells activation, emergence, and maintenance, and promotes skin tumorigenesis"
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| 9:25 pm - 9:30 pm | Discussion | 
| THURSDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | Polarity, Adhesion, and Cytoskeleton | 
|  | Discussion Leader: Tung-Tien (Henry) Sun (NYU, NY) | 
| 9:00 am - 9:20 am | Greg Longmore (Washington University) "Rho Gtpases In Remodeling Epithelia, In Vivo"
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| 9:20 am - 9:30 am | Discussion | 
| 9:30 am - 9:50 am | Pierre Coulombe (Johns Hopkins University) "Non-Canonical Functions Of Keratin In Skin Epithelia"
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| 9:50 am - 10:00 am | Discussion | 
| 10:00 am | Coffee Break | 
| 10:30 am - 10:50 am | Kathy Green (Northwestern, USA) "Desmosomes: Signaling Scaffolds in Epidermal Morphogenesis"
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| 10:50 am - 11:00 am | Discussion | 
| 11:00 am - 11:20 am | Terry Lechler (Duke) "Generation and Function of Cortical Microtubules in the Epidermis"
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| 11:20 am - 11:30 am | Discussion | 
| 11:30 am - 11:50 am | Benjamin Yu (UCSD) "Discovery Of Small RNAs In The Human Hair Shaft: Implications For Molecular And Genetic Basis For Human Variation"
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| 11:50 am - 12:00 pm | Discussion | 
| 12:00 pm - 12:20 pm | Sarah Millar (U Penn USA) "HDAC1 and HDAC2: keeping the embryonic epidermis young"
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| 12:20 pm - 12:30 pm | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 6:00 pm | Poster Session | 
| 6:00 pm | Dinner | 
| 7:30 pm - 9:30 pm | Novel Regulatory Mechanisms | 
|  | Discussion Leader: Bogi Andersen (Irvine, CA) | 
| 7:30 pm - 7:50 pm | Paolo Dotto (Lausanne; Harvard) "Notch And Calcineurin Signaling In Integrated Control Of Skin Homeostasis And Carcinogenesis"
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| 7:50 pm - 8:00 pm | Discussion | 
| 8:00 pm - 8:20 pm | Howard Chang (Stanford USA) "Genome regulation by long noncoding RNAs"
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| 8:20 pm - 8:30 pm | Discussion | 
| 8:30 pm - 8:50 pm | Harinder Singh (Genentech) "Developmental Control Of Gene Activity Via Compartmentalization At The Nuclear Lamina"
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| 8:50 pm - 9:00 pm | Discussion | 
| 9:00 pm - 9:20 pm | Rui Yi (Boulder) "microRNA-mediated regulation of maintenance and differentiation of skin stem cells"
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| 9:20 pm - 9:30 pm | Discussion | 
| FRIDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am | Departure |